Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_2232Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanchorioamniotic membranesLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2232Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humanchorioamniotic membranesLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2233Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2233Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2234Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 8 (TLR8)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainQ9NR97.fastaQ9NR971041NANA293306752017Pubchem_assay
PRRID_2234Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 8 (TLR8)Toll-like receptor (TLR)Humanluminal epithelial cells of the prostrateLeucine-rich Repeat (LRR) DomainQ9NR97.fastaQ9NR971041NANA293306752017Pubchem_assay
PRRID_2237Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA292639322017Pubchem_assay
PRRID_2237Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA292639322017Pubchem_assay
PRRID_2238Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanPlateletsleucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD)O00206.fastaO00206839release soluble factors to modulate the immune responseNA292205942017Pubchem_assay
PRRID_2238Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanPlateletsleucine-rich-repeat (LRR) , nucleotide-binding domain (NBD), caspase activation and recruitment domain (CARD)O00206.fastaO00206839release soluble factors to modulate the immune responseNA292205942017Pubchem_assay
PRRID_2239Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses Mastitis, an infection of the mammary glandToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanmammary tissueLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291138062017Pubchem_assay
PRRID_2239Lipopolysaccharide (LPS)

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Gram negative Bacteria (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalCauses Mastitis, an infection of the mammary glandToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanmammary tissueLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291138062017Pubchem_assay
PRRID_2240Lipopolysaccharide (LPS)

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E. coli K12(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalanti- inflammatory activityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanU937 cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291137972017Pubchem_assay
PRRID_2240Lipopolysaccharide (LPS)

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E. coli K12(Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalanti- inflammatory activityToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanU937 cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA291137972017Pubchem_assay
PRRID_2241Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalUrinary Tract infectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbladder and uroepithelial cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290663052017Pubchem_assay
PRRID_2241Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalUrinary Tract infectionToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbladder and uroepithelial cellsLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290663052017Pubchem_assay
PRRID_2242Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNANAO00206.fastaO00206839NANA290662552017Pubchem_assay
PRRID_2242Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNANAO00206.fastaO00206839NANA290662552017Pubchem_assay
PRRID_2253Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Humansurface of epithelial cells and some hematopoietic cellsNAA0A087X2A4.fastaA0A087X2A4484phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2253Lipopolysaccharide (LPS)

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Pseudomonas aeruginosa (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)Naturalstimulation of THP-1 macrophagesMUC1 mucinPattern recognition receptor (PRR)Humansurface of epithelial cells and some hematopoietic cellsNAA0A087X2A4.fastaA0A087X2A4484phagocytic activity and cytokine productionELISA288227662017Pubchem_assay
PRRID_2257Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2257Lipopolysaccharide (LPS)

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BacteriaCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanbrain(hippocampus, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2286Lipoprotein

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BacteriaNANANANaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanNANAO60603.fastaO60603784NANA290662552017Pubchem_assay
PRRID_2286Lipoprotein

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BacteriaNANANANaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanNANAO60603.fastaO60603784NANA290662552017Pubchem_assay
PRRID_2287Lipoprotein

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BacteriaNANANANaturalStimulate NFκB, induce apoptosis in THP- monocytice cellsToll-like receptor 6 (TLR6)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainQ9Y2C9.fastaQ9Y2C9796NANA290283692017Pubchem_assay
PRRID_2287Lipoprotein

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BacteriaNANANANaturalStimulate NFκB, induce apoptosis in THP- monocytice cellsToll-like receptor 6 (TLR6)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainQ9Y2C9.fastaQ9Y2C9796NANA290283692017Pubchem_assay
PRRID_2288Lipoprotein

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S. gordonii (Bacteria)NANAPattern-associated molecular patterns (PAMPs)Naturalapical periodontitisToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanPDL cellsLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784induces IL-8 production through activation of TLR2 in human PDL cells.ELISA289639312017Pubchem_assay
PRRID_2288Lipoprotein

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S. gordonii (Bacteria)NANAPattern-associated molecular patterns (PAMPs)Naturalapical periodontitisToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanPDL cellsLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784induces IL-8 production through activation of TLR2 in human PDL cells.ELISA289639312017Pubchem_assay
PRRID_2291Lipoprotein

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Human(hippocampus, entorhinal cortex, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2291Lipoprotein

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Human(hippocampus, entorhinal cortex, superior frontal gyrus, post-central gyrus)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784mRNA ‚Üë in aging and ADNA288015212017Pubchem_assay
PRRID_2294Lipoprotein

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanBrain(neurons)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784protein ‚Üë in PDNA288015212017Pubchem_assay
PRRID_2294Lipoprotein

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BacteriaNANAPattern-associated molecular patterns (PAMPs)NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanBrain(neurons)Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784protein ‚Üë in PDNA288015212017Pubchem_assay
PRRID_2297Lipoteichoic Acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalNFκB activation and cytokine productionToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanHuman embryonic kidney 293 (HERK 293 ) cellsLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA290283692017Pubchem_assay
PRRID_2297Lipoteichoic Acid (LTA)

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BacteriaC(C1C(C(C(C(O1)OCC(CO)O)OC2C(C(C(C(O2)COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(COP(=O)(O)OCC(CO)O)O)O)O)O)O)O)O)O)ONAAmphiphileNaturalNFκB activation and cytokine productionToll-like receptor 2 (TLR2)Toll-like receptor (TLR)HumanHuman embryonic kidney 293 (HERK 293 ) cellsLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA290283692017Pubchem_assay
PRRID_2309Long ds RNA

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EMCV, poliovirus and coxasackie virus; Rotavirus, dengue virus, WNV, murine hepatitis virus(virus)NANAPattern-associated molecular patterns (PAMPs)Naturalfilament formation mediated receptor tetramerizationMDA5Rig-like receptor (RLR)HumanCytoplasm, all mammalian cell typesNAQ53TB6.fastaQ53TB6435MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jBNA283749032017Pubchem_assay
PRRID_2309Long ds RNA

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EMCV, poliovirus and coxasackie virus; Rotavirus, dengue virus, WNV, murine hepatitis virus(virus)NANAPattern-associated molecular patterns (PAMPs)Naturalfilament formation mediated receptor tetramerizationMDA5Rig-like receptor (RLR)HumanCytoplasm, all mammalian cell typesNAQ53TB6.fastaQ53TB6435MAVS-TRAF3-TBK1/ IKKe-IRF3. MAVS-FADD/ TRAF6-IKKs-NF-jBNA283749032017Pubchem_assay
PRRID_2311Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine)

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SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus) C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)ONAPattern-associated molecular patterns (PAMPs)NaturalZ-loop proteolytic cleavage, and receptor dimer conformational changeToll-like receptor 7 (TLR7)Toll-like receptor (TLR)HumanEndosomes. pDCs and B cellsLeucine-rich Repeat (LRR) DomainQ9NYK1.fastaQ9NYK11049MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jBNA283749032017Pubchem_assay
PRRID_2311Loxoribine (7-allyl-7,8-dihydro-8-oxo-guanosine)

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SeV, flu virus, coxsackie virus, vaccinia virus, MV, RSV, retrovirus (virus) C=CCN1C2=C(NC(=NC2=O)N)N(C1=O)C3C(C(C(O3)CO)O)ONAPattern-associated molecular patterns (PAMPs)NaturalZ-loop proteolytic cleavage, and receptor dimer conformational changeToll-like receptor 7 (TLR7)Toll-like receptor (TLR)HumanEndosomes. pDCs and B cellsLeucine-rich Repeat (LRR) DomainQ9NYK1.fastaQ9NYK11049MyD88-IRAK4/ IRAK1-IRF7. MyD88-IRAF6- IKKs-NF-jBNA283749032017Pubchem_assay
PRRID_2321M-Tri-DAP

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)NNAPeptidoglycanSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2321M-Tri-DAP

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)NC(CCCC(C(=O)O)N)C(=O)O)C(=O)O)NNAPeptidoglycanSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2324Mannan

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Fungi(Yeast)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalActivate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophagesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290283692017Pubchem_assay
PRRID_2324Mannan

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Fungi(Yeast)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalActivate macrophages and produce inflammatory responses, Induce NF-κB activation, induce PGE2, IL-1β, and TNF-α production, by macrophagesToll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanNALeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA290283692017Pubchem_assay
PRRID_2329Mannose and fucose

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L. monocytogenes (Bacteria)C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalActivation of CLEC5ACLEC5AC type Lectin (CTL/CLR)Humanmonocytes, macrophages and neutrophils.NAQ14DL9.fastaQ14DL9165secretion of proinflammatory cytokines such as TNF, IL-6, CXCL-8, and IP-10.Binding assay288241662017Pubchem_assay
PRRID_2329Mannose and fucose

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L. monocytogenes (Bacteria)C(C1C(C(C(C(O1)O)O)O)O)O and CC(C(C(C(C=O)O)O)O)ONAPattern-associated molecular patterns (PAMPs)NaturalActivation of CLEC5ACLEC5AC type Lectin (CTL/CLR)Humanmonocytes, macrophages and neutrophils.NAQ14DL9.fastaQ14DL9165secretion of proinflammatory cytokines such as TNF, IL-6, CXCL-8, and IP-10.Binding assay288241662017Pubchem_assay
PRRID_2331Maturing conidia

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Aspergillus fumigatus(fungi)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRHumanNANAQ9BXN2.fastaQ9BXN2247Protective role in infection modelNA281676512017Pubchem_assay
PRRID_2331Maturing conidia

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Aspergillus fumigatus(fungi)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantDectin-1 (Clec7a)Syk-coupled CLRHumanNANAQ9BXN2.fastaQ9BXN2247Protective role in infection modelNA281676512017Pubchem_assay
PRRID_2335MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Humanhippocampus (neurons)NAQ9C000.fastaQ9C0001473protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2335MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)Humanhippocampus (neurons)NAQ9C000.fastaQ9C0001473protein ‚Üë in AD, role in neuronal pyroptosis and cognitive impairmentNA288015212017Pubchem_assay
PRRID_2338MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)HumanBrainNAQ9C000.fastaQ9C0001473protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2338MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNA Nod-like receptor protein 1 (NLRP1)NOD-like receptor (NLR)HumanBrainNAQ9C000.fastaQ9C0001473protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2340MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2340MDP (muramyldipeptide)

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Gram-negative and Gram-positive bacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNAPeptideNaturalNANod-like receptor P3 (NLRP3)NOD-like receptor (NLR)HumanBrainNAQ96P20.fastaQ96P201036protein ‚Üë in ischemia/reperfusion, role in neuronal cell death and behavioral deficitsNA288015212017Pubchem_assay
PRRID_2343Microbial DNA

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E. coli(Bacteria)MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK396Pattern-associated molecular patterns (PAMPs)NaturalBacterial infectionDC-SIGNC type Lectin (CTL/CLR)HumanmonocytesNANANANANANA289769992017NA
PRRID_2343Microbial DNA

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E. coli(Bacteria)MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK396Pattern-associated molecular patterns (PAMPs)NaturalBacterial infectionDC-SIGNC type Lectin (CTL/CLR)HumanmonocytesNANANANANANA289769992017NA
PRRID_2344Microfilarial protein (MfP)

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W. bancrofti (others)NANAPattern-associated molecular patterns (PAMPs)Naturalbinds to macrophage-TLR4 and triggers NF-κB activation that up-regulates secretion of proinflammatory cytokines.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMacrophagesLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NF-κB activation that up-regulates secretion of proinflammatory cytokines.co-immunoprecipitation, FITC-probing and Surface Plasmon Resonance analysis.284538502017Pubchem_assay
PRRID_2344Microfilarial protein (MfP)

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W. bancrofti (others)NANAPattern-associated molecular patterns (PAMPs)Naturalbinds to macrophage-TLR4 and triggers NF-κB activation that up-regulates secretion of proinflammatory cytokines.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)HumanMacrophagesLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NF-κB activation that up-regulates secretion of proinflammatory cytokines.co-immunoprecipitation, FITC-probing and Surface Plasmon Resonance analysis.284538502017Pubchem_assay
PRRID_2345mono- and di-acylated derivatives

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NANANAAgonistSyntheticActivation of CLRs.MincleC type Lectin (CTL/CLR)HumanPlasma membranecarbohydrate recognition domain (CRD)Q9ULY5.fastaQ9ULY5219inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways.Flow cytometry287764162017Pubchem_assay
PRRID_2345mono- and di-acylated derivatives

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NANANAAgonistSyntheticActivation of CLRs.MincleC type Lectin (CTL/CLR)HumanPlasma membranecarbohydrate recognition domain (CRD)Q9ULY5.fastaQ9ULY5219inhibit TLR immune response pathways while independently triggering inflammatory cytokines or can act in synergy with TLR pathways.Flow cytometry287764162017Pubchem_assay
PRRID_2346monomeric lipopolysaccharide

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NANANANANaturalNAcluster of differentiation 14 (CD14)Pattern recognition receptor (PRR)HumanNANAP08571.fastaP08571375NANA290662552017Pubchem_assay
PRRID_2346monomeric lipopolysaccharide

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NANANANANaturalNAcluster of differentiation 14 (CD14)Pattern recognition receptor (PRR)HumanNANAP08571.fastaP08571375NANA290662552017Pubchem_assay
PRRID_2347mt-DNA

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All vertebrates(others)NANANucleic AcidNaturalCellular injury and necrosisToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanGranulocytes and monocytesLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NRN6154release of interferon type 1 and TNF-a through the activation of IL-1R-associated kinase 1, 2, and 4 and the phosphorylation of p38 MAPKNA280491422017Pubchem_assay
PRRID_2347mt-DNA

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All vertebrates(others)NANANucleic AcidNaturalCellular injury and necrosisToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanGranulocytes and monocytesLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NRN6154release of interferon type 1 and TNF-a through the activation of IL-1R-associated kinase 1, 2, and 4 and the phosphorylation of p38 MAPKNA280491422017Pubchem_assay
PRRID_2350muramyl dipeptide (MDP)

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BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2350muramyl dipeptide (MDP)

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BacteriaCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)CNANANaturalNANucleotide Binding Oligomerization Domain Containing 2 (Nod2)NOD-like receptor (NLR)HumanNANucleotide-binding oligomerization domain 2,Q9HC29.fastaQ9HC291040NANA290662552017Pubchem_assay
PRRID_2356Mycoplasma

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Pathogens (others)NANAFatty acid NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA292639322017Pubchem_assay
PRRID_2356Mycoplasma

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Pathogens (others)NANAFatty acid NaturalNAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humancell surfaceLeucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA292639322017Pubchem_assay
PRRID_2361N-acetylmuramic acid

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2361N-acetylmuramic acid

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NC(=O)CNAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C2 (NLRC2)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2362N-acyl glutamyl DAP

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NANANAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2362N-acyl glutamyl DAP

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NANANAAgonistSyntheticAgonist recognition triggers receptor oligomerization and recruitment of signaling molecules that drive NF-κB-mediated expression of inflammatory cytokinesNod-like receptor C1 (NLRC1)NOD-like receptor (NLR)HumanIntracellularC-terminal leucine-rich regions and NOD domainsNANANAtriggering production of β-defensins via an NF-κB signaling pathwayNA287764162017NA
PRRID_2363NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanthe apical and the basolateral pole of the gastric epitheliumLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA293306752017Pubchem_assay
PRRID_2363NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humanthe apical and the basolateral pole of the gastric epitheliumLeucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA293306752017Pubchem_assay
PRRID_2364NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 5 (TLR5)Toll-like receptor (TLR)Humanapical and basolateral surface in adult non-inflamed gastric epithelial cells but these receptors were localized exclusively to the basolateral surface in adults with H. pylori gastritisLeucine-rich Repeat (LRR) DomainO60602.fastaO60602858NANA293306752017Pubchem_assay
PRRID_2364NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 5 (TLR5)Toll-like receptor (TLR)Humanapical and basolateral surface in adult non-inflamed gastric epithelial cells but these receptors were localized exclusively to the basolateral surface in adults with H. pylori gastritisLeucine-rich Repeat (LRR) DomainO60602.fastaO60602858NANA293306752017Pubchem_assay
PRRID_2365NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanapical and basolateral surface in adult non-inflamed gastric epithelial cells but these receptors were localized exclusively to the basolateral surface in adults with H. pylori gastritisLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2365NA

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H. pylori (Bacteria)NANANANAH. pylori infection.Toll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanapical and basolateral surface in adult non-inflamed gastric epithelial cells but these receptors were localized exclusively to the basolateral surface in adults with H. pylori gastritisLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2374NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanmature villous epithelial cellsLeucine-rich Repeat (LRR) DomainQ99MB1.fastaQ99MB1905NANA293306752017Pubchem_assay
PRRID_2374NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanmature villous epithelial cellsLeucine-rich Repeat (LRR) DomainQ99MB1.fastaQ99MB1905NANA293306752017Pubchem_assay
PRRID_2375NA

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NANANANANANAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humancrypt epithelial cells,Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2375NA

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NANANANANANAToll-like receptor 2 (TLR2)Toll-like receptor (TLR)Humancrypt epithelial cells,Leucine-rich Repeat (LRR) DomainO60603.fastaO60603784NANA293306752017Pubchem_assay
PRRID_2376NA

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NANANANANANAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancrypt epithelial cells,Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA293306752017Pubchem_assay
PRRID_2376NA

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NANANANANANAToll-like receptor 4 (TLR4)Toll-like receptor (TLR)Humancrypt epithelial cells,Leucine-rich Repeat (LRR) DomainO00206.fastaO00206839NANA293306752017Pubchem_assay
PRRID_2380NA

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NANANANANANAToll-like receptor 1 (TLR1)Toll-like receptor (TLR)Humansecretory glands of the endocervixLeucine-rich Repeat (LRR) DomainQ15399.fastaQ15399786NANA293306752017Pubchem_assay
PRRID_2380NA

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NANANANANANAToll-like receptor 1 (TLR1)Toll-like receptor (TLR)Humansecretory glands of the endocervixLeucine-rich Repeat (LRR) DomainQ15399.fastaQ15399786NANA293306752017Pubchem_assay
PRRID_2381NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanintracellular in human cer- vical epithelial cellsLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904functionally responsive to their respective agonistsNA293306752017Pubchem_assay
PRRID_2381NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)Humanintracellular in human cer- vical epithelial cellsLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904functionally responsive to their respective agonistsNA293306752017Pubchem_assay
PRRID_2382NA

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NANANANANANAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanintracellular in human cer- vical epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032functionally responsive to their respective agonistsNA293306752017Pubchem_assay
PRRID_2382NA

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NANANANANANAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanintracellular in human cer- vical epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032functionally responsive to their respective agonistsNA293306752017Pubchem_assay
PRRID_2386NA

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NANANANANaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanepithelial cells of the penile urethraLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2386NA

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NANANANANaturalNAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)Humanepithelial cells of the penile urethraLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2387NA

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NANANANANANAToll-like receptor 1 (TLR1)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ15399.fastaQ15399786NANA293306752017Pubchem_assay
PRRID_2387NA

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NANANANANANAToll-like receptor 1 (TLR1)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ15399.fastaQ15399786NANA293306752017Pubchem_assay
PRRID_2388NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2388NA

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NANANANANANAToll-like receptor 3 (TLR3)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainO15455.fastaO15455904NANA293306752017Pubchem_assay
PRRID_2389NA

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NANANANANANAToll-like receptor 7 (TLR7)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NYK1.fastaQ9NYK11049NANA293306752017Pubchem_assay
PRRID_2389NA

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NANANANANANAToll-like receptor 7 (TLR7)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NYK1.fastaQ9NYK11049NANA293306752017Pubchem_assay
PRRID_2390NA

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NANANANANANAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2390NA

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NANANANANANAToll-like receptor 9 (TLR9)Toll-like receptor (TLR)HumanApical surface of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9NR96.fastaQ9NR961032NANA293306752017Pubchem_assay
PRRID_2391NA

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NANANANANANAToll-like receptor 6 (TLR6)Toll-like receptor (TLR)Humanintense basolateral staining of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9Y2C9.fastaQ9Y2C9796NANA293306752017Pubchem_assay
PRRID_2391NA

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NANANANANANAToll-like receptor 6 (TLR6)Toll-like receptor (TLR)Humanintense basolateral staining of tracheal epithelial cellsLeucine-rich Repeat (LRR) DomainQ9Y2C9.fastaQ9Y2C9796NANA293306752017Pubchem_assay