Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1441	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	100 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1442	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A375	7.0E+8 pfu	NA	Reduction in tumor volume after 7 weeks	Intratumoral	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1916	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viabilty after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1917	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1918	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1919	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	30% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1920	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1921	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1922	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	30% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1923	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	20% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1924	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viality after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1925	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1926	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	60% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1927	Adenovirus	SG600-IL24	DNA	Adenoviridae	Addition of gene encoding IL24	Yes	No	Virus expressing IL-24 gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	30% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1928	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viabilty after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1929	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1930	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1931	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	HepG2	1.0E+3 cells per well	NA	MTT assay	10 MOI	65% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1932	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viabilty after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1933	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1934	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1935	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	Hep3B	1.0E+3 cells per well	NA	MTT assay	10 MOI	65% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1936	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	90% cell viabilty after 24 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1937	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 48 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1938	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	80% cell viability after 72 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_1939	Adenovirus	SG600-EGFP	DNA	Adenoviridae	Addition of gene encoding EGFP	Yes	No	Virus expressing EGFP gene	Institute of HCC, Fudan university	Human liver cancer cell line	MHCC97L	1.0E+3 cells per well	NA	MTT assay	10 MOI	70% cell viability after 96 hours	No	No	NA	No response	NA	Virus induce the apoptosis in HCC cell line	NA	NA	20872968
OV_2065	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung cancer cell line	MRC-5	NA	NA	Crystal violet staining	0.1 MOI	No cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2066	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung cancer cell line	MRC-5	NA	NA	Crystal violet staining	1 MOI	No cell seath observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2067	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung cancer cell line	MRC-5	NA	NA	Crystal violet staining	10 MOI	No cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2068	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung cancer cell line	MRC-5	NA	NA	Crystal violet staining	100 MOI	Cell death observed	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2069	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung bronchi cell line	BEAS-2B	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2070	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung bronchi cell line	BEAS-2B	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2071	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung bronchi cell line	BEAS-2B	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2072	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung bronchi cell line	BEAS-2B	NA	NA	Crystal violet staining	100 MOI	All cells was dead	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2073	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	0.1 MOI	No cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2074	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2075	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	10 MOI	All cells was dead	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2076	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	100 MOI	All cells was dead	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2077	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2078	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	All cells was dead	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2079	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	All cells was dead	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2080	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	All cells was dead	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2081	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	No cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2082	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2083	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of senescence	NA	NA	21794078
OV_2084	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	All cells was dead	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2085	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.2 after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2086	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.2 after 48 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2087	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.2 after 72 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2088	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human cellosaurus cell line	BEL-7404	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.2 after 96 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2089	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.1 after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2090	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.1 after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2091	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.1 after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2092	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	MTT assay	1 MOI	Absorbance decrease to below 0.1 after 24 hours	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	21794078
OV_2093	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of shMPP1 expressing cassette	Yes	No	Virus expressing IL-24 gene	NA	Human colon cancer cell line	SW620	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for SW620 cell line (5.0E+6 cells)	2.0E+9 pfu	NA	Reduction in tumor volume below 100 mm after 9 weeks	NA	Induction of apoptosis	NA	NA	21794078
OV_2094	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2095	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2096	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2097	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	MRC-5	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2098	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2099	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2100	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2101	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2102	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2103	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2104	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2105	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2106	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2107	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2108	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2109	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2110	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2111	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2112	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2113	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2114	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2115	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2116	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	10 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2117	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of AFP gene	Yes	No	Virus expressing IL-24 gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2118	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	0.1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2119	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	1 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2120	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	10 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2121	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	L-02	NA	NA	Crystal violet staining	100 MOI	No cell killing	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2122	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2123	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2124	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2125	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human colon cancer cell line	SW620	NA	NA	Crystal violet staining	100 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2126	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2127	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2128	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2129	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human lung adenocarcinoma cell line	A549	NA	NA	Crystal violet staining	100 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2130	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2131	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2132	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2133	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2134	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	0.1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2135	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	1 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2136	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	10 MOI	Some cell death observed	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2137	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	HepG2	NA	NA	Crystal violet staining	100 MOI	Most of the cells are died	No	No	NA	No response	NA	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578
OV_2138	Adenovirus	Mutant	DNA	Adenoviridae	Deletion of E1BK55KD gene and addition of TRAIL gene	Yes	No	Virus expressing TRAIL gene	ATCC	Human hepatocellular carcinoma cell line	Huh-7	NA	NA	NA	NA	NA	BALB/c mice xenograft for Huh7 cell line (5.0E+6 Ã— 10â¶ pfu)	2.0E+9 pfu	NA	Significant reduction in tumor volume below 100mm and increase in median survival time after 57 days	Intratumoral	Induction of apoptosis in cancer as measured by TUNEL assay	NA	NA	21979578

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