Detailed description page of Selected OV_ID


OV_1930 details
Primary information
OV_IDOV_1930
Virus Name Adenovirus
StrainSG600-EGFP
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of gene encoding EGFP
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing EGFP gene
Source of cell lineInstitute of HCC, Fudan university
Origin of cell lineHuman liver cancer cell line
Cell lineHepG2
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result70% cell viability after 72 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce the apoptosis in HCC cell line
Immunogenic effectNA
Clinical trialNA
PMID20872968