Detailed description page of Selected OV_ID


OV_2090 details
Primary information
OV_IDOV_2090
Virus Name Adenovirus
StrainMutant
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1BK55KD gene and addition of shMPP1 expressing cassette
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineNA
Origin of cell lineHuman colon cancer cell line
Cell lineSW620
Concentration of cell line0
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration1 MOI
In-vitro resultAbsorbance decrease to below 0.1 after 24 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID21794078