Detailed description page of Selected OV_ID


OV_1917 details
Primary information
OV_IDOV_1917
Virus Name Adenovirus
StrainSG600-IL24
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeAddition of gene encoding IL24
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeVirus expressing IL-24 gene
Source of cell lineInstitute of HCC, Fudan university
Origin of cell lineHuman liver cancer cell line
Cell lineHepG2
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result70% cell viability after 48 hours
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionVirus induce the apoptosis in HCC cell line
Immunogenic effectNA
Clinical trialNA
PMID20872968