Browse By Oncolytic Virus Species Result Page of OvirusTdb
The Total number of records shown on this page is 81. Click on ID to see further detail.
IDOV_5744 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 604.3mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5745 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 914mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5746 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 962.1mm after 47 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5747 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1424.4mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5748 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1390.35mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5749 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 983.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5750 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1319.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5751 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1686.05mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5752 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 982mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5753 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 947.2mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5754 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1397.55mm after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5755 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1907.5mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5756 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1528.95mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5757 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 517.3mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5758 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1211.8mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5759 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1856.35mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5760 | Virus nameVaccinia virus | Virus strainGLV-1h84 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 614.25mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5761 | Virus nameVaccinia virus | Virus strainGLV-1h85 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 255.25mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5762 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 689.6mm after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5763 | Virus nameVaccinia virus | Virus strainGLV-1h22 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1887.6mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5764 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1181.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5765 | Virus nameVaccinia virus | Virus strainGLV-1h73 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 74.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5766 | Virus nameVaccinia virus | Virus strainGLV-1h82 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 855.9mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5767 | Virus nameVaccinia virus | Virus strainGLV-1h83 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP gene at place of HA gene under Psel promoter | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1392mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5768 | Virus nameVaccinia virus | Virus strainGLV-1h86 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 187.5mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5769 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 264.9mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5770 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 365.7mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5771 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 155.3mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5772 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 62mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5773 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 291.1mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5774 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 314.2mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5775 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 238.3mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5776 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (25mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 117.4mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5777 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 279.8mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5778 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 395.5mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5779 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 206.5mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5780 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (50mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 61mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5781 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 587.1mm compared to control 204.3 mm after 32 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5782 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 391.1mm compared to control 333.9 mm after 42 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5783 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 184mm compared to control 646.6 mm after 50 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5784 | Virus nameVaccinia virus | Virus strainGLV-1h74 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cidofovir (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume become 58mm compared to control 886.4 mm after 56 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5785 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 176.9 mm compared to control 278.1 after 53 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5786 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 598.8mm compared to control 755 after 63 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5787 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 668.4 mm compared to control 1169.9 after 69 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5788 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 896.6 mm compared to control 2512.7 after 77 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5789 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 298.8 after 41 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5790 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1448.3 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5791 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 2512.4 after 64 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5792 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 34.07 after 71 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5793 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 415.1 after 41 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5794 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1403.1 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5795 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 1163.7 after 64 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5796 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 993 after 71 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5797 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 757.5 after 79 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5798 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 667 after 87 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5799 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 547 after 93 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5800 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 549 after 99 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5801 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 511 after 106 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5802 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 465.3 after 113 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5803 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration2.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes 441.3 after 119 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5804 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 268.4 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5805 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 623.7 after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5806 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1232.5 after 70 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5807 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1277.05 after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5808 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1189.55 mm after 81 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5809 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 744.4mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5810 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 402.1 after 55 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5811 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1128.15 after 62 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5812 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1485.05 after 70 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5813 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume becomes to 1599.35 after 75 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5814 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1411.4mm after 81 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5815 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1040mm after 89 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5816 | Virus nameVaccinia virus | Virus strainGLV-1h68 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationInsertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with cisplatin (5mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismHsd athymic nude mice xenograft for OVCAR-3 (5.0E+6) | In-vivo virus concentration5.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 906.75 mm after 96 days | Mode of deliveryIntravenously | Pathway inducedInduction of apoptosis | Immunogenic effectNA | Clinical trialNA | PMIDUS8052968 |
IDOV_5885 | Virus nameVaccinia virus | Virus strainMutant | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant in F2L gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5FC(100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenograft for LoVo cell | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1000mm compared to control 2500mm after 40 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9180150 |
IDOV_5886 | Virus nameVaccinia virus | Virus strainMutant | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationMutant in F2L gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5FC(100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismNude mice xenograft for HepG2 | In-vivo virus concentration1.0E+6 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to 1000mm compared to control 2500mm after 40 days | Mode of deliveryIntratumoral | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9180150 |
IDOV_5896 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman colon tumor cell line | Cell lineLoVo | Concentration of cell line3.0E+5 pfu | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.00001 MOI | In-vitro result60% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |
IDOV_5897 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman colon tumor cell line | Cell lineLoVo | Concentration of cell line3.0E+5 pfu | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.00001 MOI | In-vitro result58% of cancer cell death occurs | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |
IDOV_5898 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismSwiss nude mice xenograft for LoVo cell line (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to nearly 1000mm compared to control 2400mm | Mode of deliveryIntravenously | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |
IDOV_5899 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in F4L gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismSwiss nude mice xenograft for LoVo cell line (5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 1000mm compared to control 2400mm | Mode of deliveryIntravenously | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |
IDOV_5900 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismSwiss nude mice xenograft for U87MG(5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 500mm comapred to control 3500mm after 60 days | Mode of deliveryIntravenously | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |
IDOV_5901 | Virus nameVaccinia virus | Virus strainVVTK-FCU1 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDefective in J2R gene, expressing FCU1 gene, defective in I4L gene | Virus aloneNo | Virus in combination with drug/radiationVirus in combination with 5FU (100mg/kg) | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineNA | Cell lineNA | Concentration of cell lineNA | In-vitro toxicityNA | AssayNA | In-vitro virus concentrationNA | In-vitro resultNA | Model organismSwiss nude mice xenograft for U87MG(5.0E+6) | In-vivo virus concentration1.0E+7 pfu | In-vivo toxicityNA | In-vivo resultTumor volume reduced to below 500mm comapred to control 3500mm after 60 days | Mode of deliveryIntravenously | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMIDUS9687515 |