Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 81. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_5744	Vaccinia virus	GLV-1h84	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 604.3mm after 47 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5745	Vaccinia virus	GLV-1h85	DNA	Poxviridae	Insertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 914mm after 47 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5746	Vaccinia virus	GLV-1h86	DNA	Poxviridae	Insertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 962.1mm after 47 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5747	Vaccinia virus	GLV-1h22	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1424.4mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5748	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1390.35mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5749	Vaccinia virus	GLV-1h73	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 983.2mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5750	Vaccinia virus	GLV-1h82	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1319.2mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5751	Vaccinia virus	GLV-1h83	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1686.05mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5752	Vaccinia virus	GLV-1h84	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 982mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5753	Vaccinia virus	GLV-1h85	DNA	Poxviridae	Insertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 947.2mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5754	Vaccinia virus	GLV-1h86	DNA	Poxviridae	Insertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1397.55mm after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5755	Vaccinia virus	GLV-1h22	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1907.5mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5756	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1528.95mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5757	Vaccinia virus	GLV-1h73	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 517.3mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5758	Vaccinia virus	GLV-1h82	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1211.8mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5759	Vaccinia virus	GLV-1h83	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1856.35mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5760	Vaccinia virus	GLV-1h84	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of F14.5L gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 614.25mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5761	Vaccinia virus	GLV-1h85	DNA	Poxviridae	Insertion of noncoding DNA into F14.5L gene, TK gene at place of LacZ and gusA gene at place of HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 255.25mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5762	Vaccinia virus	GLV-1h86	DNA	Poxviridae	Insertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 689.6mm after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5763	Vaccinia virus	GLV-1h22	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1887.6mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5764	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vectorrespectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1181.4mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5765	Vaccinia virus	GLV-1h73	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, LacZ gene at TK gene, noncoding DNA into HA locus	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 74.4mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5766	Vaccinia virus	GLV-1h82	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 855.9mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5767	Vaccinia virus	GLV-1h83	DNA	Poxviridae	Insertion of Ruc-GFP gene at place of HA gene under Psel promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 1392mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5768	Vaccinia virus	GLV-1h86	DNA	Poxviridae	Insertion of Ruc-GFP into F14.5L gene, noncoding DNA at place of LacZ and HA gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes 187.5mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5769	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 264.9mm compared to control 204.3 mm after 32 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5770	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 365.7mm compared to control 333.9 mm after 42 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5771	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 155.3mm compared to control 646.6 mm after 50 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5772	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 62mm compared to control 886.4 mm after 56 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5773	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (25mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 291.1mm compared to control 204.3 mm after 32 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5774	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (25mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 314.2mm compared to control 333.9 mm after 42 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5775	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (25mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 238.3mm compared to control 646.6 mm after 50 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5776	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (25mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 117.4mm compared to control 886.4 mm after 56 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5777	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (50mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 279.8mm compared to control 204.3 mm after 32 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5778	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (50mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 395.5mm compared to control 333.9 mm after 42 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5779	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (50mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 206.5mm compared to control 646.6 mm after 50 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5780	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (50mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 61mm compared to control 886.4 mm after 56 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5781	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 587.1mm compared to control 204.3 mm after 32 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5782	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 391.1mm compared to control 333.9 mm after 42 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5783	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 184mm compared to control 646.6 mm after 50 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5784	Vaccinia virus	GLV-1h74	DNA	Poxviridae	Insertion of noncoding DNA at F14.5 locus, noncoding DNA at TK locus and HA gene locus in gusA	No	Virus in combination with cidofovir (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for GI-101A human breast carcinoma cells (5.0E+6)	5.0E+6 pfu	NA	Tumor volume become 58mm compared to control 886.4 mm after 56 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5785	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 176.9 mm compared to control 278.1 after 53 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5786	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 598.8mm compared to control 755 after 63 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5787	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 668.4 mm compared to control 1169.9 after 69 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5788	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to 896.6 mm compared to control 2512.7 after 77 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5789	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 298.8 after 41 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5790	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 1448.3 after 55 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5791	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 2512.4 after 64 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5792	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 34.07 after 71 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5793	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 415.1 after 41 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5794	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 1403.1 after 55 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5795	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 1163.7 after 64 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5796	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 993 after 71 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5797	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 757.5 after 79 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5798	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 667 after 87 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5799	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 547 after 93 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5800	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 549 after 99 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5801	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 511 after 106 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5802	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 465.3 after 113 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5803	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	2.0E+6 pfu	NA	Tumor volume becomes 441.3 after 119 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5804	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 268.4 after 55 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5805	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 623.7 after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5806	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 1232.5 after 70 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5807	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 1277.05 after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5808	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume reduced to 1189.55 mm after 81 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5809	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume reduced to 744.4mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5810	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 402.1 after 55 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5811	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 1128.15 after 62 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5812	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 1485.05 after 70 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5813	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume becomes to 1599.35 after 75 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5814	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume reduced to 1411.4mm after 81 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5815	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume reduced to 1040mm after 89 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5816	Vaccinia virus	GLV-1h68	DNA	Poxviridae	Insertion of Ruc-GFP, non coding DNA at F14.5L gene locus and TK and HA gene locus using psel vector respectively	No	Virus in combination with cisplatin (5mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Hsd athymic nude mice xenograft for OVCAR-3 (5.0E+6)	5.0E+6 pfu	NA	Tumor volume reduced to 906.75 mm after 96 days	Intravenously	Induction of apoptosis	NA	NA	US8052968
OV_5885	Vaccinia virus	Mutant	DNA	Poxviridae	Mutant in F2L gene	No	Virus in combination with 5FC(100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Nude mice xenograft for LoVo cell	1.0E+6 pfu	NA	Tumor volume reduced to 1000mm compared to control 2500mm after 40 days	Intratumoral	NA	NA	NA	US9180150
OV_5886	Vaccinia virus	Mutant	DNA	Poxviridae	Mutant in F2L gene	No	Virus in combination with 5FC(100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Nude mice xenograft for HepG2	1.0E+6 pfu	NA	Tumor volume reduced to 1000mm compared to control 2500mm after 40 days	Intratumoral	NA	NA	NA	US9180150
OV_5896	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene	Yes	No	No	NA	Human colon tumor cell line	LoVo	3.0E+5 pfu	NA	MTT assay	0.00001 MOI	60% of cancer cell death occurs	No	No	NA	No response	NA	NA	NA	NA	US9687515
OV_5897	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in I4L gene	Yes	No	No	NA	Human colon tumor cell line	LoVo	3.0E+5 pfu	NA	MTT assay	0.00001 MOI	58% of cancer cell death occurs	No	No	NA	No response	NA	NA	NA	NA	US9687515
OV_5898	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in I4L gene	No	Virus in combination with 5FU (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Swiss nude mice xenograft for LoVo cell line (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to nearly 1000mm compared to control 2400mm	Intravenously	NA	NA	NA	US9687515
OV_5899	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in F4L gene	No	Virus in combination with 5FU (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Swiss nude mice xenograft for LoVo cell line (5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to below 1000mm compared to control 2400mm	Intravenously	NA	NA	NA	US9687515
OV_5900	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in I4L gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Swiss nude mice xenograft for U87MG(5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to below 500mm comapred to control 3500mm after 60 days	Intravenously	NA	NA	NA	US9687515
OV_5901	Vaccinia virus	VVTK-FCU1	DNA	Poxviridae	Defective in J2R gene, expressing FCU1 gene, defective in I4L gene	No	Virus in combination with 5FU (100mg/kg)	No	NA	NA	NA	NA	NA	NA	NA	NA	Swiss nude mice xenograft for U87MG(5.0E+6)	1.0E+7 pfu	NA	Tumor volume reduced to below 500mm comapred to control 3500mm after 60 days	Intravenously	NA	NA	NA	US9687515

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