Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1310	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	No significant effect on cell death after day 1	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1311	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	No significant effect on cell death after day 2	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1312	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	No significant effect on cell death after day 3	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1313	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	ATCC	Human prostate cancer cell line	PrEC	1000 cells per well	NA	Cell proliferation kit by Roche Diagnostics	10 MOI	No significant effect on cell death after day 4	No	No	NA	No response	NA	NA	NA	NA	18274558
OV_1314	Adenovirus	OBP-301	DNA	Adenoviridae	None	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for Human prostate cancer cell line LNCaP	1.0E+7 pfu	NA	Reduction in tumor size after day 20, 3 times administration	Intratumoral	NA	NA	NA	18274558
OV_1315	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1316	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1317	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1318	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1319	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1320	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1321	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1322	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1323	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1324	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1325	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.01 MOI	some cells are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1326	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	0.1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1327	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	1 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1328	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	10 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1329	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	ATCC	Human hepatocellular carcinoma cell line	Hep3B	NA	NA	Crystal violet staining	100 MOI	100% cancer cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1330	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1331	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1332	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1333	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1334	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1335	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1336	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1337	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1338	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1339	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1340	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.01 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1341	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	0.1 MOI	Some cell are viable	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1342	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1343	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1344	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1345	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	50% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1346	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	50% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1347	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	BEL-7404	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1348	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1349	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1350	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	Shanghai institute for biological scinces	Human hepatocellular carcinoma cell line	SMMC7721	NA	NA	Crystal violet staining	100MOI	30% cell killing after 96 hours	No	No	NA	No response	NA	NA	NA	NA	18281783
OV_1351	Adenovirus	AdCN101	DNA	Adenoviridae	24bp deletion between E1Ap and E1A	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice, xenograft for BEL7404	2.0E+8 pfu	NA	Significant reduction in tumor volume after 7 weeks and increase in survival	Intratumoral	NA	NA	NA	18281783
OV_1352	Adenovirus	AdCN102	DNA	Adenoviridae	Addition of hTERT promoter ahead of E1A	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice, xenograft for BEL7404	2.0E+8 pfu	NA	Significant reduction in tumor volume after 7 weeks and increase in survival	Intratumoral	NA	NA	NA	18281783
OV_1353	Adenovirus	AdCN103	DNA	Adenoviridae	24 bp deletion in hTERT promoter	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice, xenograft for BEL7404	2.0E+8 pfu	NA	Significant reduction in tumor volume after 7 weeks and increase in survival	Intratumoral	NA	NA	NA	18281783
OV_1354	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1355	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	90% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1356	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	1 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1357	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	10 MOI	20% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1358	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	100 MOI	less than 20% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1359	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	HepG2	1.0E+4 cells per well	NA	MTT assay	1000 MOI	less than 20% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1360	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1361	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	0.1 MOI	30% cell survival	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1362	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	1 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1363	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1364	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	100 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1365	Adenovirus	CNHK300	DNA	Adenoviridae	None	Yes	No	No	ATCC	Hepatocellular carcinoma cell line	Hep3B	1.0E+4 cells per well	NA	MTT assay	1000 MOI	100% cell killing	No	No	NA	No response	NA	NA	NA	NA	18300357
OV_1366	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	0.01 MOI	Cancer cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1367	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	0.1 MOI	Cancer cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1368	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1369	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1370	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1371	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	0.01 MOI	Cancer cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1372	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	0.1 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1373	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	1 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1374	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	10 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1375	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	100 MOI	100% cell killing	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1376	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	85% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1377	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	MTT assay	1 MOI	75% cell survival after day 2	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1378	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	MTT assay	10 MOI	60% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1379	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	MTT assay	100 MOI	40% cell survival after day 4	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1380	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	786	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	100% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1381	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	MTT assay	1 MOI	90% cell survival after day 2	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1382	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	MTT assay	10 MOI	60% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1383	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	Shanghai cell collection	Human renal cacinoma cell line	ACHN	1.0E+5 cells per well	NA	MTT assay	100 MOI	20% cell survival after day 4	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	18690204
OV_1384	Adenovirus	ZD55-Ki67	DNA	Adenoviridae	Expressing Ki67 ShRNA	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c nude mice xenograft for Human prostate cancer cell line LNCaP	7.0E+8 cells per well	NA	Significant reduction in tumor size after 9 weeks	Intratumoral	Induction of apoptosis	NA	NA	18690204
OV_1385	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	Crystal violet staining	0.1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1386	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	Crystal violet staining	1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1387	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	Crystal violet staining	10 MOI	some cells are viable after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1388	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	Crystal violet staining	100 MOI	All cells are killed after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1389	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	0.1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1390	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1391	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	10 MOI	some cells are viable after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1392	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	786	1.0E+5 cells per well	NA	Crystal violet staining	100 MOI	All cells are killed after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1393	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	0.1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1394	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	1 MOI	100% cell survival after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1395	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	10 MOI	some cells are viable after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1396	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	ACHN	1.0E+5 cells per well	NA	Crystal violet staining	100 MOI	All cells are killed after day 7	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1397	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	10 MOI	90% cell survival after day 1	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1398	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	10 MOI	50% cell survival after day 2	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1399	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	10 MOI	45% cell survival after day 3	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1400	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	10 MOI	30% cell survival after day 4	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1401	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	0.1 MOI	90% cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1402	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	1 MOI	60% cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1403	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	10 MOI	30% cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1404	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	Shanghai cell collection	Renal cancer cell line	Ketr-3	1.0E+5 cells per well	NA	MTT assay	100 MOI	20% cell survival	No	No	NA	No response	NA	Induction of apoptosis	NA	NA	19029834
OV_1405	Adenovirus	ZD55-hTERT	DNA	Adenoviridae	Deletion of E1B gene and addition of shRNA expressing hTERT	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/ c nude mice injected for Ketr-3 cell line	7.0E+8 cells per well	NA	Significant reduction in tumor size after 7 weeks	Subcutaneous	Induction of apoptosis	NA	NA	19029834
OV_1437	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	0.01 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1438	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	0.1 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1439	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	1 MOI	Cell survival observerd	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459
OV_1440	Adenovirus	ZD-55-IL-18	DNA	Adenoviridae	None	Yes	No	Virus expressing IL-18 gene	Shanghai cell collection	Human melanoma cell line	A375	NA	NA	Crystal violet staining	10 MOI	100% cell death	No	No	NA	No response	NA	Induction of apoptosis, activation of caspase 3	NA	NA	19498459

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