| Primary information |
|---|
| OV_ID | OV_1437 |
| Virus Name | Adenovirus |
| Strain | ZD-55-IL-18 |
| Virus type | DNA |
| Virus family | Adenoviridae |
| Modification in virus genome | None |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | Virus expressing IL-18 gene |
| Source of cell line | Shanghai cell collection |
| Origin of cell line | Human melanoma cell line |
| Cell line | A375 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | Crystal violet staining |
| In-vitro virus concentration | 0.01 MOI |
| In-vitro result | Cell survival observerd |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | Induction of apoptosis, activation of caspase 3 |
| Immunogenic effect | NA |
| Clinical trial | NA |
| PMID | 19498459 |