Detailed description page of Selected OV_ID


OV_1384 details
Primary information
OV_IDOV_1384
Virus Name Adenovirus
StrainZD55-Ki67
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeExpressing Ki67 ShRNA
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineNA
Origin of cell lineNA
Cell lineNA
Concentration of cell line0
In-vitro toxicityNA
AssayNA
In-vitro virus concentrationNA
In-vitro resultNA
Model organismBALB/c nude mice xenograft for Human prostate cancer cell line LNCaP
In-vivo virus concentration7 × 10⁸cells per well
In-vivo toxicityNA
In-vivo resultSignificant reduction in tumor size after 9 weeks
Mode of deliveryIntratumoral
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID18690204