Detailed description page of Selected OV_ID


OV_1400 details
Primary information
OV_IDOV_1400
Virus Name Adenovirus
StrainZD55-hTERT
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeDeletion of E1B gene and addition of shRNA expressing hTERT
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineShanghai cell collection
Origin of cell lineRenal cancer cell line
Cell lineKetr-3
Concentration of cell line1
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration10 MOI
In-vitro result30% cell survival after day 4
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionInduction of apoptosis
Immunogenic effectNA
Clinical trialNA
PMID19029834