Browse By Oncolytic Virus Species Result Page of OvirusTdb

The Total number of records shown on this page is 100. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_4519	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	30% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4520	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	35% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4521	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	18% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4522	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.001mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4523	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.0025mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4524	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with 4-HP-CP (0.005mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	15% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4525	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	100% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4526	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	90% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4527	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1 VP/cell	80% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4528	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	80% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4529	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	70% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4530	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	10 VP/cell	62% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4531	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4532	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4533	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	100 VP/cell	40% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4534	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4535	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.0075mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4536	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with Cyclophosphamide (0.05mg/ml)	No	ATCC	Human breast cancer triple negative cell line	MDA-MB-436	1000 cells per well	NA	MTS assay	1000 VP/cell	20% cancer cell survival after 5 days	No	No	NA	No response	NA	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4537	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	Female nude NMRI mice xenograft for MDA-MB-436 (5.0E+6)	7.0E+9 pfu on day 1,4,8,15,29 and 43	NA	Tumor volume reduced to 1400 cubic mm after 36 days compared to contro 2200 cubic mm	Intratumoral	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4538	Adenovirus	Ad5/3-D24-GMCSF	DNA	Adenoviridae	Ad5/3-delta24 has a 24 base-pair deletion in constant region 2 of the E1A gene and armed wirh human GMCSF	No	Virus in combination with cyclophospahamide (20mg/kg), intraperionoeal	No	NA	NA	NA	NA	NA	NA	NA	NA	Female nude NMRI mice xenograft for MDA-MB-436 (5.0E+6)	7.0E+9 pfu on day 1,4,8,15,29 and 43	NA	Tumor volume reduced to 200 cubic mm after 61 days compared to contro 2200 cubic mm	Intratumoral	NA	Virus induced tumor specific T-cell response	NA	27057453
OV_4539	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4540	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	97% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4541	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	97% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4542	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4543	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4544	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4545	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4546	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	72% cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4547	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	72% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4548	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4549	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4550	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	50% cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4551	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	40% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4552	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	42% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4553	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	42% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4554	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	A549	5.0E+4 cells per well	NA	MTT assay	10 MOI	35% cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4555	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cancer cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4556	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4557	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4558	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cancer cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4559	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4560	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4561	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4562	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4563	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4564	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4565	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4566	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4567	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	78% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4568	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4569	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4570	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H460	5.0E+4 cells per well	NA	MTT assay	10 MOI	62% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4571	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4572	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4573	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4574	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4575	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4576	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4577	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	82% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4578	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	72% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4579	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	70% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4580	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	70% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4581	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	62% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4582	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	50% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4583	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4584	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	60% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4585	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	58% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4586	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1299	5.0E+4 cells per well	NA	MTT assay	10 MOI	42% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4587	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4588	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4589	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4590	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cell survival after 24 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4591	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4592	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4593	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	100% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4594	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	90% cancer cell survival after 48 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4595	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4596	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4597	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4598	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	70% cancer cell survival after 72 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4599	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4600	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4601	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	80% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4602	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	Shanghai cell collection	Human lung carcinoma cell line	NCI-H1975	5.0E+4 cells per well	NA	MTT assay	10 MOI	70% cancer cell survival after 96 hours	No	No	NA	No response	NA	Virus induced apoptosis	NA	NA	27080225
OV_4603	Adenovirus	CD55-MnSOD	DNA	Adenoviridae	virus containing MnSOD gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 300 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4604	Adenovirus	CD55-TRAIL	DNA	Adenoviridae	virus containing TRAIL gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 220 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4605	Adenovirus	CD55-TRAIL+ CD55-MnSOD	DNA	Adenoviridae	virus containing TRAIl and MnSOD gene	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to 200 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4606	Adenovirus	CD55-TRAIL-IETD-MnSOD	DNA	Adenoviridae	Virus having TRAIL, MnSOD gene linked via IETD caspase 8 cleavage site	Yes	No	No	NA	NA	NA	NA	NA	NA	NA	NA	BALB/c mice xenograft for A549 cell (5.0E+6)	5.0E+8 pfu	NA	Tumor volume reduced to below 100 cubic mm comapred to control 700 cubic mm after 40 days	Intratumoral	Virus induced apoptosis	NA	NA	27080225
OV_4607	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4608	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4609	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	70% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4610	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4611	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	50% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4612	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	10% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4613	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	70% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4614	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	58 cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4615	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	10% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4616	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4617	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4618	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	VU university medical centre, Netherland	Human neck and squamous cell carcinoma cell line	93VU147T	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483

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