Primary information |
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OV_ID | OV_4587 |
Virus Name | Adenovirus |
Strain | CD55-TRAIL+ CD55-MnSOD |
Virus type | DNA |
Virus family | Adenoviridae |
Modification in virus genome | virus containing TRAIl and MnSOD gene |
Virus alone | Yes |
Virus in combination iwth drug/radiation | No |
Immune gene induction in virus genome | No |
Source of cell line | Shanghai cell collection |
Origin of cell line | Human lung carcinoma cell line |
Cell line | NCI-H1975 |
Concentration of cell line | 5 |
In-vitro toxicity | NA |
Assay | MTT assay |
In-vitro virus concentration | 10 MOI |
In-vitro result | 100% cell survival after 24 hours |
Model organism | No |
In-vivo virus concentration | No |
In-vivo toxicity | NA |
In-vivo result | No response |
Mode of delivery | NA |
Pathway induction | Virus induced apoptosis |
Immunogenic effect | NA |
Clinical trial | NA |
PMID | 27080225 |