The total number of records retrieved from this search are 91. Click on ID to see further detail.

ID	Virus name	Virus strain	Virus genome type	Virus family	Virus genome modification	Virus alone	Virus in combination with drug/radiation	Immune gene insertion in viral genome	Source of cell line	Origin of cell line	Cell line	Concentration of cell line	In-vitro toxicity	Assay	In-vitro virus concentration	In-vitro result	Model organism	In-vivo virus concentration	In-vivo toxicity	In-vivo result	Mode of delivery	Pathway induced	Immunogenic effect	Clinical trial	PMID
OV_1246	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	No cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1247	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	80% cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1248	Vesicular stomatitis virus	wild type	RNA	Rhabdoviridae	Yes	No	VSV in combination with cisplatin (0.1 microgram/ml)	Virus expressing IL-12 gene	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1249	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	10% cancer cell killing after 24 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1250	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cancer cell killing after 48 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1251	Vesicular stomatitis virus	Fusogenic strain	RNA	Rhabdoviridae	Yes , expressing fusion protein	No	VSV in combination with cisplatin (0.1 microgram/ml)	No	Richard wong lab	squamous cell carcinoma cell line	SCCVII	5.0E+4 cells per well	NA	MTT assay	0.01 MOI	100% cancer cell killing after 72 hours	No	No	NA	No response	NA	NA	NA	NA	18043494
OV_1599	Sindbis virus	AR339	RNA	Hantaviridae	None	Yes	No	No	Human Science Research Resource Bank, Japan	Oral squamous cell line	SCC-4	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	60% cell are viable after 96 hours	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	19638980
OV_1612	Sindbis virus	AR339	RNA	Hantaviridae	None	Yes	No	No	Human Science Research Resource Bank, Japan	Oral squamous cell line	SCC-4	1.0E+5 cells per well	NA	Luminiscence measurement	0.01 MOI	45% cells are viable after 96 hours	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	19638980
OV_1625	Sindbis virus	AR339	RNA	Hantaviridae	None	Yes	No	No	Human Science Research Resource Bank, Japan	Oral squamous cell line	SCC-4	1.0E+5 cells per well	NA	Luminiscence measurement	1 MOI	35% cells are viable after 96 hours	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	19638980
OV_1638	Sindbis virus	AR339	RNA	Hantaviridae	None	Yes	No	No	Human Science Research Resource Bank, Japan	Oral squamous cell line	SCC-4	1.0E+5 cells per well	NA	Luminiscence measurement	20 MOI	2% dells are viable after 96 hours	No	No	NA	No response	NA	Induction of apoptosis as measured by TUNEL assay	NA	NA	19638980
OV_2427	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2428	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2429	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	100% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2430	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	50% cell killing after day 7	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2431	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.01 MOI	60% cell killing after day 9	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2467	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	100% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2468	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	90% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2469	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	50% cell survival after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2470	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	40% cell survival after day 7	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2471	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	0.10 MOI	30% cell survival after day 9	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2504	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	50% cell survival after day 1	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2505	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	20% cell survival after day 3	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2506	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	100% cell death after day 5	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2507	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	100% cell death after day 7	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2508	Vaccinia virus	GLV-1h151	DNA	Poxviridae	Deteltion of TK gene and addition of GFP gene	Yes	No	No	ATCC	Human squamous cell line	SCC-25	3.0E+4 cells per well	NA	LDH release and spectrophometer	1 MOI	100% cell death after day 9	No	No	NA	No response	NA	NA	NA	NA	22258815
OV_2977	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	SCC-9	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	33.2 +/- 9.9% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2978	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	SCC-25	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	54.6 +/- 21.5% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2979	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-38	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	83.9 +/- 16.3% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2980	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-47	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	97.2 +/- 4.7% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_2981	Reovirus	wild type	RNA	Reoviridae	None	Yes	No	No	ATCC	Human neck and squamous carcinoma cell line	UM-SCC-104	7.68E+3 cells per well	NA	Alamar blue assay	2.4 × 10⁸ pfu	82.3 +/- 6.5% cell viable after 96 hours	No	No	NA	No response	NA	NA	NA	NA	25890191
OV_4483	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	70% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4484	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	60% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4485	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	10 MOI	50% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4486	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	50% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4487	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	40% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4488	Herpes simplex virus	RH2	DNA	Herpesviridae	Mutant for Gamma 34.5 gene and gB gene	Yes	No	No	NA	Murine squamous cell carcinoma	SCCVII	NA	NA	MTT assay	100 MOI	30% cell survival after 12 hours	No	No	NA	No response	NA	Virus induced apoptosis	Increased extracellular ATP and HMGB1, indicating immunogenic cell death	NA	26987291
OV_4619	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4620	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4621	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4622	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4623	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4624	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	40% cell viablity after 3 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4625	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	80% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4626	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	80% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4627	Adenovirus	Ad5/3-CB016	DNA	Adenoviridae	Mutation in delta E3 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	70% cell viablity after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4628	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	1 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4629	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	10 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4630	Adenovirus	Ad5/3-delata 24	DNA	Adenoviridae	Mutation in delta E3 and delta 24 gene	Yes	No	No	University of pitsburgh	Human neck and squamous cell carcinoma cell line	UPCI SCC 090	3000 cells per well	NA	MTT assay	100 VP per cell	100% cell killing after 7 days	No	No	NA	No response	NA	NA	NA	NA	27086483
OV_4663	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.001 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4664	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.005 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4665	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.01 MOI	55% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4666	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.05 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4667	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4668	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	0.5 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4669	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-47	NA	NA	Statistical analysis	1 MOI	30% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4670	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.001 MOI	100% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4671	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.005 MOI	95% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4672	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.01 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4673	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.05 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4674	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.1 MOI	25% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4675	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	0.5 MOI	22% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4676	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UD-SCC-2	NA	NA	Statistical analysis	1 MOI	20% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4677	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4678	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.005 MOI	70% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4679	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.01 MOI	65% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4680	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.05 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4681	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.1 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4682	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	0.5 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4683	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-74A	NA	NA	Statistical analysis	1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4684	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4685	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.005 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4686	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.01 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4687	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.05 MOI	60% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4688	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.1 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4689	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	0.5 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4690	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-1	NA	NA	Statistical analysis	1 MOI	38% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4691	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.001 MOI	90% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4692	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.005 MOI	82% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4693	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.01 MOI	76% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4694	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.05 MOI	62% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4695	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.1 MOI	62% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4696	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	0.5 MOI	50% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4697	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	Yes	No	No	NA	Human squamous cell carcinoma cell line	UM-SCC-11A	NA	NA	Statistical analysis	1 MOI	40% cell viability after 2 days	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4699	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-74A	NA	NA	Crystal violet staining	0.5 MOI	38% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4701	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-1	NA	NA	Crystal violet staining	0.5 MOI	40% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4702	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-2	NA	NA	Crystal violet staining	0.5 MOI	45% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_4703	Herpes simplex virus	RAMBO	DNA	Herpesviridae	Antiangiogenic Vstat120 expressing virus	No	Virus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy	No	NA	Human squamous cell carcinoma cell line	SCC-11A	NA	NA	Crystal violet staining	0.5 MOI	38% cell viability	No	No	NA	No response	NA	NA	Induce antitumor immune response	NA	27119105
OV_5906	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	60% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5907	Newcastle disease virus	NDV-B1	RNA	Paramyxoviridae	None	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	No cell death observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5908	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	100% cell killing observed after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984
OV_5909	Newcastle disease virus	NDV-F3aa	RNA	Paramyxoviridae	Virus expressing NS1 protein	Yes	No	No	ATCC	Human neck and head carcinoma cell line	SCC	5E+5 pfu	NA	LDH release assay	0.1 MOI	70% cell killing after 3 days	No	No	NA	No response	NA	NA	Virus induced IFN-gamma production	NA	US10035984