Browse By Cell Line Result Page of OvirusTdb
The total number of records retrieved from this search are 91. Click on ID to see further detail.
IDOV_1246 | Virus nameVesicular stomatitis virus | Virus strainwild type | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeVirus expressing IL-12 gene | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro resultNo cell killing after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1247 | Virus nameVesicular stomatitis virus | Virus strainwild type | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeVirus expressing IL-12 gene | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result80% cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1248 | Virus nameVesicular stomatitis virus | Virus strainwild type | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeVirus expressing IL-12 gene | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1249 | Virus nameVesicular stomatitis virus | Virus strainFusogenic strain | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes , expressing fusion protein | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeNo | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result10% cancer cell killing after 24 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1250 | Virus nameVesicular stomatitis virus | Virus strainFusogenic strain | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes , expressing fusion protein | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeNo | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cancer cell killing after 48 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1251 | Virus nameVesicular stomatitis virus | Virus strainFusogenic strain | Virus genome typeRNA | Virus familyRhabdoviridae | Virus genome modificationYes , expressing fusion protein | Virus aloneNo | Virus in combination with drug/radiationVSV in combination with cisplatin (0.1 microgram/ml) | Immune gene insertion in viral genomeNo | Source of cell lineRichard wong lab | Origin of cell linesquamous cell carcinoma cell line | Cell lineSCCVII | Concentration of cell line5.0E+4 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration0.01 MOI | In-vitro result100% cancer cell killing after 72 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID18043494 |
IDOV_1599 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyHantaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineHuman Science Research Resource Bank, Japan | Origin of cell lineOral squamous cell line | Cell lineSCC-4 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayLuminiscence measurement | In-vitro virus concentration0.01 MOI | In-vitro result60% cell are viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID19638980 |
IDOV_1612 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyHantaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineHuman Science Research Resource Bank, Japan | Origin of cell lineOral squamous cell line | Cell lineSCC-4 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayLuminiscence measurement | In-vitro virus concentration0.01 MOI | In-vitro result45% cells are viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID19638980 |
IDOV_1625 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyHantaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineHuman Science Research Resource Bank, Japan | Origin of cell lineOral squamous cell line | Cell lineSCC-4 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayLuminiscence measurement | In-vitro virus concentration1 MOI | In-vitro result35% cells are viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID19638980 |
IDOV_1638 | Virus nameSindbis virus | Virus strainAR339 | Virus genome typeRNA | Virus familyHantaviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineHuman Science Research Resource Bank, Japan | Origin of cell lineOral squamous cell line | Cell lineSCC-4 | Concentration of cell line1.0E+5 cells per well | In-vitro toxicityNA | AssayLuminiscence measurement | In-vitro virus concentration20 MOI | In-vitro result2% dells are viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedInduction of apoptosis as measured by TUNEL assay | Immunogenic effectNA | Clinical trialNA | PMID19638980 |
IDOV_2427 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2428 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2429 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result100% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2430 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result50% cell killing after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2431 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.01 MOI | In-vitro result60% cell killing after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2467 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result100% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2468 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result90% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2469 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result50% cell survival after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2470 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result40% cell survival after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2471 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration0.10 MOI | In-vitro result30% cell survival after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2504 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result50% cell survival after day 1 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2505 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result20% cell survival after day 3 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2506 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 5 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2507 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 7 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2508 | Virus nameVaccinia virus | Virus strainGLV-1h151 | Virus genome typeDNA | Virus familyPoxviridae | Virus genome modificationDeteltion of TK gene and addition of GFP gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman squamous cell line | Cell lineSCC-25 | Concentration of cell line3.0E+4 cells per well | In-vitro toxicityNA | AssayLDH release and spectrophometer | In-vitro virus concentration1 MOI | In-vitro result100% cell death after day 9 | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID22258815 |
IDOV_2977 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and squamous carcinoma cell line | Cell lineSCC-9 | Concentration of cell line7.68E+3 cells per well | In-vitro toxicityNA | AssayAlamar blue assay | In-vitro virus concentration2.4 × 10⸠pfu | In-vitro result33.2 +/- 9.9% cell viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID25890191 |
IDOV_2978 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and squamous carcinoma cell line | Cell lineSCC-25 | Concentration of cell line7.68E+3 cells per well | In-vitro toxicityNA | AssayAlamar blue assay | In-vitro virus concentration2.4 × 10⸠pfu | In-vitro result54.6 +/- 21.5% cell viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID25890191 |
IDOV_2979 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and squamous carcinoma cell line | Cell lineUM-SCC-38 | Concentration of cell line7.68E+3 cells per well | In-vitro toxicityNA | AssayAlamar blue assay | In-vitro virus concentration2.4 × 10⸠pfu | In-vitro result83.9 +/- 16.3% cell viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID25890191 |
IDOV_2980 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and squamous carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell line7.68E+3 cells per well | In-vitro toxicityNA | AssayAlamar blue assay | In-vitro virus concentration2.4 × 10⸠pfu | In-vitro result97.2 +/- 4.7% cell viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID25890191 |
IDOV_2981 | Virus nameReovirus | Virus strainwild type | Virus genome typeRNA | Virus familyReoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and squamous carcinoma cell line | Cell lineUM-SCC-104 | Concentration of cell line7.68E+3 cells per well | In-vitro toxicityNA | AssayAlamar blue assay | In-vitro virus concentration2.4 × 10⸠pfu | In-vitro result82.3 +/- 6.5% cell viable after 96 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID25890191 |
IDOV_4483 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result70% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4484 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result60% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4485 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 MOI | In-vitro result50% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4486 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 MOI | In-vitro result50% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4487 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 MOI | In-vitro result40% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4488 | Virus nameHerpes simplex virus | Virus strainRH2 | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationMutant for Gamma 34.5 gene and gB gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineMurine squamous cell carcinoma | Cell lineSCCVII | Concentration of cell lineNA | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 MOI | In-vitro result30% cell survival after 12 hours | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedVirus induced apoptosis | Immunogenic effectIncreased extracellular ATP and HMGB1, indicating immunogenic cell death | Clinical trialNA | PMID26987291 |
IDOV_4619 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 VP per cell | In-vitro result100% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4620 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 VP per cell | In-vitro result100% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4621 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 VP per cell | In-vitro result100% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4622 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 VP per cell | In-vitro result100% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4623 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 VP per cell | In-vitro result100% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4624 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 VP per cell | In-vitro result40% cell viablity after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4625 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 VP per cell | In-vitro result80% cell viablity after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4626 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 VP per cell | In-vitro result80% cell viablity after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4627 | Virus nameAdenovirus | Virus strainAd5/3-CB016 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 VP per cell | In-vitro result70% cell viablity after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4628 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration1 VP per cell | In-vitro result100% cell killing after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4629 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration10 VP per cell | In-vitro result100% cell killing after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4630 | Virus nameAdenovirus | Virus strainAd5/3-delata 24 | Virus genome typeDNA | Virus familyAdenoviridae | Virus genome modificationMutation in delta E3 and delta 24 gene | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineUniversity of pitsburgh | Origin of cell lineHuman neck and squamous cell carcinoma cell line | Cell lineUPCI SCC 090 | Concentration of cell line3000 cells per well | In-vitro toxicityNA | AssayMTT assay | In-vitro virus concentration100 VP per cell | In-vitro result100% cell killing after 7 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectNA | Clinical trialNA | PMID27086483 |
IDOV_4663 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.001 MOI | In-vitro result82% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4664 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.005 MOI | In-vitro result60% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4665 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.01 MOI | In-vitro result55% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4666 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.05 MOI | In-vitro result40% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4667 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.1 MOI | In-vitro result38% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4668 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.5 MOI | In-vitro result38% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4669 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-47 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration1 MOI | In-vitro result30% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4670 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.001 MOI | In-vitro result100% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4671 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.005 MOI | In-vitro result95% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4672 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.01 MOI | In-vitro result90% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4673 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.05 MOI | In-vitro result40% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4674 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.1 MOI | In-vitro result25% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4675 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.5 MOI | In-vitro result22% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4676 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUD-SCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration1 MOI | In-vitro result20% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4677 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.001 MOI | In-vitro result90% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4678 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.005 MOI | In-vitro result70% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4679 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.01 MOI | In-vitro result65% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4680 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.05 MOI | In-vitro result50% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4681 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.1 MOI | In-vitro result40% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4682 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.5 MOI | In-vitro result38% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4683 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration1 MOI | In-vitro result38% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4684 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.001 MOI | In-vitro result90% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4685 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.005 MOI | In-vitro result82% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4686 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.01 MOI | In-vitro result60% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4687 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.05 MOI | In-vitro result60% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4688 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.1 MOI | In-vitro result50% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4689 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.5 MOI | In-vitro result40% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4690 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration1 MOI | In-vitro result38% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4691 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.001 MOI | In-vitro result90% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4692 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.005 MOI | In-vitro result82% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4693 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.01 MOI | In-vitro result76% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4694 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.05 MOI | In-vitro result62% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4695 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.1 MOI | In-vitro result62% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4696 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration0.5 MOI | In-vitro result50% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4697 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineUM-SCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayStatistical analysis | In-vitro virus concentration1 MOI | In-vitro result40% cell viability after 2 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4699 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneNo | Virus in combination with drug/radiationVirus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineSCC-74A | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro result38% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4701 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneNo | Virus in combination with drug/radiationVirus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineSCC-1 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro result40% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4702 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneNo | Virus in combination with drug/radiationVirus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineSCC-2 | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro result45% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_4703 | Virus nameHerpes simplex virus | Virus strainRAMBO | Virus genome typeDNA | Virus familyHerpesviridae | Virus genome modificationAntiangiogenic Vstat120 expressing virus | Virus aloneNo | Virus in combination with drug/radiationVirus combination with ATN-224 (8 micromolar/litre) an copper chelator show synergy | Immune gene insertion in viral genomeNo | Source of cell lineNA | Origin of cell lineHuman squamous cell carcinoma cell line | Cell lineSCC-11A | Concentration of cell lineNA | In-vitro toxicityNA | AssayCrystal violet staining | In-vitro virus concentration0.5 MOI | In-vitro result38% cell viability | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectInduce antitumor immune response | Clinical trialNA | PMID27119105 |
IDOV_5906 | Virus nameNewcastle disease virus | Virus strainNDV-B1 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and head carcinoma cell line | Cell lineSCC | Concentration of cell line5E+5 pfu | In-vitro toxicityNA | AssayLDH release assay | In-vitro virus concentration0.1 MOI | In-vitro result60% cell killing after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus induced IFN-gamma production | Clinical trialNA | PMIDUS10035984 |
IDOV_5907 | Virus nameNewcastle disease virus | Virus strainNDV-B1 | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationNone | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and head carcinoma cell line | Cell lineSCC | Concentration of cell line5E+5 pfu | In-vitro toxicityNA | AssayLDH release assay | In-vitro virus concentration0.1 MOI | In-vitro resultNo cell death observed after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus induced IFN-gamma production | Clinical trialNA | PMIDUS10035984 |
IDOV_5908 | Virus nameNewcastle disease virus | Virus strainNDV-F3aa | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationVirus expressing NS1 protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and head carcinoma cell line | Cell lineSCC | Concentration of cell line5E+5 pfu | In-vitro toxicityNA | AssayLDH release assay | In-vitro virus concentration0.1 MOI | In-vitro result100% cell killing observed after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus induced IFN-gamma production | Clinical trialNA | PMIDUS10035984 |
IDOV_5909 | Virus nameNewcastle disease virus | Virus strainNDV-F3aa | Virus genome typeRNA | Virus familyParamyxoviridae | Virus genome modificationVirus expressing NS1 protein | Virus aloneYes | Virus in combination with drug/radiationNo | Immune gene insertion in viral genomeNo | Source of cell lineATCC | Origin of cell lineHuman neck and head carcinoma cell line | Cell lineSCC | Concentration of cell line5E+5 pfu | In-vitro toxicityNA | AssayLDH release assay | In-vitro virus concentration0.1 MOI | In-vitro result70% cell killing after 3 days | Model organismNo | In-vivo virus concentrationNo | In-vivo toxicityNA | In-vivo resultNo response | Mode of deliveryNA | Pathway inducedNA | Immunogenic effectVirus induced IFN-gamma production | Clinical trialNA | PMIDUS10035984 |