Detailed description page of Selected OV_ID


OV_4630 details
Primary information
OV_IDOV_4630
Virus Name Adenovirus
StrainAd5/3-delata 24
Virus typeDNA
Virus familyAdenoviridae
Modification in virus genomeMutation in delta E3 and delta 24 gene
Virus aloneYes
Virus in combination iwth drug/radiationNo
Immune gene induction in virus genomeNo
Source of cell lineUniversity of pitsburgh
Origin of cell lineHuman neck and squamous cell carcinoma cell line
Cell lineUPCI SCC 090
Concentration of cell line3000
In-vitro toxicityNA
AssayMTT assay
In-vitro virus concentration100 VP per cell
In-vitro result100% cell killing after 7 days
Model organismNo
In-vivo virus concentrationNo
In-vivo toxicityNA
In-vivo resultNo response
Mode of deliveryNA
Pathway inductionNA
Immunogenic effectNA
Clinical trialNA
PMID27086483