Browse By Cancer Type Result Page of OvirusTdb

The total number of records retrieved from this search are 100. Click on ID to see further detail.
IDVirus nameVirus strainVirus genome typeVirus familyVirus genome modificationVirus aloneVirus in combination with drug/radiationImmune gene insertion in viral genomeSource of cell lineOrigin of cell lineCell lineConcentration of cell lineIn-vitro toxicityAssayIn-vitro virus concentrationIn-vitro resultModel organismIn-vivo virus concentrationIn-vivo toxicityIn-vivo resultMode of deliveryPathway inducedImmunogenic effectClinical trialPMID
OV_1AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay50 MOI59% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_2AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay100 MOI56% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_3AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay200 MOI49% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_4AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay50 MOI90% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_5AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay100 MOI78% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_6AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay200 MOI78% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_7AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay50 MOI70% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_8AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay100 MOI60% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_9AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell linePANC-1Grown to 70% confluenceNAMTT assay200 MOI38% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_10AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay10 MOI70% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_11AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay50 MOI58% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_12AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay100 MOI38% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_13AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay10 MOI100% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_14AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay50 MOI95% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_15AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay100 MOI94% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_16AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay10 MOI77% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_17AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay50 MOI72% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_18AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineMIAPaCa-2Grown to 70% confluenceNAMTT assay100 MOI58% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_28AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay5 MOI80% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_29AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay10 MOI78% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_30AdenovirusoAd/DCN/LRPDNAAdenoviridaeInsertional mutant for DCN and LRP geneYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay20 MOI40% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysIL-6 production increased by 3 folds as compared to normalNA26471393
OV_31AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay5 MOI90% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_32AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay10 MOI82% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_33AdenovirusoAd/DCN/LRP-PEGDNAAdenoviridaeInsertional mutant for DCN and LRP gene with polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay20 MOI84% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_34AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay5 MOI89% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_35AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay10 MOI94% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_36AdenovirusoAd/DCN/LRP-PEG-NTDNAAdenoviridaeInsertional mutant for DCN and LRP gene with NT-conjugated polyethylene glycolYesNoNoATCCHuman pancreatic cancer cell lineAsPC-1Grown to 70% confluenceNAMTT assay20 MOI94% cancer cell viabilityNoNoNA No responseNAInhibits Wnt/β-catenin and TGF-β1 signaling pathwaysNANA26471393
OV_582AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with H89(10 μM) for 1 hourNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellVery small toxicity towards human immortalized liver cell line L-02MTT assay0.001 PFU/cell86% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAJNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activatedM1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_583AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNon toxic to human immortalized liver cell line L-02MTT assay0.001 PFU/cell100% cancer cell viability at 72 hours post-infectionNoNoNA No responseNANAM1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_584AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with H89(10 μM) for 1 hourNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellVery small toxicity towards human immortalized liver cell line L-02MTT assay0.01 PFU/cell80% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAJNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activatedM1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_585AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNon toxic to human immortalized liver cell line L-02MTT assay0.01 PFU/cell100% cancer cell viability at 72 hours post-infectionNoNoNA No responseNANAM1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_586AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with H89(10 μM) for 1 hourNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellVery small toxicity towards human immortalized liver cell line L-02MTT assay0.1 PFU/cell70% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAJNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activatedM1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_587AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNon toxic to human immortalized liver cell line L-02MTT assay0.1 PFU/cell100% cancer cell viability at 72 hours post-infectionNoNoNA No responseNANAM1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_588AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with H89(10 μM) for 1 hourNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellVery small toxicity towards human immortalized liver cell line L-02MTT assay1 PFU/cell38% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAJNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activatedM1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_589AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNon toxic to human immortalized liver cell line L-02MTT assay1 PFU/cell90% cancer cell viability at 72 hours post-infectionNoNoNA No responseNANAM1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_590AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with H89(10 μM) for 1 hourNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellVery small toxicity towards human immortalized liver cell line L-02MTT assay10 PFU/cell25% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAJNK, mitochondrial apoptotic pathway, Caspase-3/7, Caspase-9 and Caspase-8 (active caspases activates downstream apoptotic pathway) are activatedM1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_591AlphavirusM1RNATogaviridaeNoneYesNoNoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNon toxic to human immortalized liver cell line L-02MTT assay10 PFU/cell80% cancer cell viability at 72 hours post-infectionNoNoNA No responseNANAM1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_600AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with ESI-09 and with H89(10 μM)NoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNAMTT assay0.1 PFU/cell75% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.M1 upregulated transcriptional ISGs (329 shown here) were inhibited by H89NA27374176
OV_601AlphavirusM1RNATogaviridaeNoneNoViral strain in combination with ESI-09NoATCCHuman pancreatic ductal adenocarcinoma cell lineCapan-14000 cells per wellNAMTT assay0.1 PFU/cell82% cancer cell viability at 72 hours post-infectionNoNoNA No responseNAESI-09 abrogates the activities of Caspase-3/9/8 induced by H89/M1 combination treatment.M1 upregulated transcriptional ISGs (329 shown here)NA27374176
OV_717Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreatic cancer cell lineBxPC-3NANAImmunoassay detection0.001 MOI130% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_718Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreatic cancer cell lineMIAPaCa-2NANAImmunoassay detection0.001 MOI70% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_719Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman caucasian pancreatic adenocarcinomaCFPAC-1NANAImmunoassay detection0.001 MOI111% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_720Avian influenza A virusH7N3 NS1-77RNAOrthomyxoviridaeMutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77)YesNoNoNAHuman pancreas adenocarcinoma cell lineAsPC-1NANAImmunoassay detection0.001 MOI128% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_721Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreatic cancer cell lineBxPC-3NANAImmunoassay detection0.001 MOI148% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_722Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreatic cancer cell lineMIAPaCa-2NANAImmunoassay detection0.001 MOI90% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_723Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman caucasian pancreatic adenocarcinomaCFPAC-1NANAImmunoassay detection0.001 MOI130% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_724Avian influenza A virusH7N3RNAOrthomyxoviridaeNoneYesNoNoNAHuman pancreas adenocarcinoma cell lineAsPC-1NANAImmunoassay detection0.001 MOI165% cancer cell death (calculated as relative to mock-infected)NoNoNA No responseNANAUp-regulation of IFN-aplhaNA27417501
OV_1406ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with norfloxacin (12.5 microgram/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.5 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1407ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with norfloxacin (12.5 microgram/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI35% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1408ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with norfloxacin (25 microgram/ml)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-3NANAMTT assay0.5 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1409ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with norfloxacin (25 microgram/ml)NoATCCHuman pancreatic adenocarcinoma cell lineBxPC-3NANAMTT assay1 MOI30% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1410ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (6.25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1411ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (6.25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1412ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (6.25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI60% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1413ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1414ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1415ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI65% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1416ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1417ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI70% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1418ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI65% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1419ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI50% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1420ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI50% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1421ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI45% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1422ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI30% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1423ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI30% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1424ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI20% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1425ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI42% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1426ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI42% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1427ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (12.5pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI40% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1428ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI20% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1429ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI20% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1430ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (25pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1431ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1432ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1433ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (50pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1434ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay0.1 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1435ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay1 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1436ParovirusH-1PVDNAParoviridaeNoneNoVirus strain in combination with reservatol (100pg/ml)NoATCCHuman pancreatic adenocarcinoma cell linePANC-1NANAMTT assay10 MOI10% cell survivalNoNoNA No responseNAInduction of apoptosis, activation of caspase 3NANA19301953
OV_1842Herpes simplex virusNV1023DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI100% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1843Herpes simplex virusNV1024DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI100% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1844Herpes simplex virusNV1025DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1845Herpes simplex virusNV1026DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.01 MOI70% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1846Herpes simplex virusNV1027DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI90% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1847Herpes simplex virusNV1028DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI90% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1848Herpes simplex virusNV1029DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI80% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1849Herpes simplex virusNV1030DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay0.1 MOI60% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1850Herpes simplex virusNV1031DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI70% cell survival after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1851Herpes simplex virusNV1032DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI65% cell survival after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1852Herpes simplex virusNV1033DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI50% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1853Herpes simplex virusNV1034DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineHs766T2.0E+4 cells per wellNALDH release assay1 MOI20% cell survival after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1854Herpes simplex virusNV1035DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1855Herpes simplex virusNV1036DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1856Herpes simplex virusNV1037DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1857Herpes simplex virusNV1038DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.1 MOINo cell killing after day 7NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1858Herpes simplex virusNV1039DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1859Herpes simplex virusNV1040DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1860Herpes simplex virusNV1041DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOI98% cell survival after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1861Herpes simplex virusNV1042DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.2 MOINo cell killing after day 5NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1862Herpes simplex virusNV1043DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 1NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009
OV_1863Herpes simplex virusNV1044DNAHerpesviridaeInsertion of HSV-2 DNA at UL and US sequences, deletion of ICP4 and gamma 34.5 geneYesNoNoATCCHuman pancreatic cancer cell lineMIA paCa-22.0E+4 cells per wellNALDH release assay0.4 MOINo cell killing after day 3NoNoNA No responseNAInduction of apoptosis by the virusNANA20629009