| Primary information |
|---|
| OV_ID | OV_719 |
| Virus Name | Avian influenza A virus |
| Strain | H7N3 NS1-77 |
| Virus type | RNA |
| Virus family | Orthomyxoviridae |
| Modification in virus genome | Mutations were introduced within the IAV NS1 gene to create a truncated protein of 77 aa (NS1-77) |
| Virus alone | Yes |
| Virus in combination iwth drug/radiation | No |
| Immune gene induction in virus genome | No |
| Source of cell line | NA |
| Origin of cell line | Human caucasian pancreatic adenocarcinoma |
| Cell line | CFPAC-1 |
| Concentration of cell line | 0 |
| In-vitro toxicity | NA |
| Assay | Immunoassay detection |
| In-vitro virus concentration | 0.001 MOI |
| In-vitro result | 111% cancer cell death (calculated as relative to mock-infected) |
| Model organism | No |
| In-vivo virus concentration | No |
| In-vivo toxicity | NA |
| In-vivo result | No response |
| Mode of delivery | NA |
| Pathway induction | NA |
| Immunogenic effect | Up-regulation of IFN-aplha |
| Clinical trial | NA |
| PMID | 27417501 |