Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 119
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1348Formula 10RKD-NH-CH2-CH2-NH-DKR6LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1349Formula 11[RKDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1350Formula 12[RLDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1351Formula 13KSKL4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1352Formula 14SKL3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1353Formula 15SSST4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1354Formula 16LET3LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1355Formula 17LTET4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1356Formula 18PKLT4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1357Formula 19KKTE4LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1358Formula 20KHL3LNoneAmidationNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1521RTL401GGGGSLVPRGSGGGG15LNoneNoneNoneLinearProtein DerivedI-As/proteolipid proteinT-cellscytokine switch in targeted T cells to produce anti-inflammatory cytokines,reduction of infiltrating mononuclear cells into CNSIn vivoNANASJL miceImmunoblotting, Cytokine determination by cytometric bead array, ELISANAautoimmune encepha- lomyelitis 161481602005
1524119RVAALEEANTELEVKI15LNoneNoneNoneLinearProtein Derivedkeratin 17Psoriatic T-cells and keratinocyteInhibition of T-cell proliferation , secretion of interferon gamma and interleukin 2 and up-regulation of interleukins 4 and 10In vitroNANANACytokine secretion assay, T-cell proliferation assayNANA167134532006
1525355LENRYCVQASQIQGLI15LNoneNoneNoneLinearProtein Derivedkeratin 18Psoriatic T-cells and keratinocyteInhibition of T-cell proliferation , secretion of interferon gamma and interleukin 2 and up-regulation of interleukins 4 and 11In vitroNANANACytokine secretion assay, T-cell proliferation assayNANA167134532006
1526A12GEBGIAGNKGDQGPKGEBGPA21LNoneNoneNoneLinearProtein DerivedType II collagenT-cellsDecrease in IFN-γ and increase in IL-4 productionIn vivoNANADR4 transgenic MiceELISA, Class II binding assay, Proliferation assayNANA169820032006
1529p33-48DSVTPMILKAQK GGNL16LNoneNoneNoneLinearProtein DerivedDog allergen Can f 1T-CellsElevated production of IFN-c and IL-10In vitroPeptide-specific T cell linesNANALymphocyte proliferation assay, ELISA, FACSNANA172337392006
1530p107-122RQIRMAKLLGRDPEQS16LNoneNoneNoneLinearProtein DerivedDog allergen Can f 2T-CellsElevated production of IFN-c and IL-11In vitroPeptide-specific T cell linesNANALymphocyte proliferation assay, ELISA, FACSNANA172337392006
1531PLP-BPIHSLGKWLGHPDKF-AcGAcGAc-ITDGEATDSG23LNoneNoneChemical linker AcGAcGAc, where Ac is ε- aminicaproic acidLinearSyntheticProteolipid protein (PLP) and bifunctional peptide inhibitor (BPI)Regulatory T-CellIncrease in CD4+ CD25+TGF-β+ , CD4 +CD25+ IL-4+ ,and CD4+ CD25+ IL-10 + T cells also CD4+ CD25+ IFN-γ+ cells In vivoNANASJL/J (H-2s) female miceNANANA175223432007
1545H471TYTEHAKRKTVTAMDVVYALKRQ23LNoneNoneNoneLinearProtein DerivedHistone H4 proteinT-cell epitope of histone protein H4 of mononucleosomeProducing large amount of IL-10 and decreasing IFN-gamma by lymph node cellsBothLN cellsNALupus prone SNF1 female miceELISA, Cell Proliferation Assay, Ce1ELISANACFA120974222002