1348 | Formula 10 | RKD-NH-CH2-CH2-NH-DKR | 6 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1349 | Formula 11 | [RKDV-NH-CH2]2 | 8 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1350 | Formula 12 | [RLDV-NH-CH2]2 | 8 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1351 | Formula 13 | KSKL | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1352 | Formula 14 | SKL | 3 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1353 | Formula 15 | SSST | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1354 | Formula 16 | LET | 3 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1355 | Formula 17 | LTET | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1356 | Formula 18 | PKLT | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1357 | Formula 19 | KKTE | 4 | L | None | None | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1358 | Formula 20 | KHL | 3 | L | None | Amidation | None | Linear | Synthetic | NA | Suppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processes | Inhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive response | In vitro | Splenocyte s obtained from rats | NA | Twelve Wistar (LATI) rats | Hummoral Immune Response assay | NA | NA | US 5093320 | 1992 |
1521 | RTL401 | GGGGSLVPRGSGGGG | 15 | L | None | None | None | Linear | Protein Derived | I-As/proteolipid protein | T-cells | cytokine switch in targeted T cells to produce anti-inflammatory cytokines,reduction of infiltrating mononuclear cells into CNS | In vivo | NA | NA | SJL mice | Immunoblotting, Cytokine determination by cytometric bead array, ELISA | NA | autoimmune encepha- lomyelitis | 16148160 | 2005 |
1524 | 119R | VAALEEANTELEVKI | 15 | L | None | None | None | Linear | Protein Derived | keratin 17 | Psoriatic T-cells and keratinocyte | Inhibition of T-cell proliferation , secretion of interferon gamma and interleukin 2 and up-regulation of interleukins 4 and 10 | In vitro | NA | NA | NA | Cytokine secretion assay, T-cell proliferation assay | NA | NA | 16713453 | 2006 |
1525 | 355L | ENRYCVQASQIQGLI | 15 | L | None | None | None | Linear | Protein Derived | keratin 18 | Psoriatic T-cells and keratinocyte | Inhibition of T-cell proliferation , secretion of interferon gamma and interleukin 2 and up-regulation of interleukins 4 and 11 | In vitro | NA | NA | NA | Cytokine secretion assay, T-cell proliferation assay | NA | NA | 16713453 | 2006 |
1526 | A12 | GEBGIAGNKGDQGPKGEBGPA | 21 | L | None | None | None | Linear | Protein Derived | Type II collagen | T-cells | Decrease in IFN-γ and increase in IL-4 production | In vivo | NA | NA | DR4 transgenic Mice | ELISA, Class II binding assay, Proliferation assay | NA | NA | 16982003 | 2006 |
1529 | p33-48 | DSVTPMILKAQK GGNL | 16 | L | None | None | None | Linear | Protein Derived | Dog allergen Can f 1 | T-Cells | Elevated production of IFN-c and IL-10 | In vitro | Peptide-specific T cell lines | NA | NA | Lymphocyte proliferation assay, ELISA, FACS | NA | NA | 17233739 | 2006 |
1530 | p107-122 | RQIRMAKLLGRDPEQS | 16 | L | None | None | None | Linear | Protein Derived | Dog allergen Can f 2 | T-Cells | Elevated production of IFN-c and IL-11 | In vitro | Peptide-specific T cell lines | NA | NA | Lymphocyte proliferation assay, ELISA, FACS | NA | NA | 17233739 | 2006 |
1531 | PLP-BPI | HSLGKWLGHPDKF-AcGAcGAc-ITDGEATDSG | 23 | L | None | None | Chemical linker AcGAcGAc, where Ac is ε- aminicaproic acid | Linear | Synthetic | Proteolipid protein (PLP) and bifunctional peptide inhibitor (BPI) | Regulatory T-Cell | Increase in CD4+ CD25+TGF-β+ , CD4 +CD25+ IL-4+ ,and CD4+ CD25+ IL-10 + T cells also CD4+ CD25+ IFN-γ+ cells | In vivo | NA | NA | SJL/J (H-2s) female mice | NA | NA | NA | 17522343 | 2007 |
1545 | H471 | TYTEHAKRKTVTAMDVVYALKRQ | 23 | L | None | None | None | Linear | Protein Derived | Histone H4 protein | T-cell epitope of histone protein H4 of mononucleosome | Producing large amount of IL-10 and decreasing IFN-gamma by lymph node cells | Both | LN cells | NA | Lupus prone SNF1 female mice | ELISA, Cell Proliferation Assay, Ce1ELISA | NA | CFA | 12097422 | 2002 |