Primary information |
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ID | 1545 |
Peptide Name | H471 |
Sequence | TYTEHAKRKTVTAMDVVYALKRQ |
Length | 23 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | Histone H4 protein |
Target | T-cell epitope of histone protein H4 of mononucleosome |
Mechanism of Action | Producing large amount of IL-10 and decreasing IFN-gamma by lymph node cells |
In vitro/In vivo | Both |
Cell Line | LN cells |
Inhibition Concentartion | NA |
In vivo Model | Lupus prone SNF1 female mice |
Assay | ELISA, Cell Proliferation Assay, Ce1ELISA |
Lethal Dose | NA |
Combination Therapy | CFA |
Pubmed ID | 12097422 |
Year of Publication | 2002 |
3-D Structure | View in Jmol or Download Structure |