| Primary information |
|---|
| ID | 1545 |
| Peptide Name | H471 |
| Sequence | TYTEHAKRKTVTAMDVVYALKRQ |
| Length | 23 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | Histone H4 protein |
| Target | T-cell epitope of histone protein H4 of mononucleosome |
| Mechanism of Action | Producing large amount of IL-10 and decreasing IFN-gamma by lymph node cells |
| In vitro/In vivo | Both |
| Cell Line | LN cells |
| Inhibition Concentartion | NA |
| In vivo Model | Lupus prone SNF1 female mice |
| Assay | ELISA, Cell Proliferation Assay, Ce1ELISA |
| Lethal Dose | NA |
| Combination Therapy | CFA |
| Pubmed ID | 12097422 |
| Year of Publication | 2002 |
| 3-D Structure |  View in Jmol or Download Structure |
