| Primary information |
|---|
| ID | 1531 |
| Peptide Name | PLP-BPI |
| Sequence | HSLGKWLGHPDKF-AcGAcGAc-ITDGEATDSG |
| Length | 23 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | Chemical linker AcGAcGAc, where Ac is ε- aminicaproic acid |
| Linear/ Cyclic | Linear |
| Nature | Synthetic |
| Source of Origin | Proteolipid protein (PLP) and bifunctional peptide inhibitor (BPI) |
| Target | Regulatory T-Cell |
| Mechanism of Action | Increase in CD4+ CD25+TGF-β+ , CD4 +CD25+ IL-4+ ,and CD4+ CD25+ IL-10 + T cells also CD4+ CD25+ IFN-γ+ cells |
| In vitro/In vivo | In vivo |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| In vivo Model | SJL/J (H-2s) female mice |
| Assay | NA |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 17522343 |
| Year of Publication | 2007 |
| 3-D Structure | NA |
