| Primary information |
|---|
| ID | 1521 |
| Peptide Name | RTL401 |
| Sequence | GGGGSLVPRGSGGGG |
| Length | 15 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | I-As/proteolipid protein |
| Target | T-cells |
| Mechanism of Action | cytokine switch in targeted T cells to produce anti-inflammatory cytokines,reduction of infiltrating mononuclear cells into CNS |
| In vitro/In vivo | In vivo |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| In vivo Model | SJL mice |
| Assay | Immunoblotting, Cytokine determination by cytometric bead array, ELISA |
| Lethal Dose | NA |
| Combination Therapy | autoimmune encepha- lomyelitis |
| Pubmed ID | 16148160 |
| Year of Publication | 2005 |
| 3-D Structure |  View in Jmol or Download Structure |
