Primary information |
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ID | 1521 |
Peptide Name | RTL401 |
Sequence | GGGGSLVPRGSGGGG |
Length | 15 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | I-As/proteolipid protein |
Target | T-cells |
Mechanism of Action | cytokine switch in targeted T cells to produce anti-inflammatory cytokines,reduction of infiltrating mononuclear cells into CNS |
In vitro/In vivo | In vivo |
Cell Line | NA |
Inhibition Concentartion | NA |
In vivo Model | SJL mice |
Assay | Immunoblotting, Cytokine determination by cytometric bead array, ELISA |
Lethal Dose | NA |
Combination Therapy | autoimmune encepha- lomyelitis |
Pubmed ID | 16148160 |
Year of Publication | 2005 |
3-D Structure | View in Jmol or Download Structure |