Primary information |
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ID | 1525 |
Peptide Name | 355L |
Sequence | ENRYCVQASQIQGLI |
Length | 15 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | keratin 18 |
Target | Psoriatic T-cells and keratinocyte |
Mechanism of Action | Inhibition of T-cell proliferation , secretion of interferon gamma and interleukin 2 and up-regulation of interleukins 4 and 11 |
In vitro/In vivo | In vitro |
Cell Line | NA |
Inhibition Concentartion | NA |
In vivo Model | NA |
Assay | Cytokine secretion assay, T-cell proliferation assay |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 16713453 |
Year of Publication | 2006 |
3-D Structure | View in Jmol or Download Structure |