Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_001803                                                              17    2528
XP_006714128                                                           17    2528
XP_006714127                                                           17    2528
NP_055874                                                              17    4312
XP_006720784                                                           17    4312
XP_006720783                                                           17    4312
XP_006720782                                                           17    4312
XP_006720781                                                           17    4312
XP_005254772                                                           17    4312
XP_005254771                                                           17    4312
XP_006720780                                                           17    4312
XP_005254769                                                           17    4312
XP_005254770                                                           17    4312
XP_005254765                                                           17    4312
XP_005254767                                                           17    4312
XP_006720779                                                           17    4312
XP_005254768                                                           17    4312
XP_005254764                                                           17    4312
NP_057197                                                              16    5631
NP_001073936                                                           16    5631
NP_037524                                                              16    5631
NP_036395                                                              16    5631
XP_006724288                                                           16    5631
XP_006721606                                                           16    5631
XP_006721605                                                           16    5631
XP_006721604                                                           16    5631
XP_005256733                                                           16    5631
XP_006716564                                                           16    5631
XP_005250826                                                           16    5631
XP_005264331                                                           16    5631
NP_001106                                                              16    5631
NP_005926                                                              16    7355
NP_001160165                                                           16    7355
NP_079039                                                              16    7355
NP_996897                                                              16    7355
NP_001004699                                                           16    7355
XP_005263070                                                           16    7355
XP_005263069                                                           16    7355
XP_005263068                                                           16    7355
XP_005263067                                                           16    7355
XP_005263066                                                           16    7355
XP_005263065                                                           16    7355
XP_005263064                                                           16    7355
XP_005271269                                                           16    7355
NP_001177957                                                           15    9605
NP_036602                                                              15    9605
NP_054733                                                              15    9605
NP_000250                                                              15    9605
NP_001135967                                                           15    9605
NP_001864                                                              15    9605
XP_005254459                                                           15    9605
XP_005254458                                                           15    9605
XP_005254457                                                           15    9605
XP_005254456                                                           15    9605
XP_005254455                                                           15    9605
XP_005254454                                                           15    9605
XP_006715974                                                           15    9605
NP_001004492                                                           15    9605
NP_061735                                                              15    9605
NP_114382                                                              15    9605
NP_001005276                                                           15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YSL SETIN
Sbjct: 1560 YSLFSETIN 1568
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YSL SETIN
Sbjct: 1560 YSLFSETIN 1568
>NP_001803
          Length = 943

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           Y+L+ ET+N
Sbjct: 385 YALIGETVN 393
>XP_006714128
          Length = 730

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           Y+L+ ET+N
Sbjct: 172 YALIGETVN 180
>XP_006714127
          Length = 935

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           Y+L+ ET+N
Sbjct: 385 YALIGETVN 393
>NP_055874
          Length = 2542

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720784
          Length = 2502

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720783
          Length = 2512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720782
          Length = 2517

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720781
          Length = 2542

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254772
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254771
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720780
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254769
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254770
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254765
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254767
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_006720779
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254768
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>XP_005254764
          Length = 2557

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ ETI
Sbjct: 129 YSLIQETI 136
>NP_057197
          Length = 764

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLLSETIN 9
           +L+SET+N
Sbjct: 643 ALMSETVN 650
>NP_001073936
          Length = 1848

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            +SLL+ TIN
Sbjct: 1522 HSLLTSTIN 1530
>NP_037524
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLLSETIN 9
           SLL ET+N
Sbjct: 509 SLLEETLN 516
>NP_036395
          Length = 423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   YSLLSETIN 9
           Y+L+++T+N
Sbjct: 345 YNLINDTLN 353
>XP_006724288
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   YSLLSETIN 9
           Y+L+++T+N
Sbjct: 248 YNLINDTLN 256
>XP_006721606
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLLSETIN 9
           +L+SET+N
Sbjct: 643 ALMSETVN 650
>XP_006721605
          Length = 680

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLLSETIN 9
           +L+SET+N
Sbjct: 643 ALMSETVN 650
>XP_006721604
          Length = 733

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLLSETIN 9
           +L+SET+N
Sbjct: 643 ALMSETVN 650
>XP_005256733
          Length = 763

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SLLSETIN 9
           +L+SET+N
Sbjct: 642 ALMSETVN 649
>XP_006716564
          Length = 1185

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YSLLSETI 8
           Y+LL+ET+
Sbjct: 803 YALLTETV 810
>XP_005250826
          Length = 1221

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YSLLSETI 8
           Y+LL+ET+
Sbjct: 839 YALLTETV 846
>XP_005264331
          Length = 535

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLLSETIN 9
           SLL ET+N
Sbjct: 509 SLLEETLN 516
>NP_001106
          Length = 1251

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YSLLSETI 8
           Y+LL+ET+
Sbjct: 869 YALLTETV 876
>NP_005926
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1016 YSVYSETVD 1024
>NP_001160165
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1023 YSVYSETVD 1031
>NP_079039
          Length = 848

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YSLLSETIN 9
           YSL   TIN
Sbjct: 160 YSLYQNTIN 168
>NP_996897
          Length = 545

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YSLLSETIN 9
           YSL   TIN
Sbjct: 160 YSLYQNTIN 168
>NP_001004699
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           YSL++ T+N
Sbjct: 278 YSLVTPTLN 286
>XP_005263070
          Length = 1057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1023 YSVYSETVD 1031
>XP_005263069
          Length = 1211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1016 YSVYSETVD 1024
>XP_005263068
          Length = 1216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1021 YSVYSETVD 1029
>XP_005263067
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1023 YSVYSETVD 1031
>XP_005263066
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1022 YSVYSETVD 1030
>XP_005263065
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1023 YSVYSETVD 1031
>XP_005263064
          Length = 1218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YSLLSETIN 9
            YS+ SET++
Sbjct: 1023 YSVYSETVD 1031
>XP_005271269
          Length = 783

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YSLLSETIN 9
           YSL   TIN
Sbjct: 160 YSLYQNTIN 168
>NP_001177957
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           + +LSET+N
Sbjct: 578 WPVLSETLN 586
>NP_036602
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           + +LSET+N
Sbjct: 642 WPVLSETLN 650
>NP_054733
          Length = 2136

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  YSLLSETIN 9
          Y+LLSE I+
Sbjct: 87 YTLLSEGID 95
>NP_000250
          Length = 1855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1531 SLLTSTIN 1538
>NP_001135967
          Length = 1828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1504 SLLTSTIN 1511
>NP_001864
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           + ++SET+N
Sbjct: 467 WKMMSETLN 475
>XP_005254459
          Length = 1825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1501 SLLTSTIN 1508
>XP_005254458
          Length = 1852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1528 SLLTSTIN 1535
>XP_005254457
          Length = 1853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1529 SLLTSTIN 1536
>XP_005254456
          Length = 1877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1553 SLLTSTIN 1560
>XP_005254455
          Length = 1880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1556 SLLTSTIN 1563
>XP_005254454
          Length = 1880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    SLLSETIN 9
            SLL+ TIN
Sbjct: 1556 SLLTSTIN 1563
>XP_006715974
          Length = 875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           + +LSET+N
Sbjct: 594 WPVLSETLN 602
>NP_001004492
          Length = 317

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           YS+++ T+N
Sbjct: 282 YSIITPTLN 290
>NP_061735
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ +TI
Sbjct: 489 YSLIEDTI 496
>NP_114382
          Length = 823

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YSLLSETI 8
           YSL+ +TI
Sbjct: 489 YSLIEDTI 496
>NP_001005276
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YSLLSETIN 9
           YS+++ T+N
Sbjct: 277 YSIITPTLN 285
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.124    0.303 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 349,186
Number of extensions: 559
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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