Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055726                                                              19     869
NP_055845                                                              17    2528
XP_005248150                                                           17    2528
XP_005248148                                                           17    2528
XP_005248147                                                           17    2528
XP_005248146                                                           17    2528
XP_005248145                                                           17    2528
XP_005248144                                                           17    2528
XP_005248143                                                           17    2528
XP_005248142                                                           17    2528
XP_005248141                                                           17    2528
XP_005248140                                                           17    2528
XP_005248139                                                           17    2528
NP_001245308                                                           17    3301
NP_003606                                                              17    3301
NP_001245309                                                           17    3301
XP_005265658                                                           17    3301
XP_005265657                                                           17    3301
XP_005265656                                                           17    3301
XP_005265655                                                           17    3301
XP_006713484                                                           17    3301
NP_006013                                                              16    5631
NP_001265546                                                           16    5631
NP_001265545                                                           16    5631
NP_004327                                                              16    5631
NP_060063                                                              16    5631
NP_942595                                                              16    5631
XP_005263174                                                           16    5631
NP_002435                                                              16    7355
NP_078858                                                              16    7355
NP_001278232                                                           16    7355
NP_001278214                                                           16    7355
NP_079199                                                              16    7355
NP_078904                                                              16    7355
NP_001182412                                                           16    7355
XP_005262326                                                           16    7355
XP_005268801                                                           16    7355
XP_005268800                                                           16    7355
XP_005268799                                                           16    7355
XP_005250261                                                           16    7355
NP_690852                                                              16    7355
NP_056090                                                              16    7355
NP_061893                                                              15    9605
NP_008970                                                              15    9605
NP_001258773                                                           15    9605
NP_001258774                                                           15    9605
XP_005257107                                                           15    9605
XP_006721757                                                           15    9605
XP_005257106                                                           15    9605
XP_005267344                                                           15    9605
>NP_055726
          Length = 961

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   YQVSYFS 7
           YQVSYFS
Sbjct: 305 YQVSYFS 311
>NP_055845
          Length = 3013

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1264 YSVSYYQLS 1272
>XP_005248150
          Length = 2044

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YQVSYFSLS 9
           Y VSY+ LS
Sbjct: 295 YSVSYYQLS 303
>XP_005248148
          Length = 3028

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1279 YSVSYYQLS 1287
>XP_005248147
          Length = 3028

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1279 YSVSYYQLS 1287
>XP_005248146
          Length = 3073

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1371 YSVSYYQLS 1379
>XP_005248145
          Length = 3079

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1330 YSVSYYQLS 1338
>XP_005248144
          Length = 3099

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1356 YSVSYYQLS 1364
>XP_005248143
          Length = 3105

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1356 YSVSYYQLS 1364
>XP_005248142
          Length = 3114

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1371 YSVSYYQLS 1379
>XP_005248141
          Length = 3119

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1371 YSVSYYQLS 1379
>XP_005248140
          Length = 3119

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1370 YSVSYYQLS 1378
>XP_005248139
          Length = 3120

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YQVSYFSLS 9
            Y VSY+ LS
Sbjct: 1371 YSVSYYQLS 1379
>NP_001245308
          Length = 1131

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 566 YQLSYLSL 573
>NP_003606
          Length = 1214

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 685 YQLSYLSL 692
>NP_001245309
          Length = 1090

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 561 YQLSYLSL 568
>XP_005265658
          Length = 1095

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 566 YQLSYLSL 573
>XP_005265657
          Length = 1113

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 548 YQLSYLSL 555
>XP_005265656
          Length = 1118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 553 YQLSYLSL 560
>XP_005265655
          Length = 1126

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 561 YQLSYLSL 568
>XP_006713484
          Length = 1255

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           YQ+SY SL
Sbjct: 690 YQLSYLSL 697
>NP_006013
          Length = 144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  YQVSYFSLS 9
          YQ+ +FS+S
Sbjct: 16 YQLRHFSIS 24
>NP_001265546
          Length = 1028

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   YQVSYFSLS 9
           YQ+ YF ++
Sbjct: 927 YQIDYFGVA 935
>NP_001265545
          Length = 1065

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   YQVSYFSLS 9
           YQ+ YF ++
Sbjct: 964 YQIDYFGVA 972
>NP_004327
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   YQVSYFSLS 9
           YQ+ YF ++
Sbjct: 984 YQIDYFGVA 992
>NP_060063
          Length = 662

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YQVSYFS 7
           +QVSYF+
Sbjct: 309 FQVSYFA 315
>NP_942595
          Length = 1161

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YQVSYFS 7
           +QVSYF+
Sbjct: 309 FQVSYFA 315
>XP_005263174
          Length = 1124

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YQVSYFS 7
           +QVSYF+
Sbjct: 309 FQVSYFA 315
>NP_002435
          Length = 577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           Y V+YFS+
Sbjct: 201 YGVNYFSI 208
>NP_078858
          Length = 4981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SYFSLS 9
            SYFSLS
Sbjct: 3556 SYFSLS 3561
>NP_001278232
          Length = 4983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SYFSLS 9
            SYFSLS
Sbjct: 3558 SYFSLS 3563
>NP_001278214
          Length = 4982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4    SYFSLS 9
            SYFSLS
Sbjct: 3558 SYFSLS 3563
>NP_079199
          Length = 1887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YQVSYFSL 8
            YQV +F+L
Sbjct: 1807 YQVMFFTL 1814
>NP_078904
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYFSLS 9
           SYFSLS
Sbjct: 401 SYFSLS 406
>NP_001182412
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYFSLS 9
           SYFSLS
Sbjct: 401 SYFSLS 406
>XP_005262326
          Length = 578

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YQVSYFSL 8
           Y V+YFS+
Sbjct: 202 YGVNYFSI 209
>XP_005268801
          Length = 985

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YQVSYFSLS 9
           +++ YFSLS
Sbjct: 932 FELLYFSLS 940
>XP_005268800
          Length = 986

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YQVSYFSLS 9
           +++ YFSLS
Sbjct: 933 FELLYFSLS 941
>XP_005268799
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YQVSYFSLS 9
            +++ YFSLS
Sbjct: 1121 FELLYFSLS 1129
>XP_005250261
          Length = 495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSYFSLS 9
           +++YFSLS
Sbjct: 401 ELAYFSLS 408
>NP_690852
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSYFSLS 9
           +++YFSLS
Sbjct: 553 ELAYFSLS 560
>NP_056090
          Length = 1173

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YQVSYFSLS 9
            +++ YFSLS
Sbjct: 1120 FELLYFSLS 1128
>NP_061893
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 635 YQTDYFHL 642
>NP_008970
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QVSYFSL 8
          +V+YFSL
Sbjct: 60 EVTYFSL 66
>NP_001258773
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 260 YQTDYFHL 267
>NP_001258774
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 273 YQTDYFHL 280
>XP_005257107
          Length = 766

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 634 YQTDYFHL 641
>XP_006721757
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 635 YQTDYFHL 642
>XP_005257106
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YQVSYFSL 8
           YQ  YF L
Sbjct: 635 YQTDYFHL 642
>XP_005267344
          Length = 1174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QVSYFSL 8
          +V+YFSL
Sbjct: 60 EVTYFSL 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.129    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,033
Number of extensions: 530
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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