Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000334                                                              19     869
NP_001243243                                                           19     869
NP_002430                                                              19     869
NP_003032                                                              18    1135
XP_006721136                                                           18    1135
XP_006721135                                                           18    1135
NP_001398                                                              17    2528
NP_001032                                                              17    3301
NP_002564                                                              17    3301
NP_001139412                                                           17    3301
NP_001139411                                                           17    3301
NP_002554                                                              17    4312
NP_055061                                                              17    4312
XP_006724446                                                           17    4312
NP_859070                                                              16    5631
XP_005245884                                                           16    5631
XP_005245882                                                           16    5631
XP_006710614                                                           16    5631
XP_005245881                                                           16    5631
XP_005245880                                                           16    5631
XP_006710613                                                           16    5631
XP_005245879                                                           16    5631
NP_001001991                                                           16    7355
NP_001269605                                                           16    7355
NP_056245                                                              16    7355
NP_001269604                                                           16    7355
NP_001036065                                                           16    7355
NP_009112                                                              16    7355
XP_006723056                                                           16    7355
NP_957719                                                              15    9605
NP_061004                                                              15    9605
NP_003863                                                              15    9605
NP_958436                                                              15    9605
NP_957718                                                              15    9605
NP_079095                                                              15    9605
NP_001275584                                                           15    9605
NP_001275583                                                           15    9605
NP_001122103                                                           15    9605
NP_689997                                                              15    9605
NP_001008781                                                           15    9605
NP_060009                                                              15    9605
NP_078928                                                              15    9605
NP_002842                                                              15    9605
NP_001193767                                                           15    9605
XP_005257745                                                           15    9605
XP_006722156                                                           15    9605
XP_006722155                                                           15    9605
XP_006722154                                                           15    9605
XP_006721125                                                           15    9605
XP_005255036                                                           15    9605
XP_006718827                                                           15    9605
XP_006716139                                                           15    9605
XP_005250576                                                           15    9605
XP_005246991                                                           15    9605
XP_005246990                                                           15    9605
NP_001193768                                                           15    9605
NP_149059                                                              15    9605
>NP_000334
          Length = 664

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   YQITGGIAA 9
           Y ITGG+AA
Sbjct: 191 YTITGGLAA 199
>NP_001243243
          Length = 537

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  YQITGGIAA 9
          Y ITGG+AA
Sbjct: 64 YTITGGLAA 72
>NP_002430
          Length = 1137

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YQITGGIAA 9
            YQIT GIAA
Sbjct: 1057 YQITRGIAA 1065
>NP_003032
          Length = 672

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YQITGGIAA 9
           Y +TGG+AA
Sbjct: 188 YTVTGGLAA 196
>XP_006721136
          Length = 425

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YQITGGIAA 9
           Y +TGG+AA
Sbjct: 176 YTVTGGLAA 184
>XP_006721135
          Length = 698

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YQITGGIAA 9
           Y +TGG+AA
Sbjct: 188 YTVTGGLAA 196
>NP_001398
          Length = 3312

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YQITGG 6
           YQITGG
Sbjct: 791 YQITGG 796
>NP_001032
          Length = 1827

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YQITGGI 7
           Y++TGGI
Sbjct: 314 YRVTGGI 320
>NP_002564
          Length = 231

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QITGGIAA 9
           Q+TGGI A
Sbjct: 112 QVTGGIKA 119
>NP_001139412
          Length = 231

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QITGGIAA 9
           Q+TGGI A
Sbjct: 112 QVTGGIKA 119
>NP_001139411
          Length = 231

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QITGGIAA 9
           Q+TGGI A
Sbjct: 112 QVTGGIKA 119
>NP_002554
          Length = 373

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YQITGGIAA 9
           YQ+T G+A+
Sbjct: 306 YQVTRGLAS 314
>NP_055061
          Length = 3014

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YQITGG 6
           YQ+TGG
Sbjct: 722 YQLTGG 727
>XP_006724446
          Length = 3019

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YQITGG 6
           YQ+TGG
Sbjct: 722 YQLTGG 727
>NP_859070
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245884
          Length = 594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245882
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_006710614
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245881
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245880
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_006710613
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>XP_005245879
          Length = 634

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ITGGIAA 9
           +TGG+AA
Sbjct: 206 VTGGLAA 212
>NP_001001991
          Length = 720

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TGGIAA 9
           TGGIAA
Sbjct: 665 TGGIAA 670
>NP_001269605
          Length = 609

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TGGIAA 9
           TGGIAA
Sbjct: 554 TGGIAA 559
>NP_056245
          Length = 737

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TGGIAA 9
           TGGIAA
Sbjct: 682 TGGIAA 687
>NP_001269604
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TGGIAA 9
           TGGIAA
Sbjct: 625 TGGIAA 630
>NP_001036065
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YQITGGIA 8
           YQ+TG ++
Sbjct: 103 YQVTGSLS 110
>NP_009112
          Length = 833

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YQITGGIA 8
           YQ+TG ++
Sbjct: 103 YQVTGSLS 110
>XP_006723056
          Length = 801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YQITGGIA 8
           YQ+TG ++
Sbjct: 103 YQVTGSLS 110
>NP_957719
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_061004
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_003863
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_958436
          Length = 909

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_957718
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_079095
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001275584
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001275583
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_001122103
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>NP_689997
          Length = 798

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YQITGGIAA 9
           YQI GG  A
Sbjct: 668 YQILGGRTA 676
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    YQITGG 6
            Y ITGG
Sbjct: 2962 YHITGG 2967
>NP_060009
          Length = 4116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YQITGGIA 8
            + +TGGIA
Sbjct: 3395 FLLTGGIA 3402
>NP_078928
          Length = 2015

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    YQITGGIA 8
            YQI  G+A
Sbjct: 1368 YQIASGLA 1375
>NP_002842
          Length = 2315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   YQITGGIA 8
           Y+++GG++
Sbjct: 110 YRVSGGVS 117
>NP_001193767
          Length = 1455

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   YQITGGIA 8
           Y+++GG++
Sbjct: 110 YRVSGGVS 117
>XP_005257745
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722156
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722155
          Length = 132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006722154
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  ITGGIAA 9
          +TGGIA+
Sbjct: 6  LTGGIAS 12
>XP_006721125
          Length = 4070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YQITGGIA 8
            + +TGGIA
Sbjct: 3349 FLLTGGIA 3356
>XP_005255036
          Length = 1310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YQITGGIA 8
           YQI  G+A
Sbjct: 663 YQIASGLA 670
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    YQITGG 6
            Y ITGG
Sbjct: 1852 YHITGG 1857
>XP_006716139
          Length = 1869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   YQITGGIA 8
           Y+++GG++
Sbjct: 110 YRVSGGVS 117
>XP_005250576
          Length = 2308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   YQITGGIA 8
           Y+++GG++
Sbjct: 110 YRVSGGVS 117
>XP_005246991
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>XP_005246990
          Length = 931

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YQITGG 6
           YQ TGG
Sbjct: 720 YQATGG 725
>NP_001193768
          Length = 1448

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 1   YQITGGIA 8
           Y+++GG++
Sbjct: 110 YRVSGGVS 117
>NP_149059
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   QITGGI 7
           Q+TGGI
Sbjct: 256 QLTGGI 261
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.139    0.396 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 569,495
Number of extensions: 824
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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