Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001013433                                                           19     665
NP_060785                                                              19     665
NP_361014                                                              19     665
NP_116195                                                              18    1935
XP_006713424                                                           18    1935
XP_005265572                                                           18    1935
NP_061182                                                              17    2528
NP_001123509                                                           17    2528
NP_005036                                                              17    4312
NP_774959                                                              17    4312
NP_006284                                                              17    4312
NP_789787                                                              17    4312
NP_775882                                                              16    7355
NP_001139661                                                           16    7355
NP_001139662                                                           16    7355
NP_683692                                                              16    7355
NP_001120650                                                           16    7355
NP_001275980                                                           16    7355
NP_002550                                                              16    7355
NP_060203                                                              16    7355
NP_060227                                                              16    7355
NP_001275982                                                           16    7355
NP_001275981                                                           16    7355
XP_006722564                                                           16    7355
XP_006722563                                                           16    7355
XP_005266783                                                           16    7355
XP_006714215                                                           16    7355
XP_006714214                                                           16    7355
XP_005262915                                                           16    7355
XP_005248208                                                           16    7355
XP_005248207                                                           16    7355
XP_006714021                                                           16    7355
XP_005272346                                                           16    7355
XP_005272345                                                           16    7355
XP_005272344                                                           16    7355
XP_006713955                                                           16    7355
XP_005272341                                                           16    7355
XP_005272340                                                           16    7355
NP_055806                                                              16    7355
NP_001001952                                                           16    7355
NP_001243092                                                           15    9605
NP_001243095                                                           15    9605
NP_001157                                                              15    9605
NP_006609                                                              15    9605
NP_976328                                                              15    9605
NP_006222                                                              15    9605
NP_060919                                                              15    9605
NP_005305                                                              15    9605
NP_001138871                                                           15    9605
NP_036296                                                              15    9605
NP_001037835                                                           15    9605
NP_001575                                                              15    9605
XP_006726852                                                           15    9605
XP_006723594                                                           15    9605
XP_006718368                                                           15    9605
XP_005253171                                                           15    9605
XP_005253170                                                           15    9605
XP_006718367                                                           15    9605
XP_005253169                                                           15    9605
XP_005253168                                                           15    9605
XP_005253167                                                           15    9605
XP_005251970                                                           15    9605
XP_005251969                                                           15    9605
XP_006717114                                                           15    9605
XP_005251967                                                           15    9605
XP_006717113                                                           15    9605
XP_006717112                                                           15    9605
XP_005251965                                                           15    9605
XP_006710109                                                           15    9605
NP_001004474                                                           15    9605
>NP_001013433
          Length = 589

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           NILVSGNA
Sbjct: 474 NILVSGNA 481
>NP_060785
          Length = 627

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           NILVSGNA
Sbjct: 512 NILVSGNA 519
>NP_361014
          Length = 707

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           NILVSGNA
Sbjct: 592 NILVSGNA 599
>NP_116195
          Length = 580

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   NILVSGN 8
           NILVSGN
Sbjct: 256 NILVSGN 262
>XP_006713424
          Length = 580

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   NILVSGN 8
           NILVSGN
Sbjct: 256 NILVSGN 262
>XP_005265572
          Length = 580

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   NILVSGN 8
           NILVSGN
Sbjct: 256 NILVSGN 262
>NP_061182
          Length = 334

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YNILVSG 7
           YN+LVSG
Sbjct: 248 YNLLVSG 254
>NP_001123509
          Length = 326

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YNILVSG 7
           YN+LVSG
Sbjct: 240 YNLLVSG 246
>NP_005036
          Length = 3460

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NILVSGNA 9
            N+L+SG+A
Sbjct: 2657 NVLISGSA 2664
>NP_774959
          Length = 3458

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    NILVSGNA 9
            N+L+SG+A
Sbjct: 2657 NVLISGSA 2664
>NP_006284
          Length = 890

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YNILVSGN 8
           YN L+ GN
Sbjct: 742 YNYLIGGN 749
>NP_789787
          Length = 333

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ILVSGNA 9
           IL+SGNA
Sbjct: 296 ILISGNA 302
>NP_775882
          Length = 433

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   YNILVSGN 8
           Y++L+SG+
Sbjct: 95  YSVLISGD 102
>NP_001139661
          Length = 1815

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>NP_001139662
          Length = 1660

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>NP_683692
          Length = 3051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YNILVSG 7
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>NP_001120650
          Length = 983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 528 NVLVGGN 534
>NP_001275980
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 439 NVLVGGN 445
>NP_002550
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YNILVSGNA 9
           +++LV GNA
Sbjct: 305 FDVLVYGNA 313
>NP_060203
          Length = 975

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 520 NVLVGGN 526
>NP_060227
          Length = 2248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>NP_001275982
          Length = 480

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 439 NVLVGGN 445
>NP_001275981
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 395 NVLVGGN 401
>XP_006722564
          Length = 1628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>XP_006722563
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>XP_005266783
          Length = 2248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NILVSGNA 9
           NILV GN+
Sbjct: 419 NILVLGNS 426
>XP_006714215
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    YNILVSGN 8
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_006714214
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    YNILVSGN 8
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_005262915
          Length = 3544

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    YNILVSGN 8
            Y+I+VSG+
Sbjct: 3157 YHIIVSGS 3164
>XP_005248208
          Length = 3097

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YNILVSG 7
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_005248207
          Length = 3098

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YNILVSG 7
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_006714021
          Length = 3112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    YNILVSG 7
            Y++LVSG
Sbjct: 2008 YDVLVSG 2014
>XP_005272346
          Length = 539

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_005272345
          Length = 619

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_005272344
          Length = 624

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 528 NVLVGGN 534
>XP_006713955
          Length = 861

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 406 NVLVGGN 412
>XP_005272341
          Length = 894

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 439 NVLVGGN 445
>XP_005272340
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NILVSGN 8
           N+LV GN
Sbjct: 458 NVLVGGN 464
>NP_055806
          Length = 3526

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    YNILVSGN 8
            Y+I+VSG+
Sbjct: 3139 YHIIVSGS 3146
>NP_001001952
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YNILVSGN 8
          YN+ V GN
Sbjct: 36 YNVTVLGN 43
>NP_001243092
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ILVSGNA 9
           ILV GNA
Sbjct: 513 ILVKGNA 519
>NP_001243095
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ILVSGNA 9
           ILV GNA
Sbjct: 464 ILVKGNA 470
>NP_001157
          Length = 618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   ILVSGNA 9
           ILV GNA
Sbjct: 513 ILVKGNA 519
>NP_006609
          Length = 1544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YNILVSGNA 9
           YN+ +SG++
Sbjct: 182 YNLFLSGDS 190
>NP_976328
          Length = 911

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   YNILVSGN 8
           +N+L+SG+
Sbjct: 718 FNVLLSGS 725
>NP_006222
          Length = 2286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YNILVSGNA 9
           YN+   GNA
Sbjct: 244 YNVRYRGNA 252
>NP_060919
          Length = 1119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  NILVSGNA 9
          NIL+ GN+
Sbjct: 87 NILLEGNS 94
>NP_005305
          Length = 384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YNILVSGN 8
           YN+ V GN
Sbjct: 242 YNLPVEGN 249
>NP_001138871
          Length = 277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>NP_036296
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 239 DILVSGSA 246
>NP_001037835
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 142 YKIVIAGN 149
>NP_001575
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_006726852
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>XP_006723594
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>XP_006718368
          Length = 178

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_005253171
          Length = 182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_005253170
          Length = 196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          Y I+++GN
Sbjct: 12 YKIVIAGN 19
>XP_006718367
          Length = 220

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          Y I+++GN
Sbjct: 36 YKIVIAGN 43
>XP_005253169
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_005253168
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_005253167
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   YNILVSGN 8
           Y I+++GN
Sbjct: 110 YKIVIAGN 117
>XP_005251970
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 110 DILVSGSA 117
>XP_005251969
          Length = 389

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 174 DILVSGSA 181
>XP_006717114
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 206 DILVSGSA 213
>XP_005251967
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 239 DILVSGSA 246
>XP_006717113
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 271 DILVSGSA 278
>XP_006717112
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 271 DILVSGSA 278
>XP_005251965
          Length = 486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   NILVSGNA 9
           +ILVSG+A
Sbjct: 271 DILVSGSA 278
>XP_006710109
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          YN+ VSG+
Sbjct: 62 YNVEVSGS 69
>NP_001004474
          Length = 331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  YNILVSGN 8
          Y+I V+GN
Sbjct: 48 YSITVAGN 55
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.134    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 542,049
Number of extensions: 996
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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