Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              22     134
NP_001001419                                                           16    5631
NP_005894                                                              16    5631
NP_001001420                                                           16    5631
NP_789787                                                              16    5631
NP_056083                                                              16    5631
XP_005247302                                                           16    5631
NP_001243415                                                           16    7355
NP_001243417                                                           16    7355
NP_004478                                                              16    7355
NP_001243416                                                           16    7355
NP_005624                                                              16    7355
NP_114437                                                              16    7355
NP_660319                                                              16    7355
NP_055696                                                              16    7355
NP_001258745                                                           16    7355
NP_001094891                                                           16    7355
XP_005259809                                                           16    7355
XP_005259808                                                           16    7355
XP_006722715                                                           16    7355
XP_006722714                                                           16    7355
XP_006722713                                                           16    7355
XP_005259805                                                           16    7355
XP_006718153                                                           16    7355
XP_006713654                                                           16    7355
XP_006713653                                                           16    7355
XP_005247430                                                           16    7355
XP_005247429                                                           16    7355
XP_006713652                                                           16    7355
XP_006713651                                                           16    7355
XP_006713650                                                           16    7355
XP_005247428                                                           16    7355
XP_005264572                                                           16    7355
NP_653176                                                              16    7355
NP_001107578                                                           15    9605
NP_001245271                                                           15    9605
NP_001245269                                                           15    9605
NP_689582                                                              15    9605
NP_001245270                                                           15    9605
NP_001245272                                                           15    9605
NP_056132                                                              15    9605
NP_001269719                                                           15    9605
NP_055491                                                              15    9605
NP_037445                                                              15    9605
NP_001073944                                                           15    9605
NP_110451                                                              15    9605
NP_001018494                                                           15    9605
NP_001005404                                                           15    9605
NP_061897                                                              15    9605
NP_001004699                                                           15    9605
XP_006724301                                                           15    9605
XP_006724300                                                           15    9605
XP_006722971                                                           15    9605
XP_006722970                                                           15    9605
XP_005246602                                                           15    9605
XP_006712584                                                           15    9605
XP_005246601                                                           15    9605
XP_005246600                                                           15    9605
XP_006712098                                                           15    9605
XP_006712097                                                           15    9605
XP_005262667                                                           15    9605
XP_005262666                                                           15    9605
XP_006712037                                                           15    9605
XP_006712036                                                           15    9605
XP_006712035                                                           15    9605
XP_005262664                                                           15    9605
XP_005270500                                                           15    9605
XP_005270498                                                           15    9605
XP_005270497                                                           15    9605
>NP_002430
          Length = 1137

 Score = 21.6 bits (44), Expect =   134
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   YNHAFQAVT 9
           Y+HAFQAVT
Sbjct: 465 YSHAFQAVT 473
>NP_001001419
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NHAFQAV 8
           NH F+AV
Sbjct: 397 NHGFEAV 403
>NP_005894
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NHAFQAV 8
           NH F+AV
Sbjct: 397 NHGFEAV 403
>NP_001001420
          Length = 465

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NHAFQAV 8
           NH F+AV
Sbjct: 397 NHGFEAV 403
>NP_789787
          Length = 333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2  NHAFQAV 8
          NH++QA+
Sbjct: 89 NHSYQAI 95
>NP_056083
          Length = 2243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    YNHAFQAVT 9
            Y H F A+T
Sbjct: 1724 YLHTFMAIT 1732
>XP_005247302
          Length = 2248

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    YNHAFQAVT 9
            Y H F A+T
Sbjct: 1729 YLHTFMAIT 1737
>NP_001243415
          Length = 3269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 463 YNEGTQAVT 471
>NP_001243417
          Length = 3184

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 383 YNEGTQAVT 391
>NP_004478
          Length = 3259

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 458 YNEGTQAVT 466
>NP_001243416
          Length = 3225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 424 YNEGTQAVT 432
>NP_005624
          Length = 1333

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   YNHAFQAV 8
           Y HAF+ +
Sbjct: 510 YKHAFEII 517
>NP_114437
          Length = 1053

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           Y+H FQ  T
Sbjct: 766 YSHVFQIST 774
>NP_660319
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 152 YHHSFQS 158
>NP_055696
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NHAFQAVT 9
           N AF+AVT
Sbjct: 860 NTAFEAVT 867
>NP_001258745
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NHAFQAVT 9
           N AF+AVT
Sbjct: 860 NTAFEAVT 867
>NP_001094891
          Length = 1022

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   HAFQAVT 9
           H F+AVT
Sbjct: 958 HVFEAVT 964
>XP_005259809
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 152 YHHSFQS 158
>XP_005259808
          Length = 229

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 152 YHHSFQS 158
>XP_006722715
          Length = 383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  YNHAFQA 7
          Y+H+FQ+
Sbjct: 59 YHHSFQS 65
>XP_006722714
          Length = 420

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 96  YHHSFQS 102
>XP_006722713
          Length = 439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 115 YHHSFQS 121
>XP_005259805
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YNHAFQA 7
           Y+H+FQ+
Sbjct: 152 YHHSFQS 158
>XP_006718153
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   NHAFQAVT 9
           N AF+AVT
Sbjct: 860 NTAFEAVT 867
>XP_006713654
          Length = 3189

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 383 YNEGTQAVT 391
>XP_006713653
          Length = 3223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 422 YNEGTQAVT 430
>XP_005247430
          Length = 3228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 422 YNEGTQAVT 430
>XP_005247429
          Length = 3230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 424 YNEGTQAVT 432
>XP_006713652
          Length = 3263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 457 YNEGTQAVT 465
>XP_006713651
          Length = 3264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 458 YNEGTQAVT 466
>XP_006713650
          Length = 3264

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 463 YNEGTQAVT 471
>XP_005247428
          Length = 3269

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YNHAFQAVT 9
           YN   QAVT
Sbjct: 463 YNEGTQAVT 471
>XP_005264572
          Length = 1318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   YNHAFQAV 8
           Y HAF+ +
Sbjct: 510 YKHAFEII 517
>NP_653176
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YNHAFQAV 8
           Y H FQ V
Sbjct: 573 YQHVFQKV 580
>NP_001107578
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 557 YNRAFQ 562
>NP_001245271
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 521 YNRAFQ 526
>NP_001245269
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 556 YNRAFQ 561
>NP_689582
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 509 YNRAFQ 514
>NP_001245270
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 524 YNRAFQ 529
>NP_001245272
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 489 YNRAFQ 494
>NP_056132
          Length = 1064

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>NP_001269719
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>NP_055491
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NHAFQAV 8
           NH FQA+
Sbjct: 129 NHDFQAL 135
>NP_037445
          Length = 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  YNHAFQA 7
          Y HAF++
Sbjct: 90 YEHAFES 96
>NP_001073944
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NHAFQAVT 9
           NH+FQ  T
Sbjct: 336 NHSFQKKT 343
>NP_110451
          Length = 627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   YNHAFQ 6
           Y+H+FQ
Sbjct: 164 YHHSFQ 169
>NP_001018494
          Length = 1188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NHAFQAV 8
           NH FQA+
Sbjct: 129 NHDFQAL 135
>NP_001005404
          Length = 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  YNHAFQA 7
          Y HAF++
Sbjct: 90 YEHAFES 96
>NP_061897
          Length = 2071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    YNHAFQAV 8
            Y HAF+ V
Sbjct: 2017 YPHAFKTV 2024
>NP_001004699
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 5/8 (62%)

Query: 1   YNHAFQAV 8
           Y H  QAV
Sbjct: 218 YGHVLQAV 225
>XP_006724301
          Length = 119

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1  YNHAFQA 7
          Y HAF++
Sbjct: 90 YEHAFES 96
>XP_006724300
          Length = 242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   YNHAFQA 7
           Y HAF++
Sbjct: 213 YEHAFES 219
>XP_006722971
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   YNHAFQ 6
           Y+H+FQ
Sbjct: 157 YHHSFQ 162
>XP_006722970
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   YNHAFQ 6
           Y+H+FQ
Sbjct: 157 YHHSFQ 162
>XP_005246602
          Length = 651

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NHAFQAVT 9
           NH+FQ  T
Sbjct: 336 NHSFQKKT 343
>XP_006712584
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NHAFQAVT 9
           NH+FQ  T
Sbjct: 336 NHSFQKKT 343
>XP_005246601
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NHAFQAVT 9
           NH+FQ  T
Sbjct: 336 NHSFQKKT 343
>XP_005246600
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   NHAFQAVT 9
           NH+FQ  T
Sbjct: 336 NHSFQKKT 343
>XP_006712098
          Length = 2059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    YNHAFQAV 8
            Y HAF+ V
Sbjct: 2005 YPHAFKTV 2012
>XP_006712097
          Length = 2070

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    YNHAFQAV 8
            Y HAF+ V
Sbjct: 2016 YPHAFKTV 2023
>XP_005262667
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_005262666
          Length = 987

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_006712037
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_006712036
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_006712035
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_005262664
          Length = 1066

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2 NHAFQAV 8
         NH FQA+
Sbjct: 2 NHDFQAL 8
>XP_005270500
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 477 YNRAFQ 482
>XP_005270498
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 509 YNRAFQ 514
>XP_005270497
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YNHAFQ 6
           YN AFQ
Sbjct: 525 YNRAFQ 530
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.126    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,026
Number of extensions: 503
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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