Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_073713                                                              18    1482
NP_000912                                                              17    2528
XP_006719149                                                           17    2528
NP_775105                                                              17    3301
NP_001036148                                                           17    3301
XP_006715506                                                           17    3301
XP_006715505                                                           17    3301
XP_006715504                                                           17    3301
XP_006715503                                                           17    3301
XP_006715502                                                           17    3301
NP_004658                                                              16    7355
NP_001957                                                              16    7355
NP_065203                                                              16    7355
NP_001159887                                                           16    7355
XP_005259442                                                           16    7355
XP_005259441                                                           16    7355
XP_006720790                                                           16    7355
XP_005268334                                                           16    7355
XP_005268333                                                           16    7355
XP_006720789                                                           16    7355
XP_005273778                                                           16    7355
XP_005273777                                                           16    7355
XP_006713588                                                           16    7355
NP_291035                                                              16    7355
NP_001034760                                                           16    7355
NP_001034762                                                           16    7355
NP_001138933                                                           16    7355
NP_001138934                                                           16    7355
NP_001034761                                                           16    7355
NP_001138935                                                           16    7355
NP_001158184                                                           15    9605
NP_000472                                                              15    9605
NP_001158182                                                           15    9605
NP_001278295                                                           15    9605
NP_001273171                                                           15    9605
NP_001511                                                              15    9605
NP_001157413                                                           15    9605
NP_001158183                                                           15    9605
NP_848654                                                              15    9605
NP_055429                                                              15    9605
NP_116182                                                              15    9605
NP_001129965                                                           15    9605
NP_001274738                                                           15    9605
NP_001274737                                                           15    9605
NP_001171922                                                           15    9605
XP_006724409                                                           15    9605
XP_005261851                                                           15    9605
XP_005261850                                                           15    9605
XP_006721105                                                           15    9605
XP_006719916                                                           15    9605
XP_006719915                                                           15    9605
XP_006719914                                                           15    9605
XP_005266530                                                           15    9605
XP_006719913                                                           15    9605
XP_006719912                                                           15    9605
XP_006719911                                                           15    9605
XP_006719910                                                           15    9605
XP_006719909                                                           15    9605
XP_006712032                                                           15    9605
XP_005271342                                                           15    9605
NP_112567                                                              15    9605
NP_001138678                                                           15    9605
>NP_073713
          Length = 985

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y LQAGVAL
Sbjct: 455 YPLQAGVAL 463
>NP_000912
          Length = 1141

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           YLL+AGV L
Sbjct: 149 YLLRAGVRL 157
>XP_006719149
          Length = 1087

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           YLL+AGV L
Sbjct: 149 YLLRAGVRL 157
>NP_775105
          Length = 1659

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>NP_001036148
          Length = 1683

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>XP_006715506
          Length = 1507

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>XP_006715505
          Length = 1673

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>XP_006715504
          Length = 1683

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>XP_006715503
          Length = 1707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>XP_006715502
          Length = 1707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   YLLQAGVA 8
           YLL+AG+A
Sbjct: 215 YLLEAGLA 222
>NP_004658
          Length = 4834

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            Y+L+AG AL
Sbjct: 2324 YILKAGRAL 2332
>NP_001957
          Length = 723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           YLLQ+G A
Sbjct: 258 YLLQSGQA 265
>NP_065203
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 149 YVLLAGMAL 157
>NP_001159887
          Length = 627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           YLLQ+G A
Sbjct: 162 YLLQSGQA 169
>XP_005259442
          Length = 283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 136 YVLVAGLAL 144
>XP_005259441
          Length = 294

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 164 YVLVAGLAL 172
>XP_006720790
          Length = 4748

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            Y+L+AG AL
Sbjct: 2238 YILKAGRAL 2246
>XP_005268334
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            Y+L+AG AL
Sbjct: 2286 YILKAGRAL 2294
>XP_005268333
          Length = 4796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            Y+L+AG AL
Sbjct: 2286 YILKAGRAL 2294
>XP_006720789
          Length = 4829

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            Y+L+AG AL
Sbjct: 2319 YILKAGRAL 2327
>XP_005273778
          Length = 241

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 149 YVLLAGMAL 157
>XP_005273777
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 149 YVLLAGMAL 157
>XP_006713588
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  YLLQAGVA 8
          YLLQ+G A
Sbjct: 50 YLLQSGQA 57
>NP_291035
          Length = 283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 136 YVLVAGLAL 144
>NP_001034760
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 152 YVLVAGLAL 160
>NP_001034762
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 164 YVLVAGLAL 172
>NP_001138933
          Length = 297

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 150 YVLVAGLAL 158
>NP_001138934
          Length = 283

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 136 YVLVAGLAL 144
>NP_001034761
          Length = 314

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 167 YVLVAGLAL 175
>NP_001138935
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           Y+L AG+AL
Sbjct: 164 YVLVAGLAL 172
>NP_001158184
          Length = 386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAGVA 8
           +LQAGVA
Sbjct: 190 VLQAGVA 196
>NP_000472
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAGVA 8
           +LQAGVA
Sbjct: 190 VLQAGVA 196
>NP_001158182
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAGVA 8
           +LQAGVA
Sbjct: 146 VLQAGVA 152
>NP_001278295
          Length = 790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  LLQAGVA 8
          LLQAG+A
Sbjct: 27 LLQAGLA 33
>NP_001273171
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           Y+L AG+A
Sbjct: 296 YMLNAGLA 303
>NP_001511
          Length = 2109

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           Y+L AG+A
Sbjct: 296 YMLNAGLA 303
>NP_001157413
          Length = 1257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YLLQAG 6
           YL+QAG
Sbjct: 942 YLIQAG 947
>NP_001158183
          Length = 347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQAGVA 8
           +LQAGVA
Sbjct: 134 VLQAGVA 140
>NP_848654
          Length = 812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YLLQAG 6
           YL+QAG
Sbjct: 497 YLIQAG 502
>NP_055429
          Length = 1843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YLLQAGVA 8
            Y+LQ G+A
Sbjct: 1466 YVLQGGLA 1473
>NP_116182
          Length = 530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLLQAGV 7
           YLL AGV
Sbjct: 242 YLLAAGV 248
>NP_001129965
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLLQAGV 7
           YLL AGV
Sbjct: 255 YLLAAGV 261
>NP_001274738
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLLQAGV 7
           YLL AGV
Sbjct: 203 YLLAAGV 209
>NP_001274737
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  YLLQAGV 7
          YLL AGV
Sbjct: 86 YLLAAGV 92
>NP_001171922
          Length = 1619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1091 YLIKKGLAL 1099
>XP_006724409
          Length = 1806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  YLLQAGVA 8
          Y LQAG A
Sbjct: 32 YFLQAGEA 39
>XP_005261851
          Length = 1806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  YLLQAGVA 8
          Y LQAG A
Sbjct: 32 YFLQAGEA 39
>XP_005261850
          Length = 1806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  YLLQAGVA 8
          Y LQAG A
Sbjct: 32 YFLQAGEA 39
>XP_006721105
          Length = 2046

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           Y+L AG+A
Sbjct: 296 YMLNAGLA 303
>XP_006719916
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YLLQAGVAL 9
           YL++ G+AL
Sbjct: 954 YLIKKGLAL 962
>XP_006719915
          Length = 1531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1003 YLIKKGLAL 1011
>XP_006719914
          Length = 1639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1111 YLIKKGLAL 1119
>XP_005266530
          Length = 1643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1115 YLIKKGLAL 1123
>XP_006719913
          Length = 1650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1164 YLIKKGLAL 1172
>XP_006719912
          Length = 1672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1144 YLIKKGLAL 1152
>XP_006719911
          Length = 1688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1160 YLIKKGLAL 1168
>XP_006719910
          Length = 1692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1164 YLIKKGLAL 1172
>XP_006719909
          Length = 1692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1164 YLIKKGLAL 1172
>XP_006712032
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YLLQAGVA 8
           Y+LQ G+A
Sbjct: 624 YVLQGGLA 631
>XP_005271342
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   YLLQAGV 7
           YLL AGV
Sbjct: 240 YLLAAGV 246
>NP_112567
          Length = 1623

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YLLQAGVAL 9
            YL++ G+AL
Sbjct: 1095 YLIKKGLAL 1103
>NP_001138678
          Length = 1806

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  YLLQAGVA 8
          Y LQAG A
Sbjct: 32 YFLQAGEA 39
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.145    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 386,123
Number of extensions: 700
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package