Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_071754                                                              19     665
NP_001185763                                                           19     665
NP_001002810                                                           19     665
NP_055459                                                              19     665
NP_001182189                                                           19     665
NP_001002812                                                           19     665
NP_001182190                                                           19     665
XP_006711719                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
NP_060719                                                              17    3301
NP_001258968                                                           17    3301
NP_001011649                                                           17    3301
XP_006717248                                                           17    3301
XP_006717247                                                           17    3301
XP_006717246                                                           17    3301
XP_006717245                                                           17    3301
XP_006717244                                                           17    3301
XP_006717243                                                           17    3301
XP_006717242                                                           17    3301
NP_004953                                                              17    4312
XP_006717825                                                           17    4312
NP_001124295                                                           16    7355
NP_001370                                                              16    7355
NP_055693                                                              16    7355
XP_006723127                                                           16    7355
XP_006722744                                                           16    7355
NP_689816                                                              16    7355
NP_000811                                                              15    9605
NP_001137417                                                           15    9605
NP_001137418                                                           15    9605
NP_001276081                                                           15    9605
NP_001170990                                                           15    9605
NP_001276082                                                           15    9605
NP_001276083                                                           15    9605
NP_775966                                                              15    9605
NP_056386                                                              15    9605
NP_055907                                                              15    9605
NP_001192                                                              15    9605
XP_005255242                                                           15    9605
XP_005255241                                                           15    9605
XP_005255240                                                           15    9605
XP_005255239                                                           15    9605
XP_006715520                                                           15    9605
XP_006714354                                                           15    9605
NP_001093879                                                           15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>NP_071754
          Length = 310

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 182 YKRNIELKV 190
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>NP_001002810
          Length = 173

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>NP_001182189
          Length = 141

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 13 YKRNIELKV 21
>NP_001002812
          Length = 969

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>NP_001182190
          Length = 176

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 48 YKRNIELKV 56
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 45 YKRNIELKV 53
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YKRNIVLKV 9
          YKRNI LKV
Sbjct: 48 YKRNIELKV 56
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YKRNIVLKV 9
           YKRNI LKV
Sbjct: 111 YKRNIELKV 119
>NP_060719
          Length = 1893

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>NP_001258968
          Length = 1663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>NP_001011649
          Length = 1814

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717248
          Length = 1664

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717247
          Length = 1670

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717246
          Length = 1820

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717245
          Length = 1861

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717244
          Length = 1867

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 100 YKTNIELKV 108
>XP_006717243
          Length = 1889

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  YKRNIVLKV 9
          YK NI LKV
Sbjct: 90 YKTNIELKV 98
>XP_006717242
          Length = 1898

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   YKRNIVLKV 9
           YK NI LKV
Sbjct: 99  YKTNIELKV 107
>NP_004953
          Length = 478

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           RN+VLKV
Sbjct: 460 RNVVLKV 466
>XP_006717825
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           RN+VLKV
Sbjct: 459 RNVVLKV 465
>NP_001124295
          Length = 1632

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    YKRNIVLKV 9
            +KR++VLK+
Sbjct: 1290 FKRSMVLKL 1298
>NP_001370
          Length = 1616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    YKRNIVLKV 9
            +KR++VLK+
Sbjct: 1274 FKRSMVLKL 1282
>NP_055693
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YKRNIVLK 8
           Y RNIV K
Sbjct: 214 YSRNIVKK 221
>XP_006723127
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YKRNIVL 7
           YKRN+++
Sbjct: 628 YKRNLIV 634
>XP_006722744
          Length = 1495

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    YKRNIVLKV 9
            +KR++VLK+
Sbjct: 1153 FKRSMVLKL 1161
>NP_689816
          Length = 616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YKRNIVL 7
           YKRN+++
Sbjct: 597 YKRNLIV 603
>NP_000811
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           RN+V+KV
Sbjct: 389 RNLVIKV 395
>NP_001137417
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           RN+V+KV
Sbjct: 116 RNLVIKV 122
>NP_001137418
          Length = 379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  RNIVLKV 9
          RN+V+KV
Sbjct: 90 RNLVIKV 96
>NP_001276081
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   YKRNIVL 7
           Y RNI+L
Sbjct: 134 YPRNIIL 140
>NP_001170990
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   YKRNIVL 7
           Y RNI+L
Sbjct: 231 YPRNIIL 237
>NP_001276082
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   YKRNIVL 7
           Y RNI+L
Sbjct: 134 YPRNIIL 140
>NP_001276083
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  YKRNIVL 7
          Y RNI+L
Sbjct: 93 YPRNIIL 99
>NP_775966
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KRNIVLK 8
          K+NI+LK
Sbjct: 7  KQNIILK 13
>NP_056386
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RNIVLKV 9
            RNI+LK+
Sbjct: 1072 RNIILKL 1078
>NP_055907
          Length = 3661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KRNIVLK 8
            +RN+VLK
Sbjct: 3285 RRNLVLK 3291
>NP_001192
          Length = 472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           +N+VLKV
Sbjct: 454 KNVVLKV 460
>XP_005255242
          Length = 3609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KRNIVLK 8
            +RN+VLK
Sbjct: 3233 RRNLVLK 3239
>XP_005255241
          Length = 3637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KRNIVLK 8
            +RN+VLK
Sbjct: 3261 RRNLVLK 3267
>XP_005255240
          Length = 3663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KRNIVLK 8
            +RN+VLK
Sbjct: 3287 RRNLVLK 3293
>XP_005255239
          Length = 3689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    KRNIVLK 8
            +RN+VLK
Sbjct: 3313 RRNLVLK 3319
>XP_006715520
          Length = 1056

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RNIVLKV 9
            RNI+LK+
Sbjct: 1016 RNIILKL 1022
>XP_006714354
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RNIVLKV 9
           +N+VLKV
Sbjct: 421 KNVVLKV 427
>NP_001093879
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    RNIVLKV 9
            RNI+LK+
Sbjct: 1065 RNIILKL 1071
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.147    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 380,973
Number of extensions: 743
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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