Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003391                                                              18    1482
NP_055954                                                              18    1482
NP_775790                                                              18    1482
XP_005251234                                                           18    1482
XP_005251233                                                           18    1482
XP_006712159                                                           18    1482
XP_006712158                                                           18    1482
XP_005264603                                                           18    1482
XP_005264601                                                           18    1482
XP_006712157                                                           18    1482
XP_006710542                                                           18    1482
XP_006710541                                                           18    1482
NP_001026855                                                           18    1935
NP_005417                                                              18    1935
XP_005273303                                                           18    1935
NP_001007024                                                           17    2528
NP_001229431                                                           17    2528
NP_061027                                                              17    2528
NP_477352                                                              17    2528
XP_005261692                                                           17    2528
XP_005261691                                                           17    2528
NP_060124                                                              17    4312
NP_001180236                                                           17    4312
NP_114129                                                              16    5631
NP_004529                                                              16    5631
NP_938205                                                              16    5631
NP_001127848                                                           16    5631
NP_001127847                                                           16    5631
NP_061957                                                              16    5631
NP_037413                                                              16    5631
XP_005260739                                                           16    5631
NP_009175                                                              16    7355
NP_079375                                                              16    7355
NP_689687                                                              16    7355
NP_055608                                                              16    7355
NP_055696                                                              16    7355
NP_001258745                                                           16    7355
XP_006721642                                                           16    7355
XP_006721641                                                           16    7355
XP_006721640                                                           16    7355
XP_006718153                                                           16    7355
NP_001188386                                                           15    9605
NP_938207                                                              15    9605
NP_112562                                                              15    9605
NP_001036017                                                           15    9605
NP_001139642                                                           15    9605
NP_001036018                                                           15    9605
NP_001139643                                                           15    9605
NP_001139641                                                           15    9605
NP_001803                                                              15    9605
NP_001262                                                              15    9605
NP_060217                                                              15    9605
NP_065741                                                              15    9605
XP_006722041                                                           15    9605
XP_005257576                                                           15    9605
XP_006722040                                                           15    9605
XP_006722039                                                           15    9605
XP_005257575                                                           15    9605
XP_005248375                                                           15    9605
XP_006714128                                                           15    9605
XP_006714127                                                           15    9605
NP_001034585                                                           15    9605
NP_570603                                                              15    9605
NP_055018                                                              15    9605
NP_060504                                                              15    9605
>NP_003391
          Length = 1071

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           YK LN+P+F
Sbjct: 252 YKFLNVPMF 260
>NP_055954
          Length = 355

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KQLNLPLF 9
           K+LNLP+F
Sbjct: 128 KKLNLPMF 135
>NP_775790
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           Y+QLNL +F
Sbjct: 100 YRQLNLDMF 108
>XP_005251234
          Length = 317

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           Y+QLNL +F
Sbjct: 100 YRQLNLDMF 108
>XP_005251233
          Length = 354

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           Y+QLNL +F
Sbjct: 100 YRQLNLDMF 108
>XP_006712159
          Length = 904

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  YKQLNLPLF 9
          YK LN+P+F
Sbjct: 85 YKFLNVPMF 93
>XP_006712158
          Length = 904

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  YKQLNLPLF 9
          YK LN+P+F
Sbjct: 85 YKFLNVPMF 93
>XP_005264603
          Length = 940

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           YK LN+P+F
Sbjct: 121 YKFLNVPMF 129
>XP_005264601
          Length = 1056

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           YK LN+P+F
Sbjct: 237 YKFLNVPMF 245
>XP_006712157
          Length = 1071

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           YK LN+P+F
Sbjct: 252 YKFLNVPMF 260
>XP_006710542
          Length = 359

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KQLNLPLF 9
           K+LNLP+F
Sbjct: 128 KKLNLPMF 135
>XP_006710541
          Length = 382

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   KQLNLPLF 9
           K+LNLP+F
Sbjct: 128 KKLNLPMF 135
>NP_001026855
          Length = 1134

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           KQ+NLP F
Sbjct: 513 KQINLPYF 520
>NP_005417
          Length = 1005

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           KQ+NLP F
Sbjct: 384 KQINLPYF 391
>XP_005273303
          Length = 1125

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           KQ+NLP F
Sbjct: 504 KQINLPYF 511
>NP_001007024
          Length = 309

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  YKQLNLP 7
          YKQLN P
Sbjct: 72 YKQLNCP 78
>NP_001229431
          Length = 146

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  YKQLNLP 7
          YKQLN P
Sbjct: 72 YKQLNCP 78
>NP_061027
          Length = 4599

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YKQLNLP 7
            YKQL+LP
Sbjct: 4167 YKQLDLP 4173
>NP_477352
          Length = 2102

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           YK+ N+PL
Sbjct: 319 YKEFNIPL 326
>XP_005261692
          Length = 1854

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           YK+ N+PL
Sbjct: 347 YKEFNIPL 354
>XP_005261691
          Length = 2099

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           YK+ N+PL
Sbjct: 347 YKEFNIPL 354
>NP_060124
          Length = 1589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 KQLNLP 7
         KQLNLP
Sbjct: 3 KQLNLP 8
>NP_001180236
          Length = 1589

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2 KQLNLP 7
         KQLNLP
Sbjct: 3 KQLNLP 8
>NP_114129
          Length = 929

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           K+L LPLF
Sbjct: 659 KELALPLF 666
>NP_004529
          Length = 506

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YKQLNLPLF 9
           Y +LN PL+
Sbjct: 136 YAELNKPLY 144
>NP_938205
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YKQLNLPL 8
           YK  NLPL
Sbjct: 522 YKNPNLPL 529
>NP_001127848
          Length = 371

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YKQLNLPLF 9
          YK+L LP +
Sbjct: 22 YKELKLPSY 30
>NP_001127847
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YKQLNLPLF 9
          YK+L LP +
Sbjct: 22 YKELKLPSY 30
>NP_061957
          Length = 372

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YKQLNLPLF 9
          YK+L LP +
Sbjct: 22 YKELKLPSY 30
>NP_037413
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YKQLNLPL 8
           YK  NLPL
Sbjct: 522 YKNPNLPL 529
>XP_005260739
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YKQLNLPL 8
           YK  NLPL
Sbjct: 522 YKNPNLPL 529
>NP_009175
          Length = 134

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YKQLNLPLF 9
           ++QL+LP F
Sbjct: 99  HRQLSLPRF 107
>NP_079375
          Length = 1217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           +QL LPL+
Sbjct: 460 RQLGLPLY 467
>NP_689687
          Length = 215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YKQLNLPL 8
           YK L +PL
Sbjct: 139 YKNLRIPL 146
>NP_055608
          Length = 686

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           ++QLN PL
Sbjct: 235 FRQLNSPL 242
>NP_055696
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           Y Q++LPL
Sbjct: 453 YNQVSLPL 460
>NP_001258745
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           Y Q++LPL
Sbjct: 453 YNQVSLPL 460
>XP_006721642
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           +QL LPL+
Sbjct: 460 RQLGLPLY 467
>XP_006721641
          Length = 1140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           +QL LPL+
Sbjct: 460 RQLGLPLY 467
>XP_006721640
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   KQLNLPLF 9
           +QL LPL+
Sbjct: 417 RQLGLPLY 424
>XP_006718153
          Length = 1040

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YKQLNLPL 8
           Y Q++LPL
Sbjct: 453 YNQVSLPL 460
>NP_001188386
          Length = 1497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 273 KELNLP 278
>NP_938207
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 267 KELNLP 272
>NP_112562
          Length = 1451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 267 KELNLP 272
>NP_001036017
          Length = 274

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KQLNLPL 8
           K+LNLP+
Sbjct: 138 KRLNLPV 144
>NP_001139642
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KQLNLPL 8
           K+LNLP+
Sbjct: 117 KRLNLPV 123
>NP_001036018
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KQLNLPL 8
           K+LNLP+
Sbjct: 138 KRLNLPV 144
>NP_001139643
          Length = 281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KQLNLPL 8
           K+LNLP+
Sbjct: 138 KRLNLPV 144
>NP_001139641
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KQLNLPL 8
           K+LNLP+
Sbjct: 138 KRLNLPV 144
>NP_001803
          Length = 943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YKQLNLPLF 9
           YK L+ P F
Sbjct: 859 YKTLDTPFF 867
>NP_001262
          Length = 1828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1    YKQLNLPL 8
            YK+  LPL
Sbjct: 1143 YKKFGLPL 1150
>NP_060217
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YKQLNLPL 8
            YK ++LPL
Sbjct: 1661 YKTVSLPL 1668
>NP_065741
          Length = 2617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    YKQLNLPL 8
            YK ++LPL
Sbjct: 1661 YKTVSLPL 1668
>XP_006722041
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 270 KELNLP 275
>XP_005257576
          Length = 1454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 270 KELNLP 275
>XP_006722040
          Length = 1466

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 270 KELNLP 275
>XP_006722039
          Length = 1491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 267 KELNLP 272
>XP_005257575
          Length = 1494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   KQLNLP 7
           K+LNLP
Sbjct: 270 KELNLP 275
>XP_005248375
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQLNLPLF 9
           +Q N PLF
Sbjct: 407 RQFNKPLF 414
>XP_006714128
          Length = 730

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YKQLNLPLF 9
           YK L+ P F
Sbjct: 646 YKTLDTPFF 654
>XP_006714127
          Length = 935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   YKQLNLPLF 9
           YK L+ P F
Sbjct: 851 YKTLDTPFF 859
>NP_001034585
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  QLNLPL 8
          QLN+PL
Sbjct: 40 QLNMPL 45
>NP_570603
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YKQLNLP 7
           +KQL+LP
Sbjct: 857 WKQLSLP 863
>NP_055018
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YKQLNLP 7
           +KQL+LP
Sbjct: 879 WKQLSLP 885
>NP_060504
          Length = 654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   KQLNLPLF 9
           +Q N PLF
Sbjct: 408 RQFNKPLF 415
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.153    0.472 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 681,768
Number of extensions: 1223
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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