Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              21     229
NP_001075109                                                           21     229
NP_061993                                                              17    2528
NP_060395                                                              17    3301
XP_006716870                                                           17    3301
XP_006716869                                                           17    3301
XP_006716868                                                           17    3301
XP_006716867                                                           17    3301
NP_620177                                                              16    5631
NP_000910                                                              16    5631
NP_620121                                                              16    5631
NP_001170777                                                           16    5631
XP_006714701                                                           16    5631
XP_006714700                                                           16    5631
XP_006714699                                                           16    5631
XP_006714698                                                           16    5631
XP_006714697                                                           16    5631
XP_006714696                                                           16    5631
XP_006714695                                                           16    5631
NP_000126                                                              16    7355
NP_003838                                                              16    7355
NP_001258501                                                           16    7355
NP_001128563                                                           16    7355
NP_001128564                                                           16    7355
NP_663625                                                              16    7355
NP_001273096                                                           16    7355
NP_001124382                                                           16    7355
NP_001257295                                                           16    7355
NP_892121                                                              16    7355
NP_079164                                                              16    7355
NP_056311                                                              16    7355
NP_001159694                                                           16    7355
XP_005256351                                                           16    7355
XP_006721231                                                           16    7355
XP_006721230                                                           16    7355
XP_005274182                                                           16    7355
XP_005252857                                                           16    7355
XP_006718211                                                           16    7355
NP_003956                                                              16    7355
NP_002213                                                              15    9605
NP_001093422                                                           15    9605
NP_001978                                                              15    9605
NP_001161744                                                           15    9605
NP_055054                                                              15    9605
NP_056145                                                              15    9605
NP_001271247                                                           15    9605
NP_001271246                                                           15    9605
NP_066015                                                              15    9605
NP_001241661                                                           15    9605
NP_001116836                                                           15    9605
NP_001138940                                                           15    9605
NP_077300                                                              15    9605
NP_001128573                                                           15    9605
XP_005261795                                                           15    9605
XP_005261794                                                           15    9605
XP_005258381                                                           15    9605
XP_006722580                                                           15    9605
XP_006722579                                                           15    9605
XP_005258380                                                           15    9605
XP_006713199                                                           15    9605
XP_006713198                                                           15    9605
XP_006713197                                                           15    9605
XP_005265167                                                           15    9605
XP_006713196                                                           15    9605
XP_006713195                                                           15    9605
XP_005265166                                                           15    9605
XP_006713194                                                           15    9605
NP_001138567                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YFYSLLSET 9
            YFYSL SET
Sbjct: 1558 YFYSLFSET 1566
>NP_001075109
          Length = 4097

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YFYSLLSET 9
            YFYSL SET
Sbjct: 1558 YFYSLFSET 1566
>NP_061993
          Length = 801

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LL+ET
Sbjct: 401 FYTLLTET 408
>NP_060395
          Length = 1909

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LLS+T
Sbjct: 615 FYTLLSKT 622
>XP_006716870
          Length = 1456

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LLS+T
Sbjct: 113 FYTLLSKT 120
>XP_006716869
          Length = 1722

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LLS+T
Sbjct: 379 FYTLLSKT 386
>XP_006716868
          Length = 1894

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LLS+T
Sbjct: 615 FYTLLSKT 622
>XP_006716867
          Length = 1958

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   FYSLLSET 9
           FY+LLS+T
Sbjct: 615 FYTLLSKT 622
>NP_620177
          Length = 887

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>NP_000910
          Length = 974

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>NP_620121
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>NP_001170777
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714701
          Length = 905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714700
          Length = 906

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714699
          Length = 972

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714698
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714697
          Length = 973

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714696
          Length = 974

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>XP_006714695
          Length = 974

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   FYSLLSE 8
           FYSLLS+
Sbjct: 390 FYSLLSK 396
>NP_000126
          Length = 1455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FYSLLS 7
            FYSLLS
Sbjct: 1335 FYSLLS 1340
>NP_003838
          Length = 247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YFYSLL 6
           Y+YSLL
Sbjct: 127 YYYSLL 132
>NP_001258501
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YFYSLL 6
           Y+YSLL
Sbjct: 96  YYYSLL 101
>NP_001128563
          Length = 361

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FYSLLS 7
          FYSLLS
Sbjct: 41 FYSLLS 46
>NP_001128564
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FYSLLS 7
          FYSLLS
Sbjct: 41 FYSLLS 46
>NP_663625
          Length = 334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  FYSLLS 7
          FYSLLS
Sbjct: 14 FYSLLS 19
>NP_001273096
          Length = 1424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FYSLLS 7
            FYSLLS
Sbjct: 1335 FYSLLS 1340
>NP_001124382
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFYSLLSET 9
           YF  L SET
Sbjct: 122 YFVGLYSET 130
>NP_001257295
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFYSLLSET 9
           YF S++S+T
Sbjct: 221 YFNSVISDT 229
>NP_892121
          Length = 1147

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFYSLLSE 8
           +FY +LSE
Sbjct: 558 HFYEVLSE 565
>NP_079164
          Length = 746

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFYSLLSET 9
           YF S++S+T
Sbjct: 249 YFNSVISDT 257
>NP_056311
          Length = 1812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFYSLLSE 8
           +FY +LSE
Sbjct: 558 HFYEVLSE 565
>NP_001159694
          Length = 950

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  YFYSLL 6
          Y+YSLL
Sbjct: 65 YYYSLL 70
>XP_005256351
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FYSLLS 7
            FYSLLS
Sbjct: 1335 FYSLLS 1340
>XP_006721231
          Length = 1114

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FYSLLS 7
           FYSLLS
Sbjct: 994 FYSLLS 999
>XP_006721230
          Length = 1412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    FYSLLS 7
            FYSLLS
Sbjct: 1292 FYSLLS 1297
>XP_005274182
          Length = 966

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  YFYSLL 6
          Y+YSLL
Sbjct: 81 YYYSLL 86
>XP_005252857
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FYSLLS 7
           FYSLLS
Sbjct: 130 FYSLLS 135
>XP_006718211
          Length = 450

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FYSLLS 7
           FYSLLS
Sbjct: 130 FYSLLS 135
>NP_003956
          Length = 344

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFYSLLSET 9
           YF  L SET
Sbjct: 110 YFVGLYSET 118
>NP_002213
          Length = 2695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2356 FFYSLL 2361
>NP_001093422
          Length = 2710

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2371 FFYSLL 2376
>NP_001978
          Length = 452

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           Y Y LLS++
Sbjct: 344 YVYQLLSDS 352
>NP_001161744
          Length = 2743

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2404 FFYSLL 2409
>NP_055054
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YFYSLLSE 8
           Y Y L+SE
Sbjct: 335 YIYRLMSE 342
>NP_056145
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YFYSLLSE 8
           YF SLL E
Sbjct: 465 YFRSLLDE 472
>NP_001271247
          Length = 321

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>NP_001271246
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>NP_066015
          Length = 2579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           Y Y+LLS +
Sbjct: 396 YIYALLSSS 404
>NP_001241661
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YFYSLLSE 8
           YF SLL E
Sbjct: 465 YFRSLLDE 472
>NP_001116836
          Length = 366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFYSLLSE 8
           ++YSLL E
Sbjct: 316 FWYSLLKE 323
>NP_001138940
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YFYSLLSE 8
           YF SLL E
Sbjct: 465 YFRSLLDE 472
>NP_077300
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>NP_001128573
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>XP_005261795
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>XP_005261794
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           YF SL +ET
Sbjct: 184 YFSSLRNET 192
>XP_005258381
          Length = 2224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFYSLLSET 9
          Y Y+LLS +
Sbjct: 41 YIYALLSSS 49
>XP_006722580
          Length = 2532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           Y Y+LLS +
Sbjct: 396 YIYALLSSS 404
>XP_006722579
          Length = 2544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           Y Y+LLS +
Sbjct: 396 YIYALLSSS 404
>XP_005258380
          Length = 2578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFYSLLSET 9
           Y Y+LLS +
Sbjct: 396 YIYALLSSS 404
>XP_006713199
          Length = 2695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2356 FFYSLL 2361
>XP_006713198
          Length = 2699

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2360 FFYSLL 2365
>XP_006713197
          Length = 2712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2373 FFYSLL 2378
>XP_005265167
          Length = 2719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2380 FFYSLL 2385
>XP_006713196
          Length = 2721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2382 FFYSLL 2387
>XP_006713195
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2388 FFYSLL 2393
>XP_005265166
          Length = 2735

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2396 FFYSLL 2401
>XP_006713194
          Length = 2736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    YFYSLL 6
            +FYSLL
Sbjct: 2397 FFYSLL 2402
>NP_001138567
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FYSLLSET 9
           F+SLLS T
Sbjct: 98  FFSLLSVT 105
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.135    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 486,722
Number of extensions: 863
Number of successful extensions: 68
Number of sequences better than 10000.0: 68
Number of HSP's gapped: 68
Number of HSP's successfully gapped: 68
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

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