Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006501                                                              18    1135
NP_115758                                                              17    2528
NP_006149                                                              17    4312
NP_002604                                                              17    4312
NP_001248745                                                           17    4312
XP_005255413                                                           17    4312
XP_005275825                                                           17    4312
XP_003960932                                                           17    4312
XP_006710060                                                           17    4312
NP_001129474                                                           17    4312
NP_919299                                                              16    5631
XP_006719831                                                           16    5631
NP_001926                                                              16    7355
NP_001123488                                                           16    7355
NP_001257625                                                           16    7355
NP_001257624                                                           16    7355
NP_001123489                                                           16    7355
NP_060757                                                              16    7355
NP_001170                                                              16    7355
NP_001121904                                                           16    7355
NP_055803                                                              16    7355
NP_001276051                                                           16    7355
NP_001106189                                                           16    7355
NP_001106188                                                           16    7355
NP_008970                                                              16    7355
NP_001264154                                                           16    7355
NP_066024                                                              16    7355
XP_006720074                                                           16    7355
XP_005267344                                                           16    7355
XP_006717604                                                           16    7355
XP_006717603                                                           16    7355
XP_005263062                                                           16    7355
XP_005263061                                                           16    7355
XP_005263060                                                           16    7355
XP_005263059                                                           16    7355
XP_006714283                                                           16    7355
XP_005263056                                                           16    7355
XP_006714282                                                           16    7355
XP_006714281                                                           16    7355
XP_005263054                                                           16    7355
XP_006714061                                                           16    7355
XP_005248132                                                           16    7355
XP_005248131                                                           16    7355
XP_005248130                                                           16    7355
XP_005248129                                                           16    7355
XP_006714060                                                           16    7355
XP_005248128                                                           16    7355
XP_005248127                                                           16    7355
XP_005248126                                                           16    7355
XP_005248125                                                           16    7355
XP_005248120                                                           16    7355
XP_006714059                                                           16    7355
XP_005248119                                                           16    7355
XP_005248118                                                           16    7355
XP_005248117                                                           16    7355
XP_005248116                                                           16    7355
XP_005248115                                                           16    7355
XP_005248114                                                           16    7355
XP_005246428                                                           16    7355
NP_115495                                                              15    9605
NP_001137420                                                           15    9605
NP_116133                                                              15    9605
NP_002800                                                              15    9605
NP_003974                                                              15    9605
NP_001070253                                                           15    9605
NP_078988                                                              15    9605
XP_005272299                                                           15    9605
XP_005249511                                                           15    9605
NP_001968                                                              15    9605
>NP_006501
          Length = 513

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   YFSLSYS 7
           YFSLSYS
Sbjct: 473 YFSLSYS 479
>NP_115758
          Length = 612

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LS+SR
Sbjct: 351 YFGLSFSR 358
>NP_006149
          Length = 543

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFSLSYSRK 9
          Y+S SY R+
Sbjct: 9  YYSTSYKRR 17
>NP_002604
          Length = 556

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 156 YFGLSYAK 163
>NP_001248745
          Length = 454

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 156 YFGLSYAK 163
>XP_005255413
          Length = 529

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 129 YFGLSYAK 136
>XP_005275825
          Length = 218

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 129 YFGLSYAK 136
>XP_003960932
          Length = 396

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 129 YFGLSYAK 136
>XP_006710060
          Length = 425

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           YF LSY++
Sbjct: 129 YFGLSYAK 136
>NP_001129474
          Length = 380

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   YFSLSYSR 8
           YF L YSR
Sbjct: 295 YFHLHYSR 302
>NP_919299
          Length = 498

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YFSLSYSR 8
           +FS++YSR
Sbjct: 116 HFSVTYSR 123
>XP_006719831
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   YFSLSYSR 8
           +FS++YSR
Sbjct: 97  HFSVTYSR 104
>NP_001926
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   YFSLSYSRK 9
           Y+S+S+S++
Sbjct: 456 YYSVSFSKE 464
>NP_001123488
          Length = 389

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>NP_001257625
          Length = 816

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y+S SYS+
Sbjct: 324 YYSTSYSQ 331
>NP_001257624
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y+S SYS+
Sbjct: 324 YYSTSYSQ 331
>NP_001123489
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>NP_060757
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y+S SYS+
Sbjct: 324 YYSTSYSQ 331
>NP_001170
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>NP_001121904
          Length = 162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FSLSYSR 8
          FSLS+SR
Sbjct: 76 FSLSWSR 82
>NP_055803
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001276051
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001106189
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_001106188
          Length = 1057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>NP_008970
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSLSYS 7
           FSLSYS
Sbjct: 512 FSLSYS 517
>NP_001264154
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FSLSYSR 8
          FSLS+SR
Sbjct: 77 FSLSWSR 83
>NP_066024
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FSLSYSR 8
          FSLS+SR
Sbjct: 76 FSLSWSR 82
>XP_006720074
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSLSYS 7
           FSLSYS
Sbjct: 389 FSLSYS 394
>XP_005267344
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   FSLSYS 7
           FSLSYS
Sbjct: 512 FSLSYS 517
>XP_006717604
          Length = 820

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y+S SYS+
Sbjct: 324 YYSTSYSQ 331
>XP_006717603
          Length = 846

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y+S SYS+
Sbjct: 324 YYSTSYSQ 331
>XP_005263062
          Length = 353

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_005263061
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_005263060
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_005263059
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_006714283
          Length = 368

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_005263056
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_006714282
          Length = 379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_006714281
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_005263054
          Length = 400

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YFSLSYSRK 9
           +F+L+YS K
Sbjct: 182 HFTLAYSAK 190
>XP_006714061
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248132
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248131
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248130
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248129
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_006714060
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248128
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248127
          Length = 1322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248126
          Length = 1359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248125
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248120
          Length = 1549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_006714059
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248119
          Length = 1601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248118
          Length = 1602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248117
          Length = 1626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248116
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248115
          Length = 1629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005248114
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   SLSYSRK 9
           SL YSRK
Sbjct: 116 SLDYSRK 122
>XP_005246428
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   YFSLSYSRK 9
           Y+S+S+S++
Sbjct: 455 YYSVSFSKE 463
>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFSLSYSR 8
           Y SLS++R
Sbjct: 536 YLSLSFTR 543
>NP_001137420
          Length = 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YFSLSY 6
           +FSLSY
Sbjct: 214 FFSLSY 219
>NP_116133
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YFSLSY 6
           +FSLSY
Sbjct: 196 FFSLSY 201
>NP_002800
          Length = 534

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 411 SLSYSR 416
>NP_003974
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YFSLSY 6
           YFS SY
Sbjct: 392 YFSFSY 397
>NP_001070253
          Length = 515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   YFSLSY 6
           YFS SY
Sbjct: 392 YFSFSY 397
>NP_078988
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   FSLSYSR 8
           FS+SY R
Sbjct: 681 FSISYDR 687
>XP_005272299
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 159 SLSYSR 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 187 SLSYSR 192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 243 SLSYSR 248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 336 SLSYSR 341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 392 SLSYSR 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 448 SLSYSR 453

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   SLSYSR 8
           SLSYSR
Sbjct: 466 SLSYSR 471
>XP_005249511
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   YFSLSY 6
           +FSLSY
Sbjct: 196 FFSLSY 201
>NP_001968
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YFSLSYS 7
           YF+++YS
Sbjct: 336 YFAMNYS 342
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.131    0.367 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 517,121
Number of extensions: 994
Number of successful extensions: 75
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package