Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003290                                                              21     229
NP_002368                                                              18    1935
NP_000432                                                              17    4312
XP_005274039                                                           17    4312
XP_006716088                                                           17    4312
XP_006716087                                                           17    4312
XP_005250482                                                           17    4312
NP_955369                                                              17    4312
NP_000103                                                              16    5631
NP_078858                                                              16    5631
NP_001278232                                                           16    5631
NP_001278214                                                           16    5631
NP_068506                                                              16    5631
NP_071325                                                              16    5631
NP_998778                                                              16    5631
NP_602297                                                              16    5631
XP_006717556                                                           16    5631
XP_005252630                                                           16    5631
XP_005252629                                                           16    5631
XP_005252628                                                           16    5631
XP_005252627                                                           16    5631
XP_005252626                                                           16    5631
XP_005252624                                                           16    5631
XP_005252623                                                           16    5631
XP_005252622                                                           16    5631
XP_006717555                                                           16    5631
XP_005252621                                                           16    5631
XP_006713921                                                           16    5631
XP_006713920                                                           16    5631
XP_006713919                                                           16    5631
NP_061974                                                              16    7355
NP_002416                                                              16    7355
NP_599025                                                              16    7355
NP_001035544                                                           16    7355
NP_001268662                                                           16    7355
NP_075062                                                              16    7355
NP_001268661                                                           16    7355
NP_602298                                                              16    7355
NP_003633                                                              15    9605
NP_002413                                                              15    9605
NP_001273501                                                           15    9605
NP_001121700                                                           15    9605
NP_775897                                                              15    9605
NP_001276953                                                           15    9605
NP_714912                                                              15    9605
NP_001276952                                                           15    9605
NP_005526                                                              15    9605
NP_001159821                                                           15    9605
NP_001159820                                                           15    9605
NP_001159819                                                           15    9605
NP_055586                                                              15    9605
NP_001193962                                                           15    9605
NP_001193963                                                           15    9605
XP_006722804                                                           15    9605
XP_006721897                                                           15    9605
XP_006721896                                                           15    9605
XP_006712871                                                           15    9605
>NP_003290
          Length = 803

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   YFIAGSSRK 9
           YF+AGSSRK
Sbjct: 539 YFMAGSSRK 547
>NP_002368
          Length = 325

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YFIAGSSRK 9
           YF  GSS+K
Sbjct: 280 YFFVGSSKK 288
>NP_000432
          Length = 780

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YFI G+SR
Sbjct: 127 YFIFGTSR 134
>XP_005274039
          Length = 174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   YFIAGSS 7
           YF+AG+S
Sbjct: 94  YFVAGAS 100
>XP_006716088
          Length = 423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YFI G+SR
Sbjct: 127 YFIFGTSR 134
>XP_006716087
          Length = 780

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YFI G+SR
Sbjct: 127 YFIFGTSR 134
>XP_005250482
          Length = 780

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YFI G+SR
Sbjct: 127 YFIFGTSR 134
>NP_955369
          Length = 219

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  YFIAGSS 7
          YF+AG+S
Sbjct: 64 YFVAGAS 70
>NP_000103
          Length = 739

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 151 YFLLGTSR 158
>NP_078858
          Length = 4981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YFIAGSSRK 9
            Y I G+SRK
Sbjct: 3335 YLIFGNSRK 3343
>NP_001278232
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YFIAGSSRK 9
            Y I G+SRK
Sbjct: 3337 YLIFGNSRK 3345
>NP_001278214
          Length = 4982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    YFIAGSSRK 9
            Y I G+SRK
Sbjct: 3337 YLIFGNSRK 3345
>NP_068506
          Length = 2214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 642 YFSPGESRK 650
>NP_071325
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>NP_998778
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>NP_602297
          Length = 224

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>XP_006717556
          Length = 2024

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 410 YFSPGESRK 418
>XP_005252630
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 642 YFSPGESRK 650
>XP_005252629
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 642 YFSPGESRK 650
>XP_005252628
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 642 YFSPGESRK 650
>XP_005252627
          Length = 2256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 642 YFSPGESRK 650
>XP_005252626
          Length = 2260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 720 YFSPGESRK 728
>XP_005252624
          Length = 2292

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 720 YFSPGESRK 728
>XP_005252623
          Length = 2302

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 720 YFSPGESRK 728
>XP_005252622
          Length = 2308

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 720 YFSPGESRK 728
>XP_006717555
          Length = 2328

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 714 YFSPGESRK 722
>XP_005252621
          Length = 2334

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YFIAGSSRK 9
           YF  G SRK
Sbjct: 720 YFSPGESRK 728
>XP_006713921
          Length = 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>XP_006713920
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>XP_006713919
          Length = 701

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLMGTSR 119
>NP_061974
          Length = 188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  YFIAGSS 7
          YFIAG++
Sbjct: 48 YFIAGAA 54
>NP_002416
          Length = 476

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF +GSS+
Sbjct: 447 YFFSGSSQ 454
>NP_599025
          Length = 758

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 133 YFLFGTSR 140
>NP_001035544
          Length = 738

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 112 YFLFGTSR 119
>NP_001268662
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 133 YFLFGTSR 140
>NP_075062
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 133 YFLFGTSR 140
>NP_001268661
          Length = 723

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 133 YFLFGTSR 140
>NP_602298
          Length = 740

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   YFIAGSSR 8
           YF+ G+SR
Sbjct: 133 YFLFGTSR 140
>NP_003633
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  YFIAGS 6
          Y+IAGS
Sbjct: 77 YYIAGS 82
>NP_002413
          Length = 477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   YFIAGSSR 8
           YF  GSS+
Sbjct: 448 YFFTGSSQ 455
>NP_001273501
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YFIAGSS 7
           Y+++GSS
Sbjct: 311 YYVSGSS 317
>NP_001121700
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   AGSSRK 9
           AGSSRK
Sbjct: 569 AGSSRK 574
>NP_775897
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>NP_001276953
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YFIAGSSRK 9
           YF AGS+ +
Sbjct: 128 YFAAGSATR 136
>NP_714912
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFIAGSSRK 9
          YF AGS+ +
Sbjct: 88 YFAAGSATR 96
>NP_001276952
          Length = 660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFIAGSSRK 9
          YF AGS+ +
Sbjct: 88 YFAAGSATR 96
>NP_005526
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFIAGSSRK 9
          YF AGS+ +
Sbjct: 88 YFAAGSATR 96
>NP_001159821
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>NP_001159820
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>NP_001159819
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>NP_055586
          Length = 1001

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YFIAGSS 7
           Y+++GSS
Sbjct: 311 YYVSGSS 317
>NP_001193962
          Length = 1000

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YFIAGSS 7
           Y+++GSS
Sbjct: 311 YYVSGSS 317
>NP_001193963
          Length = 901

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1   YFIAGSS 7
           Y+++GSS
Sbjct: 311 YYVSGSS 317
>XP_006722804
          Length = 674

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  YFIAGSSRK 9
          YF AGS+ +
Sbjct: 88 YFAAGSATR 96
>XP_006721897
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>XP_006721896
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  YFIAGSSR 8
          YF  G+SR
Sbjct: 91 YFFLGTSR 98
>XP_006712871
          Length = 413

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  YFIAGS 6
          Y+IAGS
Sbjct: 71 YYIAGS 76
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.136    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 435,299
Number of extensions: 607
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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