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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              19     869
XP_005266703                                                           19     869
NP_000913                                                              17    2528
XP_005253029                                                           17    2528
NP_037506                                                              17    3301
NP_001155901                                                           17    3301
NP_065974                                                              17    3301
NP_001272478                                                           17    3301
XP_006712721                                                           17    3301
XP_006712720                                                           17    3301
XP_006712719                                                           17    3301
XP_005246770                                                           17    3301
XP_005246768                                                           17    3301
XP_005246769                                                           17    3301
XP_005250198                                                           17    4312
NP_660311                                                              17    4312
NP_001243506                                                           16    7355
NP_006004                                                              16    7355
NP_009153                                                              16    7355
NP_001017926                                                           16    7355
NP_001139281                                                           16    7355
NP_001074214                                                           16    7355
NP_001074213                                                           16    7355
NP_001070654                                                           16    7355
NP_079005                                                              16    7355
NP_001337                                                              16    7355
XP_006723449                                                           16    7355
NP_542784                                                              16    7355
NP_958357                                                              15    9605
NP_076919                                                              15    9605
XP_005258203                                                           15    9605
XP_005258202                                                           15    9605
XP_005258201                                                           15    9605
XP_005271318                                                           15    9605
XP_005271317                                                           15    9605
XP_005271314                                                           15    9605

>NP_443179
          Length = 2170

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   YEQSNSEAN 9
           YEQS SEAN
Sbjct: 739 YEQSISEAN 747



>XP_005266703
          Length = 1501

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  YEQSNSEAN 9
          YEQS SEAN
Sbjct: 70 YEQSISEAN 78



>NP_000913
          Length = 1112

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YEQ + EAN
Sbjct: 960 YEQGDEEAN 968



>XP_005253029
          Length = 1029

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YEQ + EAN
Sbjct: 877 YEQGDEEAN 885



>NP_037506
          Length = 868

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           +QSN+EAN
Sbjct: 640 KQSNNEAN 647



>NP_001155901
          Length = 873

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           +QSN+EAN
Sbjct: 645 KQSNNEAN 652



>NP_065974
          Length = 2354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>NP_001272478
          Length = 2352

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 485 YESSSSETN 493



>XP_006712721
          Length = 1206

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_006712720
          Length = 1991

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_006712719
          Length = 2354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_005246770
          Length = 2354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_005246768
          Length = 2354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_005246769
          Length = 2354

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           YE S+SE N
Sbjct: 487 YESSSSETN 495



>XP_005250198
          Length = 183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2  EQSNSEAN 9
          E+SNSEA+
Sbjct: 92 EESNSEAS 99



>NP_660311
          Length = 244

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           E+SNSEA+
Sbjct: 153 EESNSEAS 160



>NP_001243506
          Length = 216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  YEQSNSEA 8
          YEQ +SEA
Sbjct: 57 YEQLSSEA 64



>NP_006004
          Length = 214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  YEQSNSEA 8
          YEQ +SEA
Sbjct: 57 YEQLSSEA 64



>NP_009153
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           Y Q NS++N
Sbjct: 517 YNQRNSKSN 525



>NP_001017926
          Length = 873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YEQSNSEAN 9
           Y Q NS++N
Sbjct: 517 YNQRNSKSN 525



>NP_001139281
          Length = 2036

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EQSNSE 7
            EQSNSE
Sbjct: 1806 EQSNSE 1811



>NP_001074214
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SNSEAN 9
           SNSEAN
Sbjct: 96  SNSEAN 101



>NP_001074213
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SNSEAN 9
           SNSEAN
Sbjct: 96  SNSEAN 101



>NP_001070654
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EQSNSE 7
            EQSNSE
Sbjct: 1773 EQSNSE 1778



>NP_079005
          Length = 1995

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EQSNSE 7
            EQSNSE
Sbjct: 1765 EQSNSE 1770



>NP_001337
          Length = 791

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SNSEAN 9
           SNSEAN
Sbjct: 96  SNSEAN 101



>XP_006723449
          Length = 2003

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    EQSNSE 7
            EQSNSE
Sbjct: 1773 EQSNSE 1778



>NP_542784
          Length = 214

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  YEQSNSEA 8
          YEQ +SEA
Sbjct: 57 YEQLSSEA 64



>NP_958357
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           E+SN++AN
Sbjct: 728 EKSNAKAN 735



>NP_076919
          Length = 233

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  YEQSNS 6
          Y+QSNS
Sbjct: 58 YQQSNS 63



>XP_005258203
          Length = 721

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  YEQSNSEAN 9
          + +SNSEA+
Sbjct: 82 FSRSNSEAS 90



>XP_005258202
          Length = 740

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  YEQSNSEAN 9
          + +SNSEA+
Sbjct: 82 FSRSNSEAS 90



>XP_005258201
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  YEQSNSEAN 9
          + +SNSEA+
Sbjct: 82 FSRSNSEAS 90



>XP_005271318
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           E+SN++AN
Sbjct: 728 EKSNAKAN 735



>XP_005271317
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           E+SN++AN
Sbjct: 728 EKSNAKAN 735



>XP_005271314
          Length = 1368

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   EQSNSEAN 9
           E+SN++AN
Sbjct: 728 EKSNAKAN 735



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.274   0.0946    0.221 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 419,078
Number of extensions: 837
Number of successful extensions: 36
Number of sequences better than 10000.0: 36
Number of HSP's gapped: 36
Number of HSP's successfully gapped: 36
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.5 bits)
S2: 28 (15.4 bits)