Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     299
NP_001075109                                                           20     299
NP_689914                                                              18    1935
NP_001038188                                                           17    2528
NP_004375                                                              17    2528
NP_001257501                                                           17    2528
NP_001257502                                                           17    2528
NP_001257503                                                           17    2528
NP_001026982                                                           17    2528
NP_001310                                                              17    2528
NP_001919                                                              17    2528
XP_005259559                                                           17    2528
XP_005259558                                                           17    2528
XP_005259557                                                           17    2528
XP_005259556                                                           17    2528
XP_005259555                                                           17    2528
XP_005271953                                                           17    2528
XP_005271952                                                           17    2528
XP_005271951                                                           17    2528
XP_005271950                                                           17    2528
XP_005271949                                                           17    2528
XP_005271948                                                           17    2528
NP_001165907                                                           17    4312
NP_002628                                                              17    4312
NP_001116142                                                           17    4312
NP_000312                                                              17    4312
NP_001091738                                                           17    4312
NP_002303                                                              17    4312
NP_996820                                                              17    4312
XP_006724724                                                           17    4312
XP_006720015                                                           17    4312
XP_005254115                                                           17    4312
XP_005254113                                                           17    4312
XP_005254114                                                           17    4312
XP_006720014                                                           17    4312
XP_006720013                                                           17    4312
NP_001274691                                                           16    5631
NP_001274690                                                           16    5631
NP_004204                                                              16    5631
NP_002824                                                              16    5631
XP_005255050                                                           16    5631
XP_005255048                                                           16    5631
XP_005255046                                                           16    5631
NP_006368                                                              15    9605
XP_006716779                                                           15    9605
>NP_008835
          Length = 4128

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YDVLRAIFT 9
            YDVLR IFT
Sbjct: 2936 YDVLRGIFT 2944
>NP_001075109
          Length = 4097

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YDVLRAIFT 9
            YDVLR IFT
Sbjct: 2936 YDVLRGIFT 2944
>NP_689914
          Length = 5058

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    YDVLRAIFT 9
            YDVL+ +FT
Sbjct: 4605 YDVLKWVFT 4613
>NP_001038188
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 301 YDYLRKLFT 309
>NP_004375
          Length = 447

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 301 YDYLRKLFT 309
>NP_001257501
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 302 YDYLRKLFT 310
>NP_001257502
          Length = 348

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 226 YDYLRKLFT 234
>NP_001257503
          Length = 311

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 189 YDYLRKLFT 197
>NP_001026982
          Length = 423

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 301 YDYLRKLFT 309
>NP_001310
          Length = 415

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 305 YDYLRKLFT 313
>NP_001919
          Length = 253

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YDVLRAI 7
           YDVLRA+
Sbjct: 95  YDVLRAV 101
>XP_005259559
          Length = 367

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 257 YDYLRKLFT 265
>XP_005259558
          Length = 392

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 257 YDYLRKLFT 265
>XP_005259557
          Length = 440

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 305 YDYLRKLFT 313
>XP_005259556
          Length = 445

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 335 YDYLRKLFT 343
>XP_005259555
          Length = 445

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 335 YDYLRKLFT 343
>XP_005271953
          Length = 416

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 302 YDYLRKLFT 310
>XP_005271952
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 302 YDYLRKLFT 310
>XP_005271951
          Length = 447

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 301 YDYLRKLFT 309
>XP_005271950
          Length = 448

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 302 YDYLRKLFT 310
>XP_005271949
          Length = 455

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 301 YDYLRKLFT 309
>XP_005271948
          Length = 456

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD LR +FT
Sbjct: 302 YDYLRKLFT 310
>NP_001165907
          Length = 1151

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD+ + IFT
Sbjct: 511 YDIRKTIFT 519
>NP_002628
          Length = 1223

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD+ + IFT
Sbjct: 511 YDIRKTIFT 519
>NP_001116142
          Length = 1210

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD+ + IFT
Sbjct: 511 YDIRKTIFT 519
>NP_000312
          Length = 928

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           YDVL A+F+
Sbjct: 155 YDVLFALFS 163
>NP_001091738
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>NP_002303
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>NP_996820
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_006724724
          Length = 1164

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   YDVLRAIFT 9
           YD+ + IFT
Sbjct: 511 YDIRKTIFT 519
>XP_006720015
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_005254115
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_005254113
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_005254114
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_006720014
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>XP_006720013
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           Y++L +IFT
Sbjct: 386 YEILSSIFT 394
>NP_001274691
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 569 VLRALFT 575
>NP_001274690
          Length = 483

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 403 VLRALFT 409
>NP_004204
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 569 VLRALFT 575
>NP_002824
          Length = 593

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  YDVLRAI 7
          +DVLRAI
Sbjct: 56 FDVLRAI 62
>XP_005255050
          Length = 623

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 543 VLRALFT 549
>XP_005255048
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 569 VLRALFT 575
>XP_005255046
          Length = 649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VLRAIFT 9
           VLRA+FT
Sbjct: 569 VLRALFT 575
>NP_006368
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   YDVLRAIFT 9
           ++V+R +FT
Sbjct: 566 FEVIRDVFT 574
>XP_006716779
          Length = 2399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    YDVLRAIFT 9
            ++V+R +FT
Sbjct: 1374 FEVIRDVFT 1382
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.343    0.154    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,389
Number of extensions: 617
Number of successful extensions: 45
Number of sequences better than 10000.0: 45
Number of HSP's gapped: 45
Number of HSP's successfully gapped: 45
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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