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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_443179                                                              18    1482
XP_005266703                                                           18    1482
NP_009117                                                              16    5631
XP_005260322                                                           16    5631
XP_005260321                                                           16    5631
XP_005260320                                                           16    5631
XP_006723758                                                           16    5631
XP_006723757                                                           16    5631
XP_006723756                                                           16    5631
XP_006723755                                                           16    5631
XP_006723754                                                           16    5631
XP_006723753                                                           16    5631
XP_005260319                                                           16    5631
NP_002449                                                              16    7355
NP_803879                                                              16    7355
NP_803881                                                              16    7355
NP_001258992                                                           16    7355
NP_110428                                                              16    7355
NP_001229291                                                           16    7355
NP_001258991                                                           16    7355
NP_001092270                                                           16    7355
NP_001258990                                                           16    7355
XP_006724671                                                           16    7355
XP_006724670                                                           16    7355
NP_003283                                                              15    9605
NP_001104517                                                           15    9605
NP_001104516                                                           15    9605
NP_001104515                                                           15    9605
NP_597732                                                              15    9605
XP_006722741                                                           15    9605
XP_006722740                                                           15    9605
XP_006722739                                                           15    9605
XP_006722738                                                           15    9605
XP_006722737                                                           15    9605
XP_005259567                                                           15    9605
XP_005245528                                                           15    9605
NP_003905                                                              15    9605

>NP_443179
          Length = 2170

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YAAEAQLLE 9
            YAAEAQ LE
Sbjct: 1995 YAAEAQPLE 2003



>XP_005266703
          Length = 1501

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    YAAEAQLLE 9
            YAAEAQ LE
Sbjct: 1326 YAAEAQPLE 1334



>NP_009117
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_005260322
          Length = 1810

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   AAEAQLLE 9
           A EAQLLE
Sbjct: 487 AQEAQLLE 494



>XP_005260321
          Length = 2365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1042 AQEAQLLE 1049



>XP_005260320
          Length = 2370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_006723758
          Length = 2386

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1063 AQEAQLLE 1070



>XP_006723757
          Length = 2404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_006723756
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_006723755
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_006723754
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_006723753
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>XP_005260319
          Length = 2442

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    AAEAQLLE 9
            A EAQLLE
Sbjct: 1119 AQEAQLLE 1126



>NP_002449
          Length = 5762

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    YAAEAQLLE 9
            Y+AEAQ ++
Sbjct: 5691 YSAEAQAMQ 5699



>NP_803879
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_803881
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_001258992
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_110428
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_001229291
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_001258991
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_001092270
          Length = 739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_001258990
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>XP_006724671
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>XP_006724670
          Length = 741

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   YAAEAQ 6
           YAAEAQ
Sbjct: 152 YAAEAQ 157



>NP_003283
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AEAQLLE 9
            AE+QLLE
Sbjct: 1120 AESQLLE 1126



>NP_001104517
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YAAEAQLLE 9
           Y AE  LLE
Sbjct: 323 YVAELSLLE 331



>NP_001104516
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YAAEAQLLE 9
           Y AE  LLE
Sbjct: 323 YVAELSLLE 331



>NP_001104515
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YAAEAQLLE 9
           Y AE  LLE
Sbjct: 366 YVAELSLLE 374



>NP_597732
          Length = 1146

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1014 HAAEAQL 1020



>XP_006722741
          Length = 1117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   YAAEAQL 7
           +AAEAQL
Sbjct: 985 HAAEAQL 991



>XP_006722740
          Length = 1153

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1021 HAAEAQL 1027



>XP_006722739
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1049 HAAEAQL 1055



>XP_006722738
          Length = 1181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1049 HAAEAQL 1055



>XP_006722737
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1050 HAAEAQL 1056



>XP_005259567
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    YAAEAQL 7
            +AAEAQL
Sbjct: 1085 HAAEAQL 1091



>XP_005245528
          Length = 2439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    AEAQLLE 9
            AE+QLLE
Sbjct: 1196 AESQLLE 1202



>NP_003905
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   YAAEAQLLE 9
           Y AE  LLE
Sbjct: 367 YVAELSLLE 375



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.120    0.289 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 313,224
Number of extensions: 365
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)