Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_002430                                                              18    1482
NP_005679                                                              17    2528
NP_001018881                                                           17    2528
XP_005247116                                                           17    2528
XP_005247115                                                           17    2528
NP_001238774                                                           17    4312
NP_003295                                                              17    4312
XP_005273894                                                           17    4312
XP_005247796                                                           17    4312
XP_005247795                                                           17    4312
NP_878253                                                              17    4312
NP_008870                                                              16    7355
XP_005268078                                                           16    7355
XP_006714901                                                           16    7355
NP_001092878                                                           16    7355
NP_055426                                                              15    9605
NP_055137                                                              15    9605
XP_005248757                                                           15    9605
XP_006715468                                                           15    9605
XP_005248756                                                           15    9605
XP_006715467                                                           15    9605
NP_776257                                                              15    9605



>NP_002430
          Length = 1137

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   IFSLAKVA 9
           IFSLAKVA
Sbjct: 834 IFSLAKVA 841





>NP_005679
          Length = 1437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           W+ SLA+VA
Sbjct: 114 WLSSLARVA 122





>NP_001018881
          Length = 208

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           W+ SLA+VA
Sbjct: 114 WLSSLARVA 122





>XP_005247116
          Length = 1437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           W+ SLA+VA
Sbjct: 114 WLSSLARVA 122





>XP_005247115
          Length = 1437

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           W+ SLA+VA
Sbjct: 114 WLSSLARVA 122





>NP_001238774
          Length = 793

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           +IFSLA VA
Sbjct: 597 YIFSLAHVA 605





>NP_003295
          Length = 759

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           +IFSLA VA
Sbjct: 563 YIFSLAHVA 571





>XP_005273894
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WIFSLA 6
           W+FSLA
Sbjct: 432 WLFSLA 437





>XP_005247796
          Length = 661

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           +IFSLA VA
Sbjct: 465 YIFSLAHVA 473





>XP_005247795
          Length = 695

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WIFSLAKVA 9
           +IFSLA VA
Sbjct: 499 YIFSLAHVA 507





>NP_878253
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WIFSLA 6
           W+FSLA
Sbjct: 432 WLFSLA 437





>NP_008870
          Length = 1332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   WIFSLAKV 8
           W+ S+AK+
Sbjct: 727 WVESIAKI 734





>XP_005268078
          Length = 1272

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   WIFSLAKV 8
           W+ S+AK+
Sbjct: 667 WVESIAKI 674





>XP_006714901
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WIFSLAK 7
           W+ SLAK
Sbjct: 138 WLVSLAK 144





>NP_001092878
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WIFSLAK 7
           W+ SLAK
Sbjct: 138 WLVSLAK 144





>NP_055426
          Length = 5596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    WIFSLAK 7
            W++ LAK
Sbjct: 2538 WLYHLAK 2544





>NP_055137
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   WIFSLA 6
           W++SLA
Sbjct: 162 WLYSLA 167





>XP_005248757
          Length = 3591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WIFSLAK 7
           W++ LAK
Sbjct: 533 WLYHLAK 539





>XP_006715468
          Length = 3744

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WIFSLAK 7
           W++ LAK
Sbjct: 686 WLYHLAK 692





>XP_005248756
          Length = 3905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WIFSLAK 7
           W++ LAK
Sbjct: 847 WLYHLAK 853





>XP_006715467
          Length = 5550

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1    WIFSLAK 7
            W++ LAK
Sbjct: 2538 WLYHLAK 2544





>NP_776257
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   IFSLAKV 8
           IFSLAK+
Sbjct: 150 IFSLAKL 156





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.133    0.479 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 324,057
Number of extensions: 326
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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