Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_543144                                                              17    2528
NP_001078921                                                           17    3301
NP_006287                                                              17    3301
NP_001275767                                                           17    3301
NP_001275766                                                           17    3301
NP_001123952                                                           17    3301
NP_001123955                                                           17    3301
NP_001123953                                                           17    3301
NP_001123954                                                           17    3301
NP_056482                                                              17    3301
NP_001108479                                                           17    3301
NP_001108480                                                           17    3301
NP_001275926                                                           17    3301
NP_919258                                                              17    3301
NP_001076593                                                           17    3301
NP_001107013                                                           17    3301
XP_005272574                                                           17    3301
XP_006716914                                                           17    3301
XP_005262809                                                           17    3301
XP_006714144                                                           17    3301
XP_005262807                                                           17    3301
XP_005262806                                                           17    3301
XP_006712154                                                           17    3301
XP_006712153                                                           17    3301
XP_005264597                                                           17    3301
NP_001138668                                                           17    3301
NP_000247                                                              16    5631
NP_001269622                                                           16    5631
NP_001032852                                                           16    5631
NP_002012                                                              16    5631
NP_001269621                                                           16    5631
NP_001269623                                                           16    5631
XP_006718301                                                           16    5631
XP_005245095                                                           16    5631
XP_006711305                                                           16    5631
XP_005245094                                                           16    5631
XP_006711304                                                           16    5631
NP_795371                                                              16    7355
NP_870991                                                              15    9605
NP_065854                                                              15    9605
NP_001193923                                                           15    9605
NP_001193924                                                           15    9605
NP_002009                                                              15    9605
NP_000441                                                              15    9605
NP_001193925                                                           15    9605
NP_001018062                                                           15    9605
NP_001018060                                                           15    9605
NP_115655                                                              15    9605
NP_001243193                                                           15    9605
NP_001269813                                                           15    9605
NP_001269814                                                           15    9605
NP_612211                                                              15    9605
NP_001243194                                                           15    9605
XP_005256615                                                           15    9605
XP_005256613                                                           15    9605
XP_005256612                                                           15    9605
XP_005263210                                                           15    9605
XP_005248036                                                           15    9605
XP_005248035                                                           15    9605
XP_005248034                                                           15    9605
XP_005247886                                                           15    9605
XP_005247729                                                           15    9605
>NP_543144
          Length = 295

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WIFAKKIN 8
           W+FA+K N
Sbjct: 100 WVFARKGN 107
>NP_001078921
          Length = 1361

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1187 WIFSKK 1192
>NP_006287
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001275767
          Length = 396

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001275766
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001123952
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001123955
          Length = 396

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001123953
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001123954
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 6  WVLGKKIGS 14
>NP_056482
          Length = 1347

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1173 WIFSKK 1178
>NP_001108479
          Length = 528

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  IFAKKINS 9
          IFAK INS
Sbjct: 25 IFAKPINS 32
>NP_001108480
          Length = 528

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  IFAKKINS 9
          IFAK INS
Sbjct: 25 IFAKPINS 32
>NP_001275926
          Length = 528

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  IFAKKINS 9
          IFAK INS
Sbjct: 25 IFAKPINS 32
>NP_919258
          Length = 749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   IFAKKINS 9
           IFAK INS
Sbjct: 246 IFAKPINS 253
>NP_001076593
          Length = 1347

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1173 WIFSKK 1178
>NP_001107013
          Length = 1347

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1173 WIFSKK 1178
>XP_005272574
          Length = 1207

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1033 WIFSKK 1038
>XP_006716914
          Length = 848

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   WIFAKK 6
           WIF+KK
Sbjct: 674 WIFSKK 679
>XP_005262809
          Length = 546

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  IFAKKINS 9
          IFAK INS
Sbjct: 43 IFAKPINS 50
>XP_006714144
          Length = 749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   IFAKKINS 9
           IFAK INS
Sbjct: 246 IFAKPINS 253
>XP_005262807
          Length = 749

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   IFAKKINS 9
           IFAK INS
Sbjct: 246 IFAKPINS 253
>XP_005262806
          Length = 767

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   IFAKKINS 9
           IFAK INS
Sbjct: 264 IFAKPINS 271
>XP_006712154
          Length = 396

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>XP_006712153
          Length = 397

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>XP_005264597
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          W+  KKI S
Sbjct: 29 WVLGKKIGS 37
>NP_001138668
          Length = 1343

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    WIFAKK 6
            WIF+KK
Sbjct: 1169 WIFSKK 1174
>NP_000247
          Length = 1274

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WIFAKKI 7
           W+F KK+
Sbjct: 711 WVFDKKL 717
>NP_001269622
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 254 WLMERKINN 262
>NP_001032852
          Length = 1125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    WIFAKKINS 9
            W + K++NS
Sbjct: 1088 WYYDKQVNS 1096
>NP_002012
          Length = 532

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 254 WLMERKINN 262
>NP_001269621
          Length = 536

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 258 WLMERKINN 266
>NP_001269623
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 191 WLMERKINN 199
>XP_006718301
          Length = 1268

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WIFAKKI 7
           W+F KK+
Sbjct: 705 WVFDKKL 711
>XP_005245095
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 254 WLMERKINN 262
>XP_006711305
          Length = 418

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 254 WLMERKINN 262
>XP_005245094
          Length = 436

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 158 WLMERKINN 166
>XP_006711304
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           W+  +KIN+
Sbjct: 254 WLMERKINN 262
>NP_795371
          Length = 299

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  WIFAKKINS 9
          W+  KKI+S
Sbjct: 35 WVKRKKISS 43
>NP_870991
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 436 YIFQDKVNS 444
>NP_065854
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WIFAKKINS 9
           W F  ++NS
Sbjct: 346 WFFGPEMNS 354
>NP_001193923
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 429 YIFQDKVNS 437
>NP_001193924
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 429 YIFQDKVNS 437
>NP_002009
          Length = 1269

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 674 LFAEKIN 680
>NP_000441
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  WIFAKKINS 9
          WI  +K+N+
Sbjct: 71 WIGIRKVNN 79
>NP_001193925
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 419 YIFQDKVNS 427
>NP_001018062
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W F +K+N
Sbjct: 16 WQFERKLN 23
>NP_001018060
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W F +K+N
Sbjct: 16 WQFERKLN 23
>NP_115655
          Length = 1196

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          WI+   +NS
Sbjct: 91 WIYLSALNS 99
>NP_001243193
          Length = 1258

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 663 LFAEKIN 669
>NP_001269813
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W F +K+N
Sbjct: 16 WQFERKLN 23
>NP_001269814
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W F +K+N
Sbjct: 16 WQFERKLN 23
>NP_612211
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W F +K+N
Sbjct: 16 WQFERKLN 23
>NP_001243194
          Length = 1214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 619 LFAEKIN 625
>XP_005256615
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 673 LFAEKIN 679
>XP_005256613
          Length = 1295

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 673 LFAEKIN 679
>XP_005256612
          Length = 1296

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   IFAKKIN 8
           +FA+KIN
Sbjct: 674 LFAEKIN 680
>XP_005263210
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   WIFAKKINS 9
           W F  ++NS
Sbjct: 163 WFFGPEMNS 171
>XP_005248036
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 219 YIFQDKVNS 227
>XP_005248035
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 331 YIFQDKVNS 339
>XP_005248034
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WIFAKKINS 9
           +IF  K+NS
Sbjct: 436 YIFQDKVNS 444
>XP_005247886
          Length = 1127

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1  WIFAKKINS 9
          WI+   +NS
Sbjct: 91 WIYLSALNS 99
>XP_005247729
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 6/8 (75%)

Query: 1  WIFAKKIN 8
          W + K++N
Sbjct: 84 WAYKKRVN 91
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.133    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 400,878
Number of extensions: 661
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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