Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000779                                                              17    2528
NP_000268                                                              17    4312
NP_001010915                                                           17    4312
NP_653194                                                              17    4312
NP_001191354                                                           17    4312
XP_005268691                                                           17    4312
NP_060163                                                              17    4312
NP_001153068                                                           17    4312
NP_004384                                                              16    5631
NP_001171110                                                           16    5631
NP_001171113                                                           16    5631
NP_001171114                                                           16    5631
NP_001159400                                                           16    5631
NP_001171111                                                           16    5631
NP_001171112                                                           16    5631
NP_001171115                                                           16    5631
NP_001171107                                                           16    5631
NP_001171105                                                           16    5631
NP_001171106                                                           16    5631
NP_001171109                                                           16    5631
NP_001171108                                                           16    5631
NP_550440                                                              16    5631
NP_550438                                                              16    5631
XP_005264231                                                           16    5631
XP_005264230                                                           16    5631
NP_006436                                                              16    7355
NP_001026892                                                           16    7355
NP_055079                                                              16    7355
NP_001177728                                                           16    7355
NP_001177730                                                           16    7355
NP_066976                                                              16    7355
NP_919288                                                              16    7355
XP_005275674                                                           16    7355
XP_005275669                                                           16    7355
XP_005275543                                                           16    7355
XP_005275538                                                           16    7355
XP_005275370                                                           16    7355
XP_005275365                                                           16    7355
XP_005275248                                                           16    7355
XP_005275243                                                           16    7355
XP_005275113                                                           16    7355
XP_005275108                                                           16    7355
XP_005272958                                                           16    7355
XP_005272953                                                           16    7355
XP_006722503                                                           16    7355
XP_005249477                                                           16    7355
XP_005249472                                                           16    7355
XP_006714134                                                           16    7355
XP_005262758                                                           16    7355
XP_006712548                                                           16    7355
XP_005246130                                                           16    7355
NP_001207706                                                           15    9605
NP_510867                                                              15    9605
NP_001207707                                                           15    9605
NP_000380                                                              15    9605
NP_001001912                                                           15    9605
NP_055938                                                              15    9605
NP_938146                                                              15    9605
NP_005410                                                              15    9605
NP_079515                                                              15    9605
XP_005269168                                                           15    9605
XP_005269167                                                           15    9605
XP_006719635                                                           15    9605
XP_005269166                                                           15    9605
XP_005269165                                                           15    9605
XP_005251659                                                           15    9605
XP_005251658                                                           15    9605
XP_005251657                                                           15    9605
XP_005264777                                                           15    9605
XP_001716411                                                           15    9605
>NP_000779
          Length = 260

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W FTF T
Sbjct: 92 WSFTFQT 98
>NP_000268
          Length = 452

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG  F TL+
Sbjct: 187 WGTVFKTLK 195
>NP_001010915
          Length = 232

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  WGFTFMTLR 9
          W FT MT+R
Sbjct: 33 WIFTNMTVR 41
>NP_653194
          Length = 183

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WGFTFM 6
           WG TFM
Sbjct: 141 WGATFM 146
>NP_001191354
          Length = 1640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           W F F T+R
Sbjct: 428 WNFPFGTIR 436
>XP_005268691
          Length = 181

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WGFTFM 6
           WG TFM
Sbjct: 139 WGATFM 144
>NP_060163
          Length = 503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           W F F T+R
Sbjct: 428 WNFPFGTIR 436
>NP_001153068
          Length = 281

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           W F F T+R
Sbjct: 206 WNFPFGTIR 214
>NP_004384
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171110
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171113
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171114
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001159400
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171111
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171112
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171115
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171107
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171105
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171106
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171109
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_001171108
          Length = 895

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          WG TF+ L
Sbjct: 14 WGRTFLLL 21
>NP_550440
          Length = 189

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   WGFTFMT 7
           W +TF T
Sbjct: 106 WSYTFQT 112
>NP_550438
          Length = 277

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1   WGFTFMT 7
           W +TF T
Sbjct: 106 WSYTFQT 112
>XP_005264231
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W +TF T
Sbjct: 9  WSYTFQT 15
>XP_005264230
          Length = 180

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W +TF T
Sbjct: 9  WSYTFQT 15
>NP_006436
          Length = 2335

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1    WGFTFMTLR 9
            W + FM +R
Sbjct: 2279 WNYNFMGVR 2287
>NP_001026892
          Length = 409

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>NP_055079
          Length = 970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG+   TLR
Sbjct: 580 WGYQNRTLR 588
>NP_001177728
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG+   TLR
Sbjct: 548 WGYQNRTLR 556
>NP_001177730
          Length = 929

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG+   TLR
Sbjct: 539 WGYQNRTLR 547
>NP_066976
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WGFTFMTL 8
           +GF F+TL
Sbjct: 609 FGFIFLTL 616
>NP_919288
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG +  TLR
Sbjct: 648 WGVSVRTLR 656
>XP_005275674
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275669
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275543
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275538
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275370
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275365
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275248
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275243
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275113
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005275108
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005272958
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005272953
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_006722503
          Length = 772

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   WGFTFMTL 8
           +GF F+TL
Sbjct: 609 FGFIFLTL 616
>XP_005249477
          Length = 288

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_005249472
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1  WGFTFMTL 8
          W F F+T+
Sbjct: 5  WPFCFLTI 12
>XP_006714134
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG+   TLR
Sbjct: 533 WGYQNRTLR 541
>XP_005262758
          Length = 936

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG+   TLR
Sbjct: 546 WGYQNRTLR 554
>XP_006712548
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG +  TLR
Sbjct: 280 WGVSVRTLR 288
>XP_005246130
          Length = 637

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WGFTFMTLR 9
           WG +  TLR
Sbjct: 280 WGVSVRTLR 288
>NP_001207706
          Length = 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W F F+T
Sbjct: 49 WNFDFVT 55
>NP_510867
          Length = 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W F F+T
Sbjct: 49 WNFDFVT 55
>NP_001207707
          Length = 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W F F+T
Sbjct: 49 WNFDFVT 55
>NP_000380
          Length = 164

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 5/7 (71%)

Query: 1  WGFTFMT 7
          W F F+T
Sbjct: 49 WNFDFVT 55
>NP_001001912
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GFTFMTLR 9
           G TF+T+R
Sbjct: 158 GQTFLTIR 165
>NP_055938
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1  WGFTFMTLR 9
          W  T  TLR
Sbjct: 21 WNLTVSTLR 29
>NP_938146
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 394 WDFGYLTL 401
>NP_005410
          Length = 851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 398 WDFGYLTL 405
>NP_079515
          Length = 273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   WGFTFMTLR 9
           W + ++TL+
Sbjct: 110 WDYKYLTLK 118
>XP_005269168
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 466 WDFGYLTL 473
>XP_005269167
          Length = 532

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 466 WDFGYLTL 473
>XP_006719635
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 466 WDFGYLTL 473
>XP_005269166
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 462 WDFGYLTL 469
>XP_005269165
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   WGFTFMTL 8
           W F ++TL
Sbjct: 466 WDFGYLTL 473
>XP_005251659
          Length = 280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   WGFTFMTLR 9
           W + ++TL+
Sbjct: 110 WDYKYLTLK 118
>XP_005251658
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   WGFTFMTLR 9
           W + ++TL+
Sbjct: 110 WDYKYLTLK 118
>XP_005251657
          Length = 283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1   WGFTFMTLR 9
           W + ++TL+
Sbjct: 110 WDYKYLTLK 118
>XP_005264777
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 5/9 (55%)

Query: 1  WGFTFMTLR 9
          W  T  TLR
Sbjct: 21 WNLTVSTLR 29
>XP_001716411
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1  WGFTFMT 7
          +GFTF++
Sbjct: 93 YGFTFLS 99
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.344    0.147    0.622 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,536
Number of extensions: 574
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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