Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004645                                                              19     869
NP_001034680                                                           19     869
NP_001034679                                                           19     869
XP_005272733                                                           19     869
XP_005272732                                                           19     869
NP_004295                                                              18    1135
NP_055847                                                              17    4312
NP_001009921                                                           17    4312
XP_005266355                                                           17    4312
XP_005266354                                                           17    4312
XP_005266353                                                           17    4312
XP_005266352                                                           17    4312
XP_006713619                                                           17    4312
XP_005247308                                                           17    4312
XP_005245794                                                           17    4312
XP_005245795                                                           17    4312
XP_005245793                                                           17    4312
NP_056118                                                              17    4312
NP_001832                                                              17    4312
NP_001265667                                                           16    5631
NP_057677                                                              16    5631
NP_001265668                                                           16    5631
NP_001077059                                                           16    5631
XP_005264440                                                           16    5631
XP_006712099                                                           16    5631
XP_005264439                                                           16    5631
XP_005264438                                                           16    5631
NP_060197                                                              16    5631
NP_004510                                                              16    7355
NP_001191753                                                           16    7355
NP_848612                                                              16    7355
NP_115612                                                              16    7355
NP_001034859                                                           16    7355
NP_001027902                                                           16    7355
NP_067082                                                              16    7355
XP_006725381                                                           16    7355
XP_006725380                                                           16    7355
XP_005257295                                                           16    7355
XP_006721894                                                           16    7355
XP_006716617                                                           16    7355
XP_006711018                                                           16    7355
XP_006711017                                                           16    7355
XP_005246067                                                           16    7355
XP_006711016                                                           16    7355
XP_005246066                                                           16    7355
XP_006711015                                                           16    7355
XP_006711014                                                           16    7355
XP_006711013                                                           16    7355
XP_006711012                                                           16    7355
NP_001129710                                                           16    7355
NP_000024                                                              15    9605
NP_775864                                                              15    9605
NP_057209                                                              15    9605
NP_001092688                                                           15    9605
NP_001035536                                                           15    9605
NP_065073                                                              15    9605
XP_006722960                                                           15    9605
XP_006722959                                                           15    9605
XP_006722958                                                           15    9605
XP_006722957                                                           15    9605
XP_006722956                                                           15    9605
XP_006722955                                                           15    9605
XP_006722954                                                           15    9605
XP_006722953                                                           15    9605
XP_006722952                                                           15    9605
XP_006722951                                                           15    9605
XP_006722950                                                           15    9605
XP_006715582                                                           15    9605
XP_005248373                                                           15    9605
XP_005248371                                                           15    9605
XP_005248370                                                           15    9605
XP_005262682                                                           15    9605
NP_078828                                                              15    9605
>NP_004645
          Length = 2555

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFILLELMA 9
           WF LLEL+A
Sbjct: 168 WFPLLELLA 176
>NP_001034680
          Length = 2554

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFILLELMA 9
           WF LLEL+A
Sbjct: 167 WFPLLELLA 175
>NP_001034679
          Length = 2570

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFILLELMA 9
           WF LLEL+A
Sbjct: 167 WFPLLELLA 175
>XP_005272733
          Length = 2559

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFILLELMA 9
           WF LLEL+A
Sbjct: 167 WFPLLELLA 175
>XP_005272732
          Length = 2575

 Score = 18.9 bits (37), Expect =   869
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   WFILLELMA 9
           WF LLEL+A
Sbjct: 167 WFPLLELLA 175
>NP_004295
          Length = 1620

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    FILLELMA 9
            FILLELMA
Sbjct: 1193 FILLELMA 1200
>NP_055847
          Length = 1447

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFILLELMA 9
            WF+L  LMA
Sbjct: 1022 WFVLEILMA 1030
>NP_001009921
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    WFILLELM 8
            WF LLE M
Sbjct: 1143 WFPLLEAM 1150
>XP_005266355
          Length = 1448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFILLELMA 9
            WF+L  LMA
Sbjct: 1022 WFVLEILMA 1030
>XP_005266354
          Length = 1411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFILLELMA 9
            WF+L  LMA
Sbjct: 1022 WFVLEILMA 1030
>XP_005266353
          Length = 1445

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFILLELMA 9
            WF+L  LMA
Sbjct: 1022 WFVLEILMA 1030
>XP_005266352
          Length = 1446

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    WFILLELMA 9
            WF+L  LMA
Sbjct: 1022 WFVLEILMA 1030
>XP_006713619
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   WFILLELM 8
           WF LLE M
Sbjct: 571 WFPLLEAM 578
>XP_005247308
          Length = 1428

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    WFILLELM 8
            WF LLE M
Sbjct: 1143 WFPLLEAM 1150
>XP_005245794
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           WF +L LMA
Sbjct: 258 WFPVLALMA 266
>XP_005245795
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           WF +L LMA
Sbjct: 258 WFPVLALMA 266
>XP_005245793
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           WF +L LMA
Sbjct: 258 WFPVLALMA 266
>NP_056118
          Length = 1426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    WFILLELM 8
            WF LLE M
Sbjct: 1141 WFPLLEAM 1148
>NP_001832
          Length = 360

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           WF +L LMA
Sbjct: 258 WFPVLALMA 266
>NP_001265667
          Length = 449

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF LLE+
Sbjct: 398 WFALLEV 404
>NP_057677
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF LLE+
Sbjct: 418 WFALLEV 424
>NP_001265668
          Length = 297

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF LLE+
Sbjct: 246 WFALLEV 252
>NP_001077059
          Length = 644

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 584 WHLLLEALA 592
>XP_005264440
          Length = 352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 292 WHLLLEALA 300
>XP_006712099
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 648 WHLLLEALA 656
>XP_005264439
          Length = 715

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 655 WHLLLEALA 663
>XP_005264438
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 693 WHLLLEALA 701
>NP_060197
          Length = 689

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   WFILLELMA 9
           W +LLE +A
Sbjct: 629 WHLLLEALA 637
>NP_004510
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   WFILLELMA 9
           W +LLE  A
Sbjct: 155 WLLLLETFA 163
>NP_001191753
          Length = 752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WFILLELMA 9
          W +LLE  A
Sbjct: 35 WLLLLETFA 43
>NP_848612
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>NP_115612
          Length = 1035

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>NP_001034859
          Length = 453

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 288 WFALLE 293
>NP_001027902
          Length = 485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>NP_067082
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   WFILLELM 8
           W++ L+LM
Sbjct: 467 WYLSLQLM 474
>XP_006725381
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006725380
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_005257295
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006721894
          Length = 504

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  FILLELM 8
          FILLEL+
Sbjct: 78 FILLELL 84
>XP_006716617
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  WFILLELMA 9
          W +LLE  A
Sbjct: 46 WLLLLETFA 54
>XP_006711018
          Length = 969

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711017
          Length = 981

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  WFILLEL 7
          WF+ LEL
Sbjct: 40 WFLNLEL 46
>XP_005246067
          Length = 982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711016
          Length = 982

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_005246066
          Length = 983

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711015
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711014
          Length = 1046

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711013
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>XP_006711012
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           WF+ LEL
Sbjct: 107 WFLNLEL 113
>NP_001129710
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 151 WFALLE 156
>NP_000024
          Length = 745

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/6 (50%), Positives = 6/6 (100%)

Query: 1   WFILLE 6
           W+++LE
Sbjct: 326 WYVMLE 331
>NP_775864
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  WFILLELMA 9
          W + LEL+A
Sbjct: 37 WTLYLELVA 45
>NP_057209
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 1   WFILLE 6
           W++LLE
Sbjct: 285 WYMLLE 290
>NP_001092688
          Length = 1159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W +LLE+
Sbjct: 432 WLLLLEI 438
>NP_001035536
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 353 WFSLLE 358
>NP_065073
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    WFILLE 6
            W ILLE
Sbjct: 1454 WIILLE 1459
>XP_006722960
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 207 WWYLLEL 213
>XP_006722959
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 181 WWYLLEL 187
>XP_006722958
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722957
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722956
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722955
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722954
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722953
          Length = 400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 187 WWYLLEL 193
>XP_006722952
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 192 WWYLLEL 198
>XP_006722951
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 201 WWYLLEL 207
>XP_006722950
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 207 WWYLLEL 213
>XP_006715582
          Length = 2106

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1    WFILLE 6
            W ILLE
Sbjct: 1383 WIILLE 1388
>XP_005248373
          Length = 637

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 353 WFSLLE 358
>XP_005248371
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 353 WFSLLE 358
>XP_005248370
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 1   WFILLE 6
           WF LLE
Sbjct: 353 WFSLLE 358
>XP_005262682
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W +LLE+
Sbjct: 423 WLLLLEI 429
>NP_078828
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   WFILLEL 7
           W+ LLEL
Sbjct: 181 WWYLLEL 187
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.150    0.561 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 433,981
Number of extensions: 599
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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