Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_002259                                                              17    2528
NP_001243089                                                           17    2528
NP_079273                                                              17    2528
XP_006721017                                                           17    2528
XP_006721016                                                           17    2528
NP_001186480                                                           17    3301
NP_001186552                                                           17    3301
NP_001186481                                                           17    3301
NP_071377                                                              17    3301
NP_005671                                                              17    3301
XP_005265433                                                           17    3301
XP_005265432                                                           17    3301
XP_005265431                                                           17    3301
NP_115921                                                              16    5631
NP_036581                                                              16    5631
XP_005267222                                                           16    5631
NP_057262                                                              16    5631
NP_055752                                                              16    7355
NP_001230124                                                           16    7355
NP_001139129                                                           16    7355
NP_002258                                                              16    7355
NP_001139130                                                           16    7355
NP_002876                                                              16    7355
XP_006717783                                                           16    7355
XP_006717782                                                           16    7355
XP_006710870                                                           16    7355
XP_005246013                                                           16    7355
XP_006710869                                                           16    7355
XP_005246012                                                           16    7355
XP_005246011                                                           16    7355
XP_006710868                                                           16    7355
XP_006710867                                                           16    7355
NP_579875                                                              15    9605
NP_002368                                                              15    9605
NP_758847                                                              15    9605
NP_001138238                                                           15    9605
NP_000112                                                              15    9605
NP_003306                                                              15    9605
NP_000102                                                              15    9605
NP_001075019                                                           15    9605
NP_006257                                                              15    9605
NP_001035827                                                           15    9605
NP_001258705                                                           15    9605
NP_001258704                                                           15    9605
NP_001258703                                                           15    9605
XP_006724836                                                           15    9605
XP_005262507                                                           15    9605
XP_006724835                                                           15    9605
XP_006724834                                                           15    9605
XP_006724833                                                           15    9605
XP_006724832                                                           15    9605
XP_006724831                                                           15    9605
XP_006724830                                                           15    9605
XP_005262504                                                           15    9605
XP_006722360                                                           15    9605
XP_006722117                                                           15    9605
XP_006722116                                                           15    9605
XP_006722115                                                           15    9605
XP_006722114                                                           15    9605
XP_006722113                                                           15    9605
XP_006715936                                                           15    9605
NP_001270                                                              15    9605
NP_001004461                                                           15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           VYS SYELI
Sbjct: 646 VYSFSYELI 654
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           VYS SYELI
Sbjct: 646 VYSFSYELI 654
>NP_002259
          Length = 521

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           +Y L+YE+I
Sbjct: 473 IYKLAYEII 481
>NP_001243089
          Length = 543

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VYSLSYEL 8
           +YS++YEL
Sbjct: 329 IYSINYEL 336
>NP_079273
          Length = 682

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VYSLSYEL 8
           +YS++YEL
Sbjct: 329 IYSINYEL 336
>XP_006721017
          Length = 366

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VYSLSYEL 8
           +YS++YEL
Sbjct: 329 IYSINYEL 336
>XP_006721016
          Length = 682

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VYSLSYEL 8
           +YS++YEL
Sbjct: 329 IYSINYEL 336
>NP_001186480
          Length = 248

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 179 YSLSYDL 185
>NP_001186552
          Length = 251

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 182 YSLSYDL 188
>NP_001186481
          Length = 238

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 169 YSLSYDL 175
>NP_071377
          Length = 238

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 169 YSLSYDL 175
>NP_005671
          Length = 588

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLSY+ I
Sbjct: 535 YSLSYQFI 542
>XP_005265433
          Length = 164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 95  YSLSYDL 101
>XP_005265432
          Length = 164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 95  YSLSYDL 101
>XP_005265431
          Length = 238

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSLSY+L
Sbjct: 169 YSLSYDL 175
>NP_115921
          Length = 1894

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VYSLSYE 7
            VYS SYE
Sbjct: 1692 VYSASYE 1698
>NP_036581
          Length = 339

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYSLSYEL 8
           +YSLSY +
Sbjct: 177 IYSLSYPM 184
>XP_005267222
          Length = 1819

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    VYSLSYE 7
            VYS SYE
Sbjct: 1617 VYSASYE 1623
>NP_057262
          Length = 235

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  VYSLSY 6
          VYSLSY
Sbjct: 10 VYSLSY 15
>NP_055752
          Length = 1132

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSL+Y+L
Sbjct: 178 YSLTYDL 184
>NP_001230124
          Length = 219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSL+Y+L
Sbjct: 178 YSLTYDL 184
>NP_001139129
          Length = 681

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 113 VFSLKYDVI 121
>NP_002258
          Length = 521

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           +Y L++E+I
Sbjct: 473 IYKLAFEII 481
>NP_001139130
          Length = 727

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 177 VFSLKYDVI 185
>NP_002876
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 113 VFSLKYDVI 121
>XP_006717783
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSL+Y+L
Sbjct: 178 YSLTYDL 184
>XP_006717782
          Length = 1089

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YSLSYEL 8
           YSL+Y+L
Sbjct: 135 YSLTYDL 141
>XP_006710870
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 144 VFSLKYDVI 152
>XP_005246013
          Length = 800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 250 VFSLKYDVI 258
>XP_006710869
          Length = 812

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 177 VFSLKYDVI 185
>XP_005246012
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 250 VFSLKYDVI 258
>XP_005246011
          Length = 826

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 250 VFSLKYDVI 258
>XP_006710868
          Length = 877

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 250 VFSLKYDVI 258
>XP_006710867
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYSLSYELI 9
           V+SL Y++I
Sbjct: 250 VFSLKYDVI 258
>NP_579875
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YSLSYELI 9
          YSLS EL+
Sbjct: 20 YSLSRELL 27
>NP_002368
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  YSLSYEL 8
          Y+L YEL
Sbjct: 91 YALDYEL 97
>NP_758847
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YSLSYELI 9
          YSLS EL+
Sbjct: 20 YSLSRELL 27
>NP_001138238
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 216 YKLAYEL 222
>NP_000112
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  YSLSYEL 8
          YS SY+L
Sbjct: 77 YSFSYQL 83
>NP_003306
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 272 YKLAYEL 278
>NP_000102
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VYSLSYE 7
           VYSL Y+
Sbjct: 360 VYSLKYD 366
>NP_001075019
          Length = 1593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>NP_006257
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLS EL+
Sbjct: 525 YSLSRELL 532
>NP_001035827
          Length = 859

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLS EL+
Sbjct: 470 YSLSRELL 477
>NP_001258705
          Length = 902

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLS EL+
Sbjct: 513 YSLSRELL 520
>NP_001258704
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLS EL+
Sbjct: 524 YSLSRELL 531
>NP_001258703
          Length = 885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YSLSYELI 9
           YSLS EL+
Sbjct: 496 YSLSRELL 503
>XP_006724836
          Length = 1582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_005262507
          Length = 1594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724835
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724834
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724833
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724832
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724831
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006724830
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_005262504
          Length = 1642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  VYSLSYELI 9
          +Y LSY +I
Sbjct: 49 LYELSYHVI 57
>XP_006722360
          Length = 120

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1  VYSLSYEL 8
          +YS+SY++
Sbjct: 55 MYSVSYDI 62
>XP_006722117
          Length = 401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 160 YKLAYEL 166
>XP_006722116
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 216 YKLAYEL 222
>XP_006722115
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 216 YKLAYEL 222
>XP_006722114
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 216 YKLAYEL 222
>XP_006722113
          Length = 513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YSLSYEL 8
           Y L+YEL
Sbjct: 272 YKLAYEL 278
>XP_006715936
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VYSLSYE 7
           VYSL Y+
Sbjct: 360 VYSLKYD 366
>NP_001270
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VYSLSYEL 8
           +YS+SY++
Sbjct: 154 MYSVSYDI 161
>NP_001004461
          Length = 314

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYSLSYELI 9
           V SLSY L+
Sbjct: 273 VMSLSYSLL 281
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.140    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 567,195
Number of extensions: 1045
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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