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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001269346                                                           18    1482
NP_001035915                                                           18    1482
NP_689564                                                              18    1482
NP_001257578                                                           18    1482
NP_001257577                                                           18    1482
XP_006721514                                                           18    1482
XP_005256514                                                           18    1482
NP_443187                                                              17    4312
NP_056483                                                              16    5631
NP_001273622                                                           16    5631
NP_001273621                                                           16    5631
XP_005250917                                                           16    5631
XP_006716604                                                           16    5631
XP_005250916                                                           16    5631
XP_006716603                                                           16    5631
XP_005250915                                                           16    5631
XP_005250914                                                           16    5631
XP_005250913                                                           16    5631
NP_853514                                                              16    7355
NP_690607                                                              16    7355
NP_004972                                                              16    7355
NP_001124427                                                           15    9605
NP_001273681                                                           15    9605
NP_004506                                                              15    9605
NP_076982                                                              15    9605
NP_001254738                                                           15    9605
NP_059134                                                              15    9605
NP_001269619                                                           15    9605
NP_001269617                                                           15    9605
XP_005261058                                                           15    9605
XP_005261057                                                           15    9605
XP_005261060                                                           15    9605
XP_006724084                                                           15    9605
XP_005261056                                                           15    9605
XP_005252255                                                           15    9605
XP_005252253                                                           15    9605
XP_005252252                                                           15    9605
XP_005252250                                                           15    9605

>NP_001269346
          Length = 566

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1  VYLSSEILT 9
          +Y+SSEI+T
Sbjct: 55 IYISSEIVT 63



>NP_001035915
          Length = 596

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>NP_689564
          Length = 612

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>NP_001257578
          Length = 560

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>NP_001257577
          Length = 569

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>XP_006721514
          Length = 596

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>XP_005256514
          Length = 633

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   VYLSSEILT 9
           +Y+SSEI+T
Sbjct: 111 IYISSEIVT 119



>NP_443187
          Length = 710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VYL SEIL
Sbjct: 150 VYLPSEIL 157



>NP_056483
          Length = 1264

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>NP_001273622
          Length = 1083

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 287 YLSAEILS 294



>NP_001273621
          Length = 1252

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 456 YLSAEILS 463



>XP_005250917
          Length = 824

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>XP_006716604
          Length = 1045

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>XP_005250916
          Length = 1099

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>XP_006716603
          Length = 1168

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 372 YLSAEILS 379



>XP_005250915
          Length = 1210

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>XP_005250914
          Length = 1211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>XP_005250913
          Length = 1211

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   YLSSEILT 9
           YLS+EIL+
Sbjct: 468 YLSAEILS 475



>NP_853514
          Length = 1732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           +YLS E+L
Sbjct: 330 IYLSEELL 337



>NP_690607
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YLSSEIL 8
           YL+SEIL
Sbjct: 307 YLASEIL 313



>NP_004972
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   YLSSEIL 8
           YL+SEIL
Sbjct: 307 YLASEIL 313



>NP_001124427
          Length = 1173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYLSSEILT 9
          V+L +E+LT
Sbjct: 89 VFLDNELLT 97



>NP_001273681
          Length = 416

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 272 VYVSREIL 279



>NP_004506
          Length = 390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YLSSEILT 9
           YL+SEI T
Sbjct: 338 YLASEIST 345



>NP_076982
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 80 YLSSEI 85



>NP_001254738
          Length = 352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   YLSSEILT 9
           YL+SEI T
Sbjct: 300 YLASEIST 307



>NP_059134
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 296 VYVSREIL 303



>NP_001269619
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 12 YLSSEI 17



>NP_001269617
          Length = 853

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 80 YLSSEI 85



>XP_005261058
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 296 VYVSREIL 303



>XP_005261057
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 296 VYVSREIL 303



>XP_005261060
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 296 VYVSREIL 303



>XP_006724084
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 296 VYVSREIL 303



>XP_005261056
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYLSSEIL 8
           VY+S EIL
Sbjct: 313 VYVSREIL 320



>XP_005252255
          Length = 786

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 12 YLSSEI 17



>XP_005252253
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 80 YLSSEI 85



>XP_005252252
          Length = 816

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 80 YLSSEI 85



>XP_005252250
          Length = 824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  YLSSEI 7
          YLSSEI
Sbjct: 80 YLSSEI 85



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.130    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 411,190
Number of extensions: 835
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)