Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003473                                                              19     665
NP_733751                                                              19     665
XP_006719679                                                           19     665
XP_005269219                                                           19     665
XP_006719678                                                           19     665
XP_006719677                                                           19     665
XP_006716142                                                           19     665
XP_005250088                                                           19     665
XP_006716141                                                           19     665
XP_005250085                                                           19     665
XP_006716140                                                           19     665
XP_005250084                                                           19     665
XP_005250083                                                           19     665
XP_005250082                                                           19     665
NP_006675                                                              16    5631
NP_066303                                                              16    5631
NP_001160096                                                           16    5631
NP_001188480                                                           16    5631
NP_001188479                                                           16    5631
XP_006711196                                                           16    5631
XP_006711195                                                           16    5631
XP_006711194                                                           16    5631
XP_006711193                                                           16    5631
XP_006711192                                                           16    5631
XP_006711191                                                           16    5631
NP_997191                                                              16    7355
NP_001152956                                                           16    7355
XP_006711682                                                           16    7355
>NP_003473
          Length = 5537

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 5399 VYLARSRIQ 5407
>NP_733751
          Length = 4911

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4773 VYLARSRIQ 4781
>XP_006719679
          Length = 5536

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 5398 VYLARSRIQ 5406
>XP_005269219
          Length = 5537

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 5399 VYLARSRIQ 5407
>XP_006719678
          Length = 5539

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 5401 VYLARSRIQ 5409
>XP_006719677
          Length = 5540

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 5402 VYLARSRIQ 5410
>XP_006716142
          Length = 4927

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4789 VYLARSRIQ 4797
>XP_005250088
          Length = 4928

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4790 VYLARSRIQ 4798
>XP_006716141
          Length = 4959

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4821 VYLARSRIQ 4829
>XP_005250085
          Length = 4979

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4841 VYLARSRIQ 4849
>XP_006716140
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4844 VYLARSRIQ 4852
>XP_005250084
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4844 VYLARSRIQ 4852
>XP_005250083
          Length = 4982

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4844 VYLARSRIQ 4852
>XP_005250082
          Length = 4983

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VYLAQSRIQ 9
            VYLA+SRIQ
Sbjct: 4845 VYLARSRIQ 4853
>NP_006675
          Length = 331

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 229 VYVPQSRVE 237
>NP_066303
          Length = 330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 228 VYVPQSRVE 236
>NP_001160096
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 167 VYVPQSRVE 175
>NP_001188480
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 475 VYVPQSRVE 483
>NP_001188479
          Length = 578

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 476 VYVPQSRVE 484
>XP_006711196
          Length = 519

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 417 VYVPQSRVE 425
>XP_006711195
          Length = 523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 421 VYVPQSRVE 429
>XP_006711194
          Length = 533

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 431 VYVPQSRVE 439
>XP_006711193
          Length = 568

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 466 VYVPQSRVE 474
>XP_006711192
          Length = 570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 468 VYVPQSRVE 476
>XP_006711191
          Length = 573

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYLAQSRIQ 9
           VY+ QSR++
Sbjct: 471 VYVPQSRVE 479
>NP_997191
          Length = 1888

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LAQSRIQ 9
            LAQSR+Q
Sbjct: 1874 LAQSRLQ 1880
>NP_001152956
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LAQSRIQ 9
            LAQSR+Q
Sbjct: 1722 LAQSRLQ 1728
>XP_006711682
          Length = 1739

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3    LAQSRIQ 9
            LAQSR+Q
Sbjct: 1725 LAQSRLQ 1731
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.329    0.133    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 294,728
Number of extensions: 269
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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