Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_058640                                                              17    3301
NP_008927                                                              16    5631
NP_599030                                                              16    5631
NP_058641                                                              16    5631
XP_005257062                                                           16    5631
NP_057197                                                              16    7355
NP_055486                                                              16    7355
NP_001229725                                                           16    7355
NP_001229724                                                           16    7355
NP_001077422                                                           16    7355
NP_071348                                                              16    7355
NP_055484                                                              16    7355
XP_005256735                                                           16    7355
XP_005256734                                                           16    7355
XP_006721606                                                           16    7355
XP_006721605                                                           16    7355
XP_006721604                                                           16    7355
XP_005256733                                                           16    7355
XP_005256320                                                           16    7355
XP_005249622                                                           16    7355
XP_005249621                                                           16    7355
XP_006712132                                                           16    7355
XP_006712130                                                           16    7355
XP_006712129                                                           16    7355
XP_006712128                                                           16    7355
XP_006712127                                                           16    7355
XP_006712126                                                           16    7355
XP_006712125                                                           16    7355
XP_006712124                                                           16    7355
NP_065908                                                              16    7355
NP_068813                                                              15    9605
NP_056998                                                              15    9605
NP_848622                                                              15    9605
NP_001008487                                                           15    9605
NP_001008486                                                           15    9605
NP_001008485                                                           15    9605
NP_065185                                                              15    9605
NP_002214                                                              15    9605
NP_060306                                                              15    9605
NP_036265                                                              15    9605
NP_001276962                                                           15    9605
NP_079113                                                              15    9605
NP_001157947                                                           15    9605
XP_006720757                                                           15    9605
XP_006720756                                                           15    9605
XP_006719127                                                           15    9605
XP_006715729                                                           15    9605
XP_006715728                                                           15    9605
XP_006715727                                                           15    9605
XP_006715726                                                           15    9605
XP_005247622                                                           15    9605
XP_005247621                                                           15    9605
XP_006713744                                                           15    9605
XP_005247620                                                           15    9605
XP_005247619                                                           15    9605
XP_005247618                                                           15    9605
XP_005247617                                                           15    9605
XP_005247616                                                           15    9605
XP_005245413                                                           15    9605
XP_005245412                                                           15    9605
NP_872352                                                              15    9605
NP_795362                                                              15    9605
NP_795363                                                              15    9605
>NP_058640
          Length = 299

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VYFKILYL 8
           VYF ILY+
Sbjct: 233 VYFLILYI 240
>NP_008927
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           V F+I+Y+L
Sbjct: 394 VVFRIIYML 402
>NP_599030
          Length = 190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VYFKIL 6
           VYFKIL
Sbjct: 122 VYFKIL 127
>NP_058641
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VYFKILYLL 9
          V+F I+Y+L
Sbjct: 8  VFFMIIYVL 16
>XP_005257062
          Length = 202

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   VYFKIL 6
           VYFKIL
Sbjct: 122 VYFKIL 127
>NP_057197
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>NP_055486
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YFKILYLL 9
           Y++ LYLL
Sbjct: 207 YYRSLYLL 214
>NP_001229725
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VYFKILYL 8
           +YF++L+L
Sbjct: 338 LYFQVLFL 345
>NP_001229724
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VYFKILYL 8
           +YF++L+L
Sbjct: 338 LYFQVLFL 345
>NP_001077422
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1458 VYIDILFLL 1466
>NP_071348
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1458 VYIDILFLL 1466
>NP_055484
          Length = 819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VYFKILYL 8
           +YF++L+L
Sbjct: 461 LYFQVLFL 468
>XP_005256735
          Length = 548

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>XP_005256734
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>XP_006721606
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>XP_006721605
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>XP_006721604
          Length = 733

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 469 YFEILFL 475
>XP_005256733
          Length = 763

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   YFKILYL 8
           YF+IL+L
Sbjct: 468 YFEILFL 474
>XP_005256320
          Length = 819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   VYFKILYL 8
           +YF++L+L
Sbjct: 461 LYFQVLFL 468
>XP_005249622
          Length = 1021

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YFKILYLL 9
           Y++ LYLL
Sbjct: 207 YYRSLYLL 214
>XP_005249621
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YFKILYLL 9
           Y++ LYLL
Sbjct: 182 YYRSLYLL 189
>XP_006712132
          Length = 1136

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VYFKILYLL 9
           VY  IL+LL
Sbjct: 641 VYIDILFLL 649
>XP_006712130
          Length = 1831

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1336 VYIDILFLL 1344
>XP_006712129
          Length = 1832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1337 VYIDILFLL 1345
>XP_006712128
          Length = 1879

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1384 VYIDILFLL 1392
>XP_006712127
          Length = 1909

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1458 VYIDILFLL 1466
>XP_006712126
          Length = 1913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1418 VYIDILFLL 1426
>XP_006712125
          Length = 1952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1457 VYIDILFLL 1465
>XP_006712124
          Length = 1953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VY  IL+LL
Sbjct: 1458 VYIDILFLL 1466
>NP_065908
          Length = 973

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           +YF+ LY+L
Sbjct: 188 LYFRPLYVL 196
>NP_068813
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   VYFKILYLL 9
           V FK  YLL
Sbjct: 380 VRFKFFYLL 388
>NP_056998
          Length = 958

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   YFKILYL 8
           YF ++YL
Sbjct: 180 YFPVIYL 186
>NP_848622
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YFKILYLL 9
           YF  LY+L
Sbjct: 646 YFMFLYVL 653
>NP_001008487
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 362 IFFYIIYLV 370
>NP_001008486
          Length = 471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 352 IFFYIIYLV 360
>NP_001008485
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>NP_065185
          Length = 1223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VYF IL+ +
Sbjct: 1063 VYFAILFAM 1071
>NP_002214
          Length = 2701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2    YFKILY 7
            +FK+LY
Sbjct: 1806 FFKVLY 1811
>NP_060306
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>NP_036265
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KILYLL 9
          KILYLL
Sbjct: 50 KILYLL 55
>NP_001276962
          Length = 726

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  KILYLL 9
          KILYLL
Sbjct: 50 KILYLL 55
>NP_079113
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            +YF IL+ +
Sbjct: 1031 IYFSILFTM 1039
>NP_001157947
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 271 IFFYIIYLV 279
>XP_006720757
          Length = 1008

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   VYFKILYLL 9
           +YF IL+ +
Sbjct: 847 IYFSILFTM 855
>XP_006720756
          Length = 1229

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            +YF IL+ +
Sbjct: 1068 IYFSILFTM 1076
>XP_006719127
          Length = 1865

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2    YFKILY 7
            +FK+LY
Sbjct: 1806 FFKVLY 1811
>XP_006715729
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VYFKILYL 8
          V+F +LY+
Sbjct: 12 VFFSVLYV 19
>XP_006715728
          Length = 228

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VYFKILYL 8
          V+F +LY+
Sbjct: 12 VFFSVLYV 19
>XP_006715727
          Length = 240

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VYFKILYL 8
          V+F +LY+
Sbjct: 12 VFFSVLYV 19
>XP_006715726
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VYFKILYL 8
          V+F +LY+
Sbjct: 12 VFFSVLYV 19
>XP_005247622
          Length = 481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 362 IFFYIIYLV 370
>XP_005247621
          Length = 502

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 403 IFFYIIYLV 411
>XP_006713744
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>XP_005247620
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>XP_005247619
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>XP_005247618
          Length = 507

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 388 IFFYIIYLV 396
>XP_005247617
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 403 IFFYIIYLV 411
>XP_005247616
          Length = 522

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   VYFKILYLL 9
           ++F I+YL+
Sbjct: 403 IFFYIIYLV 411
>XP_005245413
          Length = 1190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VYF IL+ +
Sbjct: 1030 VYFAILFAM 1038
>XP_005245412
          Length = 1209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    VYFKILYLL 9
            VYF IL+ +
Sbjct: 1049 VYFAILFAM 1057
>NP_872352
          Length = 236

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1  VYFKILYL 8
          V+F +LY+
Sbjct: 12 VFFSVLYV 19
>NP_795362
          Length = 338

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YFKILYL 8
           YF ILY+
Sbjct: 266 YFLILYI 272
>NP_795363
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   YFKILYL 8
           YF ILY+
Sbjct: 251 YFLILYI 257
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.352    0.172    0.514 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 462,290
Number of extensions: 846
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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