Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1935
NP_001035957                                                           18    1935
XP_006721991                                                           18    1935
XP_006721990                                                           18    1935
XP_006721989                                                           18    1935
XP_005258041                                                           18    1935
XP_006721988                                                           18    1935
XP_006721987                                                           18    1935
XP_006721986                                                           18    1935
XP_005258040                                                           18    1935
XP_006721985                                                           18    1935
NP_001036216                                                           17    2528
NP_005853                                                              17    2528
NP_001036214                                                           17    2528
NP_006594                                                              17    2528
NP_001036215                                                           17    2528
NP_001269347                                                           17    2528
XP_006724791                                                           17    2528
XP_005262418                                                           17    2528
XP_005262417                                                           17    2528
XP_005262416                                                           17    2528
XP_005262415                                                           17    2528
XP_006724790                                                           17    2528
XP_005262414                                                           17    2528
XP_006713534                                                           17    2528
NP_001269645                                                           16    5631
NP_036579                                                              16    5631
NP_001269646                                                           16    5631
NP_001269647                                                           16    5631
NP_115964                                                              16    5631
NP_001073922                                                           16    5631
XP_006725304                                                           16    5631
XP_006725303                                                           16    5631
XP_005255699                                                           16    5631
XP_005255698                                                           16    5631
XP_005250173                                                           16    5631
NP_003840                                                              16    7355
NP_001005168                                                           16    7355
NP_001005167                                                           16    7355
NP_004906                                                              15    9605
NP_997511                                                              15    9605
NP_058198                                                              15    9605
NP_997512                                                              15    9605
NP_997510                                                              15    9605
NP_997057                                                              15    9605
NP_689854                                                              15    9605
NP_079357                                                              15    9605
XP_006719336                                                           15    9605
XP_006719335                                                           15    9605
>NP_000258
          Length = 2818

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1076 VVSLLAGL 1083
>NP_001035957
          Length = 2839

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1076 VVSLLAGL 1083
>XP_006721991
          Length = 1632

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>XP_006721990
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>XP_006721989
          Length = 2823

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>XP_005258041
          Length = 2836

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1076 VVSLLAGL 1083
>XP_006721988
          Length = 2846

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>XP_006721987
          Length = 2849

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>XP_006721986
          Length = 2854

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1073 VVSLLAGL 1080
>XP_005258040
          Length = 2857

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1076 VVSLLAGL 1083
>XP_006721985
          Length = 2867

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    VVSLLAGL 8
            VVSLLAGL
Sbjct: 1086 VVSLLAGL 1093
>NP_001036216
          Length = 1231

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>NP_005853
          Length = 1258

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 203 VISLLTGLS 211
>NP_001036214
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>NP_006594
          Length = 1231

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>NP_001036215
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>NP_001269347
          Length = 1231

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_006724791
          Length = 1199

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 131 VISLLTGLS 139
>XP_005262418
          Length = 1231

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_005262417
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_005262416
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_005262415
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_006724790
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_005262414
          Length = 1268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 200 VISLLTGLS 208
>XP_006713534
          Length = 1222

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           V+SLL GLS
Sbjct: 203 VISLLTGLS 211
>NP_001269645
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           ++SLL GLS
Sbjct: 216 LISLLTGLS 224
>NP_036579
          Length = 1225

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           ++SLL GLS
Sbjct: 216 LISLLTGLS 224
>NP_001269646
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           ++SLL GLS
Sbjct: 216 LISLLTGLS 224
>NP_001269647
          Length = 1167

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           ++SLL GLS
Sbjct: 158 LISLLTGLS 166
>NP_115964
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VVSLLAG 7
           VVSLLAG
Sbjct: 430 VVSLLAG 436
>NP_001073922
          Length = 2190

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    SLLAGLS 9
            SLLAGLS
Sbjct: 2000 SLLAGLS 2006
>XP_006725304
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VVSLLAG 7
           VVSLLAG
Sbjct: 430 VVSLLAG 436
>XP_006725303
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VVSLLAG 7
           VVSLLAG
Sbjct: 430 VVSLLAG 436
>XP_005255699
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VVSLLAG 7
           VVSLLAG
Sbjct: 430 VVSLLAG 436
>XP_005255698
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VVSLLAG 7
           VVSLLAG
Sbjct: 430 VVSLLAG 436
>XP_005250173
          Length = 1222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           ++SLL GLS
Sbjct: 216 LISLLTGLS 224
>NP_003840
          Length = 346

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVS +AGL+
Sbjct: 282 VVSFIAGLT 290
>NP_001005168
          Length = 317

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VVSLLAGLS 9
           ++SL+AG++
Sbjct: 146 IISLIAGIA 154
>NP_001005167
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   VVSLLAGLS 9
           ++SL+AG++
Sbjct: 142 IISLIAGIA 150
>NP_004906
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 255 VVSLMKGLA 263
>NP_997511
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 233 VVSLMKGLA 241
>NP_058198
          Length = 666

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 255 VVSLMKGLA 263
>NP_997512
          Length = 663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 252 VVSLMKGLA 260
>NP_997510
          Length = 668

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 257 VVSLMKGLA 265
>NP_997057
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVSLLAGLS 9
           VVSL+ GL+
Sbjct: 266 VVSLMKGLA 274
>NP_689854
          Length = 1835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VVSLLAGL 8
           V+SLL+GL
Sbjct: 162 VLSLLSGL 169
>NP_079357
          Length = 1898

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    VVSLLAGLS 9
            ++SL +GLS
Sbjct: 1414 IISLTSGLS 1422
>XP_006719336
          Length = 1779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VVSLLAGL 8
           V+SLL+GL
Sbjct: 162 VLSLLSGL 169
>XP_006719335
          Length = 1793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   VVSLLAGL 8
           V+SLL+GL
Sbjct: 162 VLSLLSGL 169
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.136    0.321 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 365,321
Number of extensions: 572
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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