Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000213                                                              18    1135
NP_001087241                                                           18    1135
XP_006714101                                                           18    1135
XP_005265799                                                           18    1135
XP_005265798                                                           18    1135
XP_005265797                                                           18    1135
NP_001058                                                              16    5631
NP_001013725                                                           16    5631
NP_001229416                                                           16    5631
NP_001229417                                                           16    5631
NP_055852                                                              16    5631
XP_005257689                                                           16    5631
XP_005254449                                                           16    5631
XP_005269712                                                           16    5631
XP_006717788                                                           16    5631
XP_005269710                                                           16    5631
XP_005269709                                                           16    5631
XP_005269708                                                           16    5631
XP_005269706                                                           16    5631
XP_005269705                                                           16    5631
NP_001012660                                                           16    5631
NP_001277189                                                           16    7355
NP_055968                                                              16    7355
NP_001006642                                                           16    7355
NP_077008                                                              16    7355
NP_001252543                                                           16    7355
NP_001006643                                                           16    7355
NP_852111                                                              16    7355
NP_000136                                                              16    7355
NP_443133                                                              16    7355
NP_001277188                                                           16    7355
NP_055400                                                              16    7355
NP_060733                                                              16    7355
XP_006722947                                                           16    7355
XP_005251746                                                           16    7355
XP_006717012                                                           16    7355
XP_006717011                                                           16    7355
XP_005251745                                                           16    7355
XP_005248759                                                           16    7355
XP_006715489                                                           16    7355
XP_005248758                                                           16    7355
XP_005246562                                                           16    7355
XP_005246561                                                           16    7355
XP_006712103                                                           16    7355
XP_006712102                                                           16    7355
NP_000142                                                              15    9605
NP_001138508                                                           15    9605
NP_001157912                                                           15    9605
NP_031383                                                              15    9605
NP_004924                                                              15    9605
NP_001136026                                                           15    9605
NP_848613                                                              15    9605
NP_001129507                                                           15    9605
NP_689967                                                              15    9605
NP_060192                                                              15    9605
NP_955452                                                              15    9605
XP_006722857                                                           15    9605
XP_006722856                                                           15    9605
XP_005260040                                                           15    9605
XP_005256671                                                           15    9605
XP_005248400                                                           15    9605
XP_005248401                                                           15    9605
XP_006713543                                                           15    9605
>NP_000213
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>NP_001087241
          Length = 972

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>XP_006714101
          Length = 526

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>XP_005265799
          Length = 973

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>XP_005265798
          Length = 976

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>XP_005265797
          Length = 977

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VPVVSVSK
Sbjct: 211 VPVVSVSK 218
>NP_001058
          Length = 1531

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VVPVVSVSK 9
           + P+V VSK
Sbjct: 574 ITPIVKVSK 582
>NP_001013725
          Length = 1649

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVP+VSV
Sbjct: 1530 VVPIVSV 1536
>NP_001229416
          Length = 1837

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1481 VVPVISV 1487
>NP_001229417
          Length = 1892

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1481 VVPVISV 1487
>NP_055852
          Length = 1842

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1486 VVPVISV 1492
>XP_005257689
          Length = 1519

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VVPVVSVSK 9
           + P+V VSK
Sbjct: 562 ITPIVKVSK 570
>XP_005254449
          Length = 1626

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVP+VSV
Sbjct: 1530 VVPIVSV 1536
>XP_005269712
          Length = 1800

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1452 VVPVISV 1458
>XP_006717788
          Length = 1829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1481 VVPVISV 1487
>XP_005269710
          Length = 1834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1486 VVPVISV 1492
>XP_005269709
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1452 VVPVISV 1458
>XP_005269708
          Length = 1897

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1486 VVPVISV 1492
>XP_005269706
          Length = 1900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1481 VVPVISV 1487
>XP_005269705
          Length = 1905

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    VVPVVSV 7
            VVPV+SV
Sbjct: 1486 VVPVISV 1492
>NP_001012660
          Length = 354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VVPVVSV 7
           V+PVVSV
Sbjct: 126 VIPVVSV 132
>NP_001277189
          Length = 736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 209 VVPEVSVS 216
>NP_055968
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 209 VVPEVSVS 216
>NP_001006642
          Length = 503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 480 VIPAVSIS 487
>NP_077008
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 445 VIPAVSIS 452
>NP_001252543
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 478 VIPAVSIS 485
>NP_001006643
          Length = 489

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 466 VIPAVSIS 473
>NP_852111
          Length = 669

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VP+++VSK
Sbjct: 573 VPLITVSK 580
>NP_000136
          Length = 695

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   VPVVSVSK 9
           VP+++VSK
Sbjct: 599 VPLITVSK 606
>NP_443133
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 446 VIPAVSIS 453
>NP_001277188
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 121 VVPEVSVS 128
>NP_055400
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VPVVSVS 8
           VP++SVS
Sbjct: 450 VPIISVS 456
>NP_060733
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           +VPVVS S+
Sbjct: 422 IVPVVSQSE 430
>XP_006722947
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 389 VIPAVSIS 396
>XP_005251746
          Length = 366

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 343 VIPAVSIS 350
>XP_006717012
          Length = 378

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 355 VIPAVSIS 362
>XP_006717011
          Length = 481

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 458 VIPAVSIS 465
>XP_005251745
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           V+P VS+S
Sbjct: 492 VIPAVSIS 499
>XP_005248759
          Length = 1951

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 121 VVPEVSVS 128
>XP_006715489
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 209 VVPEVSVS 216
>XP_005248758
          Length = 2039

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP VSVS
Sbjct: 209 VVPEVSVS 216
>XP_005246562
          Length = 531

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VPVVSVS 8
           VP++SVS
Sbjct: 410 VPIISVS 416
>XP_005246561
          Length = 615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VPVVSVS 8
           VP++SVS
Sbjct: 494 VPIISVS 500
>XP_006712103
          Length = 1175

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           +VPVVS S+
Sbjct: 162 IVPVVSQSE 170
>XP_006712102
          Length = 1313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           +VPVVS S+
Sbjct: 300 IVPVVSQSE 308
>NP_000142
          Length = 357

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VVPVVSVS 8
           VVP+ SVS
Sbjct: 332 VVPLASVS 339
>NP_001138508
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVVSVSK 9
           PVVS+S+
Sbjct: 504 PVVSISR 510
>NP_001157912
          Length = 494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VVPVVSVSK 9
           VVP V VSK
Sbjct: 422 VVPRVRVSK 430
>NP_031383
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   PVVSVSK 9
           PVVS+S+
Sbjct: 504 PVVSISR 510
>NP_004924
          Length = 814

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VVPVVSVSK 9
          V+P +SVS+
Sbjct: 48 VIPPISVSE 56
>NP_001136026
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           VVP++S+S
Sbjct: 310 VVPLLSIS 317
>NP_848613
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           ++PVVSV+
Sbjct: 318 LIPVVSVA 325
>NP_001129507
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           VVP++S+S
Sbjct: 310 VVPLLSIS 317
>NP_689967
          Length = 777

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           V+ VVS+SK
Sbjct: 476 VLKVVSISK 484
>NP_060192
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           VVP++S+S
Sbjct: 310 VVPLLSIS 317
>NP_955452
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           ++P VSV+K
Sbjct: 143 ILPFVSVAK 151
>XP_006722857
          Length = 398

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  VVPVVSVS 8
          VVP++S+S
Sbjct: 49 VVPLLSIS 56
>XP_006722856
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           VVP++S+S
Sbjct: 96  VVPLLSIS 103
>XP_005260040
          Length = 630

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           VVP++S+S
Sbjct: 310 VVPLLSIS 317
>XP_005256671
          Length = 508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   VVPVVSVS 8
           ++PVVSV+
Sbjct: 318 LIPVVSVA 325
>XP_005248400
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VVPVVSVSK 9
           VVP V VSK
Sbjct: 228 VVPRVRVSK 236
>XP_005248401
          Length = 300

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   VVPVVSVSK 9
           VVP V VSK
Sbjct: 228 VVPRVRVSK 236
>XP_006713543
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVPVVSVSK 9
           ++P VSV+K
Sbjct: 143 ILPFVSVAK 151
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.126    0.309 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 523,581
Number of extensions: 738
Number of successful extensions: 63
Number of sequences better than 10000.0: 63
Number of HSP's gapped: 63
Number of HSP's successfully gapped: 63
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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