Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              20     390
NP_066124                                                              20     390
XP_006717999                                                           20     390
NP_003256                                                              17    4312
NP_065756                                                              17    4312
NP_001186036                                                           17    4312
NP_001123508                                                           17    4312
NP_001123507                                                           17    4312
NP_001123506                                                           17    4312
NP_001123505                                                           17    4312
NP_067023                                                              17    4312
XP_005255506                                                           17    4312
XP_006720970                                                           17    4312
XP_006718704                                                           17    4312
XP_006714357                                                           17    4312
NP_001158238                                                           16    7355
NP_207646                                                              16    7355
NP_001193900                                                           16    7355
NP_002828                                                              16    7355
NP_001103224                                                           16    7355
NP_001193901                                                           16    7355
NP_078997                                                              16    7355
NP_008816                                                              16    7355
XP_005256014                                                           16    7355
XP_006720523                                                           16    7355
XP_006720345                                                           16    7355
XP_005268192                                                           16    7355
XP_005268191                                                           16    7355
XP_006719593                                                           16    7355
XP_006719592                                                           16    7355
XP_006719591                                                           16    7355
XP_005273127                                                           16    7355
NP_001139669                                                           16    7355
NP_775779                                                              16    7355
NP_005735                                                              16    7355
NP_001273283                                                           15    9605
NP_683766                                                              15    9605
NP_001273284                                                           15    9605
NP_057263                                                              15    9605
NP_036417                                                              15    9605
NP_001129430                                                           15    9605
NP_001129428                                                           15    9605
NP_001129427                                                           15    9605
NP_001094385                                                           15    9605
NP_003297                                                              15    9605
NP_001182209                                                           15    9605
XP_005255865                                                           15    9605
XP_006721206                                                           15    9605
NP_001129429                                                           15    9605
>NP_065681
          Length = 1072

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLHFNV 9
           VLLLHFNV
Sbjct: 388 VLLLHFNV 395
>NP_066124
          Length = 1114

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLHFNV 9
           VLLLHFNV
Sbjct: 388 VLLLHFNV 395
>XP_006717999
          Length = 1207

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VLLLHFNV 9
           VLLLHFNV
Sbjct: 481 VLLLHFNV 488
>NP_003256
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VVLLLHF 7
           +VLL+HF
Sbjct: 719 IVLLIHF 725
>NP_065756
          Length = 553

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVLLLHFNV 9
           V LLLH+++
Sbjct: 138 VALLLHYSI 146
>NP_001186036
          Length = 559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVLLLHFNV 9
           V LLLH+++
Sbjct: 138 VALLLHYSI 146
>NP_001123508
          Length = 189

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 47 VLIHFNV 53
>NP_001123507
          Length = 189

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 47 VLIHFNV 53
>NP_001123506
          Length = 224

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 47 VLIHFNV 53
>NP_001123505
          Length = 208

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 66 VLIHFNV 72
>NP_067023
          Length = 243

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 66 VLIHFNV 72
>XP_005255506
          Length = 559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVLLLHFNV 9
           V LLLH+++
Sbjct: 138 VALLLHYSI 146
>XP_006720970
          Length = 559

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VVLLLHFNV 9
           V LLLH+++
Sbjct: 138 VALLLHYSI 146
>XP_006718704
          Length = 174

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3  LLLHFNV 9
          +L+HFNV
Sbjct: 47 VLIHFNV 53
>XP_006714357
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VVLLLHF 7
           +VLL+HF
Sbjct: 719 IVLLIHF 725
>NP_001158238
          Length = 2789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VLLLHFN 8
           +LL+H+N
Sbjct: 645 ILLVHYN 651
>NP_207646
          Length = 2572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    VLLLHFN 8
            +LL+H+N
Sbjct: 1205 ILLVHYN 1211
>NP_001193900
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 497 VLLIHENV 504
>NP_002828
          Length = 1997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 587 VLLIHENV 594
>NP_001103224
          Length = 2215

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 805 VLLIHENV 812
>NP_001193901
          Length = 1907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 587 VLLIHENV 594
>NP_078997
          Length = 3616

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    VLLLHFN 8
            +LL+H+N
Sbjct: 1555 ILLVHYN 1561
>NP_008816
          Length = 3703

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    VLLLHFN 8
            +LL+H+N
Sbjct: 1559 ILLVHYN 1565
>XP_005256014
          Length = 3702

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    VLLLHFN 8
            +LL+H+N
Sbjct: 1558 ILLVHYN 1564
>XP_006720523
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VLLLHFN 8
           +LL HFN
Sbjct: 133 ILLSHFN 139
>XP_006720345
          Length = 1522

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VLLLHFN 8
           +LL+H+N
Sbjct: 155 ILLVHYN 161
>XP_005268192
          Length = 1602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2   VLLLHFN 8
           +LL+H+N
Sbjct: 235 ILLVHYN 241
>XP_005268191
          Length = 2572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    VLLLHFN 8
            +LL+H+N
Sbjct: 1205 ILLVHYN 1211
>XP_006719593
          Length = 1304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 805 VLLIHENV 812
>XP_006719592
          Length = 2012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 587 VLLIHENV 594
>XP_006719591
          Length = 2230

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLL+H NV
Sbjct: 805 VLLIHENV 812
>XP_005273127
          Length = 421

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLLL FN+
Sbjct: 310 VLLLTFNI 317
>NP_001139669
          Length = 7081

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LLLHFNV 9
            LL+HF+V
Sbjct: 6549 LLMHFSV 6555
>NP_775779
          Length = 490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VLLLHFNV 9
           VLLL FN+
Sbjct: 379 VLLLTFNI 386
>NP_005735
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VLLLHFN 8
           +LL HFN
Sbjct: 133 ILLSHFN 139
>NP_001273283
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VVLLLHF 7
           V+LL HF
Sbjct: 460 VILLCHF 466
>NP_683766
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VVLLLHF 7
           V+LL HF
Sbjct: 635 VILLCHF 641
>NP_001273284
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   VVLLLHF 7
           V+LL HF
Sbjct: 564 VILLCHF 570
>NP_057263
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
>NP_036417
          Length = 1017

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LLLHFNV 9
           LLLH++V
Sbjct: 218 LLLHYSV 224
>NP_001129430
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
>NP_001129428
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
>NP_001129427
          Length = 893

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
>NP_001094385
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  LLHFNV 9
          L HFNV
Sbjct: 14 LFHFNV 19
>NP_003297
          Length = 982

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
>NP_001182209
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   VLLLHFN 8
           +LLLH N
Sbjct: 115 ILLLHHN 121
>XP_005255865
          Length = 917

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  LLHFNV 9
          L HFNV
Sbjct: 14 LFHFNV 19
>XP_006721206
          Length = 921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 5/6 (83%)

Query: 4  LLHFNV 9
          L HFNV
Sbjct: 9  LFHFNV 14
>NP_001129429
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VVLLLHFNV 9
          + LLL FNV
Sbjct: 86 IELLLSFNV 94
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.160    0.473 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,024
Number of extensions: 739
Number of successful extensions: 49
Number of sequences better than 10000.0: 49
Number of HSP's gapped: 49
Number of HSP's successfully gapped: 49
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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