Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006086                                                              17    3301
NP_001098999                                                           17    3301
XP_006714052                                                           17    3301
XP_005248100                                                           17    3301
NP_057613                                                              16    7355
NP_620168                                                              16    7355
NP_055021                                                              16    7355
NP_001171473                                                           16    7355
XP_006722719                                                           16    7355
XP_006722718                                                           16    7355
XP_006722717                                                           16    7355
XP_006719897                                                           16    7355
XP_006719896                                                           16    7355
XP_006719895                                                           16    7355
XP_005266476                                                           16    7355
>NP_006086
          Length = 1164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTVITLAVG 9
           V V+TLA+G
Sbjct: 792 VKVVTLAIG 800
>NP_001098999
          Length = 1149

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTVITLAVG 9
           V V+TLA+G
Sbjct: 777 VKVVTLAIG 785
>XP_006714052
          Length = 1000

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTVITLAVG 9
           V V+TLA+G
Sbjct: 628 VKVVTLAIG 636
>XP_005248100
          Length = 1164

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTVITLAVG 9
           V V+TLA+G
Sbjct: 792 VKVVTLAIG 800
>NP_057613
          Length = 1188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTVITLAVG 9
           V  ITLA+G
Sbjct: 812 VKAITLAIG 820
>NP_620168
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VITLAVG 9
           V+TLA+G
Sbjct: 932 VVTLAIG 938
>NP_055021
          Length = 79

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  VTVITLAVG 9
          +TV+ LA+G
Sbjct: 21 LTVVLLAIG 29
>NP_001171473
          Length = 1263

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VITLAVG 9
           V+TLA+G
Sbjct: 895 VVTLAIG 901
>XP_006722719
          Length = 1224

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VITLAVG 9
           V+TLA+G
Sbjct: 856 VVTLAIG 862
>XP_006722718
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VITLAVG 9
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006722717
          Length = 1310

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VITLAVG 9
           V+TLA+G
Sbjct: 942 VVTLAIG 948
>XP_006719897
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTVITLAVG 9
           V  ITLA+G
Sbjct: 772 VKAITLAIG 780
>XP_006719896
          Length = 1005

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTVITLAVG 9
           V  ITLA+G
Sbjct: 629 VKAITLAIG 637
>XP_006719895
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTVITLAVG 9
           V  ITLA+G
Sbjct: 706 VKAITLAIG 714
>XP_005266476
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTVITLAVG 9
           V  ITLA+G
Sbjct: 772 VKAITLAIG 780
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.140    0.353 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 295,142
Number of extensions: 450
Number of successful extensions: 15
Number of sequences better than 10000.0: 15
Number of HSP's gapped: 15
Number of HSP's successfully gapped: 15
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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