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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_127493                                                              15    9605
NP_127494                                                              15    9605
NP_001157108                                                           15    9605
NP_001509                                                              15    9605
NP_127492                                                              15    9605
NP_066554                                                              15    9605
NP_061875                                                              15    9605
NP_001265536                                                           15    9605
NP_055239                                                              15    9605
NP_001265537                                                           15    9605
NP_001265535                                                           15    9605
NP_853514                                                              15    9605
NP_001186                                                              15    9605
XP_005261676                                                           15    9605
XP_006724320                                                           15    9605
XP_006719760                                                           15    9605
XP_006719759                                                           15    9605
XP_006719758                                                           15    9605
XP_005254048                                                           15    9605
XP_006719757                                                           15    9605
XP_005250353                                                           15    9605
XP_006716008                                                           15    9605
XP_006716007                                                           15    9605
XP_006716006                                                           15    9605
XP_006716005                                                           15    9605
XP_006716004                                                           15    9605
XP_006716003                                                           15    9605
XP_006716002                                                           15    9605
XP_005250348                                                           15    9605
XP_005264435                                                           15    9605
XP_005264434                                                           15    9605
XP_005264433                                                           15    9605
XP_005264432                                                           15    9605
XP_005264431                                                           15    9605
NP_001155177                                                           15    9605
NP_997194                                                              15    9605

>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VTSAVREPK 9
           +TSAVREPK
Sbjct: 208 MTSAVREPK 216



>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   VTSAVREPK 9
           +TSAVREPK
Sbjct: 208 MTSAVREPK 216



>NP_127493
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 678 TSAVRTP 684



>NP_127494
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 677 TSAVRTP 683



>NP_001157108
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 676 TSAVRTP 682



>NP_001509
          Length = 957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 657 TSAVRTP 663



>NP_127492
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 698 TSAVRTP 704



>NP_066554
          Length = 1020

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VTSAVRE 7
           VTSA+RE
Sbjct: 267 VTSALRE 273



>NP_061875
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 357 VTSCTKEPE 365



>NP_001265536
          Length = 554

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS +RE K
Sbjct: 92  VTSGMREEK 100



>NP_055239
          Length = 170

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VTSAVRE 7
           VTSA+RE
Sbjct: 137 VTSALRE 143



>NP_001265537
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VTSAVREPK 9
          VTS +RE K
Sbjct: 64 VTSGMREEK 72



>NP_001265535
          Length = 526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VTSAVREPK 9
          VTS +RE K
Sbjct: 64 VTSGMREEK 72



>NP_853514
          Length = 1732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   VTSAVREP 8
           VTSA  EP
Sbjct: 217 VTSAASEP 224



>NP_001186
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS +RE K
Sbjct: 203 VTSGMREEK 211



>XP_005261676
          Length = 986

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VTSAVRE 7
           VTSA+RE
Sbjct: 267 VTSALRE 273



>XP_006724320
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VTSAVRE 7
           VTSA+RE
Sbjct: 267 VTSALRE 273



>XP_006719760
          Length = 504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 387 VTSEDKEPK 395



>XP_006719759
          Length = 577

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 460 VTSEDKEPK 468



>XP_006719758
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 508 VTSEDKEPK 516



>XP_005254048
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 504 VTSEDKEPK 512



>XP_006719757
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 508 VTSEDKEPK 516



>XP_005250353
          Length = 969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 669 TSAVRTP 675



>XP_006716008
          Length = 988

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 688 TSAVRTP 694



>XP_006716007
          Length = 989

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 689 TSAVRTP 695



>XP_006716006
          Length = 990

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 690 TSAVRTP 696



>XP_006716005
          Length = 998

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 698 TSAVRTP 704



>XP_006716004
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 703 TSAVRTP 709



>XP_006716003
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 709 TSAVRTP 715



>XP_006716002
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 710 TSAVRTP 716



>XP_005250348
          Length = 1010

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TSAVREP 8
           TSAVR P
Sbjct: 710 TSAVRTP 716



>XP_005264435
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 359 VTSCTKEPE 367



>XP_005264434
          Length = 843

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 274 VTSCTKEPE 282



>XP_005264433
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 359 VTSCTKEPE 367



>XP_005264432
          Length = 899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 359 VTSCTKEPE 367



>XP_005264431
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EP+
Sbjct: 359 VTSCTKEPE 367



>NP_001155177
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  VTSAVREPK 9
          VTS +RE K
Sbjct: 78 VTSGMREEK 86



>NP_997194
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTSAVREPK 9
           VTS  +EPK
Sbjct: 456 VTSEDKEPK 464



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.116    0.294 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 544,045
Number of extensions: 512
Number of successful extensions: 38
Number of sequences better than 10000.0: 38
Number of HSP's gapped: 38
Number of HSP's successfully gapped: 38
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)