Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004351                                                              18    1935
XP_005251865                                                           18    1935
XP_005251864                                                           18    1935
NP_055745                                                              18    1935
NP_001155048                                                           17    2528
NP_056404                                                              17    2528
NP_443171                                                              17    4312
NP_001191195                                                           17    4312
NP_001191196                                                           17    4312
NP_000800                                                              17    4312
NP_001123465                                                           17    4312
XP_006714066                                                           17    4312
XP_005264664                                                           17    4312
XP_005264663                                                           17    4312
XP_005264662                                                           17    4312
XP_006711210                                                           17    4312
XP_006711209                                                           17    4312
XP_005244929                                                           17    4312
XP_006711208                                                           17    4312
NP_115895                                                              17    4312
NP_001258625                                                           16    5631
NP_001258627                                                           16    5631
NP_004290                                                              16    5631
NP_001258628                                                           16    5631
NP_000799                                                              16    5631
NP_777596                                                              16    5631
NP_001258626                                                           16    5631
XP_005274716                                                           16    5631
NP_112092                                                              16    7355
NP_031377                                                              16    7355
NP_663612                                                              16    7355
NP_005631                                                              16    7355
XP_006724281                                                           16    7355
XP_006724280                                                           16    7355
XP_005258397                                                           16    7355
XP_005258396                                                           16    7355
XP_006722591                                                           16    7355
XP_005262913                                                           16    7355
NP_000213                                                              15    9605
NP_001087241                                                           15    9605
NP_001273659                                                           15    9605
NP_201567                                                              15    9605
NP_536856                                                              15    9605
NP_612191                                                              15    9605
NP_612190                                                              15    9605
NP_113648                                                              15    9605
NP_066984                                                              15    9605
NP_001128583                                                           15    9605
XP_005251914                                                           15    9605
XP_006717092                                                           15    9605
XP_006717091                                                           15    9605
XP_005251912                                                           15    9605
XP_006717090                                                           15    9605
XP_006715302                                                           15    9605
XP_005265799                                                           15    9605
XP_005265798                                                           15    9605
XP_005265797                                                           15    9605
>NP_004351
          Length = 882

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   VTLNTVG 7
           VTLNTVG
Sbjct: 114 VTLNTVG 120
>XP_005251865
          Length = 682

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  VTLNTVG 7
          VTLNTVG
Sbjct: 12 VTLNTVG 18
>XP_005251864
          Length = 683

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  VTLNTVG 7
          VTLNTVG
Sbjct: 12 VTLNTVG 18
>NP_055745
          Length = 683

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1  VTLNTVG 7
          VTLNTVG
Sbjct: 12 VTLNTVG 18
>NP_001155048
          Length = 630

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TLNTVGTT 9
           T+NT+GT+
Sbjct: 228 TINTIGTS 235
>NP_056404
          Length = 718

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   TLNTVGTT 9
           T+NT+GT+
Sbjct: 228 TINTIGTS 235
>NP_443171
          Length = 734

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           VTLN  GT+
Sbjct: 558 VTLNVTGTS 566
>NP_001191195
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           T+NT+G T
Sbjct: 470 TVNTIGAT 477
>NP_001191196
          Length = 484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           T+NT+G T
Sbjct: 419 TVNTIGAT 426
>NP_000800
          Length = 554

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           T+NT+G T
Sbjct: 489 TVNTIGAT 496
>NP_001123465
          Length = 718

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLNTVGT 8
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>XP_006714066
          Length = 544

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           T+NT+G T
Sbjct: 479 TVNTIGAT 486
>XP_005264664
          Length = 572

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLNTVGT 8
           +LNTVGT
Sbjct: 283 SLNTVGT 289
>XP_005264663
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLNTVGT 8
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>XP_005264662
          Length = 710

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLNTVGT 8
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>XP_006711210
          Length = 485

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           VTLN  GT+
Sbjct: 309 VTLNVTGTS 317
>XP_006711209
          Length = 613

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           VTLN  GT+
Sbjct: 558 VTLNVTGTS 566
>XP_005244929
          Length = 647

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           VTLN  GT+
Sbjct: 471 VTLNVTGTS 479
>XP_006711208
          Length = 734

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           VTLN  GT+
Sbjct: 558 VTLNVTGTS 566
>NP_115895
          Length = 707

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TLNTVGT 8
           +LNTVGT
Sbjct: 429 SLNTVGT 435
>NP_001258625
          Length = 752

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 296 VTLGTLGT 303
>NP_001258627
          Length = 726

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 270 VTLGTLGT 277
>NP_004290
          Length = 753

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 297 VTLGTLGT 304
>NP_001258628
          Length = 713

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 257 VTLGTLGT 264
>NP_000799
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TLNTVGTT 9
           T N VGTT
Sbjct: 395 TFNIVGTT 402
>NP_777596
          Length = 692

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 346 VTLGTLGT 353
>NP_001258626
          Length = 712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   VTLNTVGT 8
           VTL T+GT
Sbjct: 256 VTLGTLGT 263
>XP_005274716
          Length = 491

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   TLNTVGTT 9
           T N VGTT
Sbjct: 394 TFNIVGTT 401
>NP_112092
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           V  N+VGTT
Sbjct: 118 VVSNSVGTT 126
>NP_031377
          Length = 1228

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           +LNTVG T
Sbjct: 155 SLNTVGGT 162
>NP_663612
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           V  N+VGTT
Sbjct: 118 VVSNSVGTT 126
>NP_005631
          Length = 862

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           VTL++VG T
Sbjct: 410 VTLHSVGPT 418
>XP_006724281
          Length = 337

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           V  N+VGTT
Sbjct: 118 VVSNSVGTT 126
>XP_006724280
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   VTLNTVGTT 9
           V  N+VGTT
Sbjct: 196 VVSNSVGTT 204
>XP_005258397
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           VTL++VG T
Sbjct: 410 VTLHSVGPT 418
>XP_005258396
          Length = 625

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           VTL++VG T
Sbjct: 410 VTLHSVGPT 418
>XP_006722591
          Length = 827

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           VTL++VG T
Sbjct: 410 VTLHSVGPT 418
>XP_005262913
          Length = 1193

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   TLNTVGTT 9
           +LNTVG T
Sbjct: 155 SLNTVGGT 162
>NP_000213
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           V +N+VG+T
Sbjct: 955 VRINSVGST 963
>NP_001087241
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           V +N+VG+T
Sbjct: 951 VRINSVGST 959
>NP_001273659
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 531 TINTVG 536
>NP_201567
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VTLNTVG 7
           VTL TVG
Sbjct: 208 VTLTTVG 214
>NP_536856
          Length = 657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 531 TINTVG 536
>NP_612191
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VTLNTVG 7
           VTL TVG
Sbjct: 277 VTLTTVG 283
>NP_612190
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VTLNTVG 7
           VTL TVG
Sbjct: 277 VTLTTVG 283
>NP_113648
          Length = 332

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VTLNTVG 7
           +TL+TVG
Sbjct: 217 ITLSTVG 223
>NP_066984
          Length = 538

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   VTLNTVG 7
           VTL TVG
Sbjct: 272 VTLTTVG 278
>NP_001128583
          Length = 271

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VTLNTVG 7
           +TL+TVG
Sbjct: 217 ITLSTVG 223
>XP_005251914
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 498 TINTVG 503
>XP_006717092
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 549 TINTVG 554
>XP_006717091
          Length = 675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 549 TINTVG 554
>XP_005251912
          Length = 719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 531 TINTVG 536
>XP_006717090
          Length = 737

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   TLNTVG 7
           T+NTVG
Sbjct: 549 TINTVG 554
>XP_006715302
          Length = 265

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   VTLNTVG 7
           +TL+TVG
Sbjct: 217 ITLSTVG 223
>XP_005265799
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           V +N+VG+T
Sbjct: 952 VRINSVGST 960
>XP_005265798
          Length = 976

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           V +N+VG+T
Sbjct: 955 VRINSVGST 963
>XP_005265797
          Length = 977

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   VTLNTVGTT 9
           V +N+VG+T
Sbjct: 956 VRINSVGST 964
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.306    0.120    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 384,361
Number of extensions: 746
Number of successful extensions: 57
Number of sequences better than 10000.0: 57
Number of HSP's gapped: 57
Number of HSP's successfully gapped: 57
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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