Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_065962                                                              17    3301
NP_002510                                                              17    3301
XP_005250743                                                           17    3301
XP_006716234                                                           17    3301
NP_055753                                                              16    7355
NP_055572                                                              16    7355
XP_006719357                                                           16    7355
XP_006719356                                                           16    7355
XP_006719355                                                           16    7355
XP_006719354                                                           16    7355
XP_006719353                                                           16    7355
NP_001009899                                                           15    9605
NP_060034                                                              15    9605
XP_006719539                                                           15    9605
XP_005247266                                                           15    9605
XP_005247265                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2575 VSVSESNVL 2583
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2596 VSVSESNVL 2604
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2606 VSVSESNVL 2614
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2606 VSVSESNVL 2614
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2575 VSVSESNVL 2583
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2585 VSVSESNVL 2593
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2606 VSVSESNVL 2614
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2593 VSVSESNVL 2601
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2596 VSVSESNVL 2604
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    VSVSQSNVL 9
            VSVS+SNVL
Sbjct: 2606 VSVSESNVL 2614
>NP_065962
          Length = 1894

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSVSQSNVL 9
           +SVSQ NVL
Sbjct: 568 ISVSQYNVL 576
>NP_002510
          Length = 1427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           SVSQSNV+
Sbjct: 881 SVSQSNVV 888
>XP_005250743
          Length = 1894

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSVSQSNVL 9
           +SVSQ NVL
Sbjct: 568 ISVSQYNVL 576
>XP_006716234
          Length = 1894

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   VSVSQSNVL 9
           +SVSQ NVL
Sbjct: 568 ISVSQYNVL 576
>NP_055753
          Length = 919

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 603 TVSQSNVV 610
>NP_055572
          Length = 1016

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           S+SQSN++
Sbjct: 234 SISQSNLM 241
>XP_006719357
          Length = 567

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 210 TVSQSNVV 217
>XP_006719356
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 603 TVSQSNVV 610
>XP_006719355
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 603 TVSQSNVV 610
>XP_006719354
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 603 TVSQSNVV 610
>XP_006719353
          Length = 960

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SVSQSNVL 9
           +VSQSNV+
Sbjct: 603 TVSQSNVV 610
>NP_001009899
          Length = 2245

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSVSQSN 7
           VSVSQ+N
Sbjct: 851 VSVSQAN 857
>NP_060034
          Length = 2551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VSVSQSNV 8
            +SVSQS V
Sbjct: 1690 ISVSQSTV 1697
>XP_006719539
          Length = 2246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    VSVSQSNV 8
            +SVSQS V
Sbjct: 1690 ISVSQSTV 1697
>XP_005247266
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSVSQSN 7
           VSVSQ+N
Sbjct: 795 VSVSQAN 801
>XP_005247265
          Length = 2211

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   VSVSQSN 7
           VSVSQ+N
Sbjct: 817 VSVSQAN 823
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.110    0.235 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 272,865
Number of extensions: 319
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)

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